这些靶基因在乳腺癌细胞核原发瘤中显示了甲基化相关的转录沉默作用。
These target genes displayed methylation - associated transcriptional silencing in breast cancer cells and primary tumours.
遗传连锁作图、定位克隆、数量特性位点作图、微阵列分析及转录沉默等，是近年来常用的基因组学研究技术。
Genetic linkage mapping, positional cloning, quantitative loci traits mapping, microarrays and transcriptional silencing are genomic technologies that being widely used in recent years.
在真核细胞，尽管一些转录活性基因和转录沉默基因的调控序列位置常常非常接近，它们的表达却并不互相影响。
In the eukaryotic cells, despite how close the regulation elements of active and inactive genes are frequently, they dot not affect each other expression level.
基因组的某些区域天生就以高速率转录成蛋白质，而其它区域则基本上保持沉默。
Some regions of the genome are naturally transcribed into proteins at a high rate, whereas other regions are essentially silent.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
其作用水平主要有三种：位置效应、转录水平的基因沉默和转录后水平的基因沉默。
The positions where transgene silencing occurs mainly are inserting position? transcriptional gene silencing and posttranscriptional gene silencing.
植物中的转录后基因沉默(PTGS)是RNA沉默的一种形式，通过PTGS能对目标RNA进行特异性降解。
Posttranscriptional gene silencing (PTGS) in plants is a form of RNA silencing by which target RNA is degraded in a sequence-specific manner.
本发明还描述了特异结合于本发明的沉默元件的转录阻遏物。
The invention also describes transcriptional repressors which specifically binds onto the silencing element of the invention.
本文通过病毒防御作用、作用模式、沉默信号的传递特点和植物病毒对转录后基因沉默的抑制作用四方面对植物中转录后基因沉默现象进行综述。
In this paper, the affection of PTGS in virus resistance, PTGS mechanism model, transmission of silence message and suppression of virus protein to PTGS are reviewed.
真核生物基因顺式作用元件分为启动子、增强子、沉默子，是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
真核生物基因顺式作用元件分为启动子、增强子、沉默子，是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
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