目的：探讨凋亡在软骨细胞分化中的作用。
Objective to explore the effect of apoptosis on chondrocyte differentiation.
随着增殖层细胞逐渐向肥大层软骨细胞分化，软骨厚度逐渐增加。
With the development of articular, the proliferation cells differentiated into hypertrophic cells, and the cartilage thickened.
目的：探讨人脐带血间充质干细胞存在及体外向成软骨细胞分化的可能性。
Objective To explore whether mesenchymal stem cells could be isolated from human umbilical cord blood and would be able to differentiate into chondroblast in vitro.
利用血液去培育干细胞获得成功以后，朱敏设法诱导它们分化成三种细胞系：先是骨骼和软骨细胞，然后是肌细胞，再是神经元。
Using blood to nourish and grow the stem cells, Zhu managed to induce them to differentiate into three lineages: first bone and cartilage, then muscle, and then neuron.
结论：从未退变的椎间盘分离的纤维环细胞能在体外分化为脂肪细胞、格根包尔氏细胞、软骨细胞、神经元及内皮细胞。
Conclusions Anulus fibrosus cells isolated from nondegenerative intervertebral discs can differentiate into adipocytes, osteoblasts, chondrocytes, neurons, and endothelial cells in vitro.
目的：研究关节软骨细胞的原代分离及体外培养，了解表皮细胞生长因子(EGF)对其生长和去分化趋势的影响。
Objective: To study the isolation and culture of chondrocyte of joint cartilage, and the influence of EGF on its growth and dedifferentiation.
骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质，因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨，在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
BMP分子可以诱导间充质细胞分化为软骨细胞，促进合成细胞外基质，抑制软骨细胞的终末分化。
BMP may induce mesenchymal cells to differentiate into chondrocytes, promote the synthesis of extracellular matrix and inhibit the terminal differentiation of chondrocytes.
目的从成体人牙周组织中分离培养牙周韧带干细胞，研究其分化为软骨细胞的可行性。
Objective to isolate and cultivate human periodontal ligament stem cells (PDLSC) and to investigate the feasibility of PDLSC in vitro differentiation into chondrogenic phenotype.
近年研究表明，胚胎干细胞在细胞因子、激素、微环境等作用下能够分化为软骨细胞。
Recent study shows that, embryonic stem cells can differentiate into cartilage cells in the effect of cytokines, hormones, micro? Environment etc.
本文对近年来胚胎干细胞向软骨细胞定向分化中的各种因素进行综述。
In the is review, the author explore several studies and review the effects of different factors to the differentiation of embryonic stem cell to chondrocyte.
在单层培养的软骨细胞扩展中，FGF-2显示出可以保持分化的潜力，但此种作用在髓核细胞中尚不明确。
FGF-2 has been shown to retain the differentiation potential of monolayer expanded chondrocytic cells. However, its effect on nucleus pulposus cells is not known.
而在成熟骨化的骨基质和分化末期的肥大软骨细胞中，染色呈阴性。
Negative reaction was found in the mature and ossified bone matrix and hypertrophic chondrocytes which were in the late stage of differentiation.
就骨髓基质干细胞分离、诱导分化为软骨细胞的方法、载体材料及目前存在的问题加以综述。
In this article, isolation and differentiate regular of BMSCs, method of BMSCs induced to chondrocytes, scaffold of cartilage tissue engineering and problems of current existent were reviewed.
研究表明，骨髓基质干细胞作为一种具有多向分化潜能的干细胞，在适当的条件下可以被诱导分化成为软骨细胞和成骨细胞。
Studies have shown that bone marrow stromal cells, a kind of pluripotent stem cells, can be induced to differentiate into chondrocytes and osteoblasts under appropriate conditions.
随着骨髓间充质干细胞分化为软骨细胞的深入研究，这些因素的应用必将更为广泛。
With the deep understanding of BMSCs differentiation into cartilage cells, the application of these factors will be more extensive.
目的：观察微重力条件下动态三维诱导骨髓间充质干细胞向软骨细胞的分化，并与静态培养作比较。
AIM: to observe the induction and differentiation of marrow mesenchymal stem cells (MSCs) into chondrocytes under dynamic microgravity and three dimensions (3d), and compare it with static culture.
有研究证实内质网应激能影响软骨细胞的分化，同时也抑制了软骨细胞的合成功能，减少异常蛋白的合成，减轻应激对细胞的损害。
It has been proved that ERS can interfere the differentiation of chondrocyte, decrease the synthesis of abnormal protein, attenuate the injury of cell.
成骨细胞分化，软骨细胞，脂肪细胞。
目的：体外培养兔骨髓间充质干细胞并定向诱导分化为软骨细胞，探讨体外诱导分化为软骨的方法和条件。
OBJECTIVE: to build a method of differentiation of rabbit BMSCs into chondrocytes in vitro and to determine the factors involved in the differentiation process.
选择文章内容与骨髓间充质干细胞分化为软骨细胞有关者，同一领域文献则选择近期发表或发表在权威杂志文章。
The articles addressing BMSCs differentiation into chondrocytes were included. Those in the same field published recently or in authorized journals were included.
骨髓基质干细胞是一种由骨髓中分离获得的具有多种分化潜能的间质干细胞。在体外培养条件下，它可以分化为成骨细胞、软骨细胞、脂肪细胞、甚至于成肌细胞。
Bone marrow stromal stem cells isolated from bone marrow are the special mesenchymal stem cells, which can be differentiated in culture into osteoblasts, chondrocytes, adipocytes, and even myoblasts.
上述去分化型软骨细胞向软骨细胞的再分化用培养基更优选含有T3的方式。
In a preferred embodiment, the above-described medium for the redifferentiation of dedifferentiated chondrocytes into chondrocytes further contains T3.
上述去分化型软骨细胞向软骨细胞的再分化用培养基更优选含有T3的方式。
In a preferred embodiment, the above-described medium for the redifferentiation of dedifferentiated chondrocytes into chondrocytes further contains T3.
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