兼性异染色质是在特定细胞发育命运中可能具有转录活性的异染色质。
Facultative heterochromatin is the heterochromatin that may become transcriptionally active in specific cell development fates.
此外，它还具有“超距作用”和反转录活性。
In addition, it possesses action-at-a-distance and reverse transcriptase activity.
端粒酶是一个特殊的具有反转录活性的核糖核蛋白。
Telomerase a eukaryotic ribonucleoprotein complex contains both essential rna and a protein reverse transcriptase subunit.
相反，组蛋白h1则可抑制各年龄组鼠肝细胞核的转录活性。
Contrast to HMG histone H1 showed obvious inhibition effect on transcriptional activity of all of the rat liver nuclei.
老年大鼠肝染色质功能的改变可能是转录活性改变的主要原因。
These results suggest that the changing of chromatin template activity is the primary cause of change in RNA synthesis with age.
表观遗传调控可以影响基因转录活性而不涉及DNA序列的改变。
An epigenetic event alters the activity of genes without changing their structure.
瞬时转染人胚胎肾细胞293t，用荧光素酶报告基因检测这两种剪切形式的转录活性。
The transcriptional activity of the two splicing variants was detected with a luciferase reporter in transient transfections of human embryonic kidney293T cells.
这些实验的结果是斑点，它们的亮度从基因到基因变化，与所检测基因的转录活性相一致。
The result of these experiments are spots whose brightness varies from gene to gene corresponding to the transcriptional activity of the examined genes.
最近的研究表明，AP-2能通过与其他蛋白的相互作用来调控AP-2下游基因的转录活性。
Recent studies have shown that interaction partners can modulate the transcriptional activity of AP-2 over the downstream targets.
目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动子荧光素酶报告基因载体，并验证其转录活性。
ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.
细胞的分化是一个动态的过程，带动激活和抑制特定的基因组，基因组转录活性和非活性染色质域的划分。
Cellular differentiation is a dynamic process driven by activation and repression of specific sets of genes, partitioning the genome into transcriptionally active and inactive chromatin domains.
Nur77很大程度上是由多种激酶磷酸化，从而可能影响其转录活性以及其亚细胞定位(4,10,11)。
Nur77 is heavily phosphorylated by multiple kinases, which may affect its transactivation activity as well as its subcellular localization (4, 10, 11).
探讨胰腺癌患者围手术期血清免疫抑制酸性蛋白（IAP）和T淋巴细胞rDNA转录活性的变化及其临床意义。
To study the changes in serum immunosuppressive acidic protein (IAP) and T lymphocytes rDNA transcription activity in peripheral blood of patients with pancreatic cancer before and after operation.
在真核细胞，尽管一些转录活性基因和转录沉默基因的调控序列位置常常非常接近，它们的表达却并不互相影响。
In the eukaryotic cells, despite how close the regulation elements of active and inactive genes are frequently, they dot not affect each other expression level.
目的：研究雷洛昔芬对血管内皮细胞雌激素应答元件(ERE)转录活性的影响与雌激素受体(er)亚型的关系。
Objective: to investigate the effect of Raloxifene on the estrogen responsive element (ERE) transcription activity and its relationship with estrogen receptor subtypes in vascular endothelial cells.
在NOS1基因启动子区鉴定了两个正调控区域和两个负调控区域，同时TS A可上调不同长度启动子的转录活性。
Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.
肝脏胰岛素抵抗还表现为脂代谢异常，如甘油三酯释放增加和肝脏脂肪变性，这与FOXO1转录活性增加有密切关系。
Increased triglyceride release and hepatic steatosis are the common features of hepatic insulin resistance, which deeply associated with increased FOXO1 transcription.
自然界中有一类名为转录因子的蛋白可调节(升高或者降低)基因的活性，该技术正是基于该机理。
The technique relies on a natural process by which the activity of genes is raised or lowered by proteins called transcription factors.
Bionor并没有打算研发HIV疫苗，但作为一种方法，称作高活性抗逆转录病毒疗法的艾滋病治疗药物混合物带给了他们突破。
Bionor does not plan to develop the vaccine to protect people from HIV, but as a way to give them a break from the AIDS drug cocktails called highly active antiretroviral therapy or HAART.
病毒癌基因最常为逆转录病毒致癌基因的产物。通常具有转化和蛋白激酶活性。
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
他们发现活性的逆转录酶反转录，直接签署的逆转录病毒复制。
They detected activity of the retroviral enzyme reverse transcriptase, a direct sign of retrovirus replication.
LPL活性调节的这种组织特异性主要是由于不同组织lpl基因转录速率不同所决定的。
The tissue-specific changes in LPL activity can be determined by the different rate of LPL gene transcription in different tissue.
相对荧光素酶活性法检测地塞米松作用后GR转录激活功能的变化。
The transcriptional activation function of GR was evaluated through the detection of relative luciferase activity after dexamethasone treatment.
胰岛素诱导后的脂肪酸合成酶活性升高是在转录水平上调节的。
The change of FAS activity during insulin induction is at the transcriptional level.
作为端粒酶活性的关键决定因子，端粒酶逆转录酶的调控研究已取得了重大进展，但具体机制仍不清楚。
As a critical factor of telomerase activity, much progression has been achieved in the study of regulation of human telomerase reverse transcriptase, but the detail mechanism is still not clear.
以含雌激素反应元件的荧光素酶(ERE -LUC)为报告基因，通过检测荧光素酶活性来确定MDM2是否对ER有转录调节因子的作用。
The effect of MDM2 on the transcriptional activity of er was detected by the reporter gene containing estrogen responsive elements luciferase (ERE-LUC).
逆转录病毒介导的基因转移技术要过渡到临床应用，主要解决如何使病毒载体具有高滴度而不具有复制活性。
In order to use retroviral-mediated gene transfer technology in clinical application, retroviral vector must be of high titer and free of detectable replication-competent retroviruses.
结论慢性间断性低氧能明显增加大鼠肝脏erd (CYP3A2)和ANH (CYP2E1)活性，其机制可能与其在转录水平上提高肝脏cyp3a2和CYP2E1的基因表达水平有关。
Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.
最初大家都只知道它的序列很短，是极其微小的RNA控制片断，大家叫它为反义RNA，它通过置换作用而阻止抑制基因的活性，从而阻碍密码子的转录与翻译活动。
It was previously known that short, tiny control RNA, called antisense RNA, can stop the activity of genes by placing themselves so that "reading" of the code is impeded.
最初大家都只知道它的序列很短，是极其微小的RNA控制片断，大家叫它为反义RNA，它通过置换作用而阻止抑制基因的活性，从而阻碍密码子的转录与翻译活动。
It was previously known that short, tiny control RNA, called antisense RNA, can stop the activity of genes by placing themselves so that "reading" of the code is impeded.
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