目的：考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体，并制备速释型固体分散体。
Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.
方法：以聚乙烯吡咯烷酮（PVP）、聚乙二醇-6000（PEG-6000）为载体，溶剂法和溶剂熔融法制备固体分散体，并进行体外溶出度研究。
Method: carvedilol solid dispersions were prepared by solvent-melting and coevaporation methods with PEG-6000 and PVP as carriers, the study on the dissolution was conducted in vitro.
载体为PVP所制固体分散体的体外溶出行为总体优于载体为PEG- 6000的固体分散体。
The in vitro dissolubility of solid dispersions with PVP as carrier was faster than that of solid dispersions with PEG-6000 as carrier.
方法以不同分子量不同比例的聚乙二醇为载体，以熔融法制备固体分散体，并进行体外溶出度研究和DSC扫描。
METHODS Preparing the solid dispersion by melting method at different drug-to-PEG ratios with different PEG moleculars and studying the preparation with dissolution rate in vitro and DSC method.
方法以聚乙二醇6000为载体，溶剂-熔融法制备sud - 35固体分散体。
METHODS Solid dispersions of SUD-35 were prepared by solvent-fusion method with PEG6000 as carrier.
方法选用聚乙二醇为载体，采用溶剂-熔融法制备依托度酸固体分散体，通过差热分析对固体分散体进行鉴定。
Methods Etodolac solid dispersion was prepared with PEG as carrier by solvent-fusion method and identified by differential thermal analysis.
方法选用聚乙二醇为载体，采用溶剂-熔融法制备依托度酸固体分散体，通过差热分析对固体分散体进行鉴定。
Methods Etodolac solid dispersion was prepared with PEG as carrier by solvent-fusion method and identified by differential thermal analysis.
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