本发明涉及包含抗体替代轻链序列的构建体和文库。
The invention concerns constructs and libraries comprising antibody surrogate light chain sequences.
核苷酸序列分析表明所克隆基因分别为抗体轻、重链可变区基因。
The nucleotide sequence analyses indicated that the cloned genes coded the variable light and heavy chain domains from mouse antibodies respectively.
推导的氨基酸序列具有典型的抗体轻、重链可变区特征。
Two amino acid sequences deduced had typical features of Ig heavy and light chains' variable regions.
结果:克隆的基因序列符合小鼠轻、重链可变区基因的特征;
RESULTS: The VH and VL genes were homologous with the published gene sequences of mouse antibody variable region.
结果:克隆的基因序列符合小鼠轻、重链可变区基因的特征;
RESULTS: The VH and VL genes were homologous with the published gene sequences of mouse antibody variable region.
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