• 大肠杆菌启动子起始基因转录主要段比较保守序列片断- 10、- 35框它们之间一段长度可变碱基序列组成。

    Escherichia coli promoter, which could initiate transcription of a gene, was mainly consisted of two conserved sequences, -10 box and -35 box, and spacer between them, whose length is changeable.

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  • 转录靶向利用一些肿瘤表达某些特定基因,所以使用基因特异性启动子可以驱动治疗基因达到靶向性治疗目的。

    Transcriptional targeting takes advantage of the fact that some cancer cells express a subset of exclusive genes, and USES these cancer-specific promoters to express the desired transgenes.

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  • 目的预测人类BMP - 2基因启动位置可能转录结合位点

    Objective: to predict the promotor position and transcription factor binding sites of human BMP-2 gene.

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  • 目的克隆并应用计算机分析小鼠lass1基因启动进一步研究细胞衰老过程LAG1基因转录调控奠定基础

    AIM: to clone and analyze the mouse LASS1 gene promoter, so as to lay a foundation for the further research of the transcriptional regulation of LAG1 gene in cell senescence.

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  • 目的研究MTS1基因arf启动子基础转录调控区的转录激活及其与E2 F1转录之间关系。

    Objective to study the effect of E2F1 transcription factor on the transcriptional activity of basic transcriptional regulatory region in the ARF promoter of MTS1 gene.

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  • 目的CTCF一种多功能转录参与启动子调控绝缘功能遗传印记等过程

    Objective: CTCF is a multifunctional transcription factor, which plays many roles in promoter regulation, insulator function and genetic imprinting.

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  • 牛、羊的转录启动具有TATA型看家基因启动子特征

    Their transcription promoter regions have the characteristics of TATA-promoter.

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  • 结果表明基因逆转录病毒载体介导的小鼠骨髓细胞的基因转导中,IRES内部SV40启动子相比,更能保证双基因共同表达

    Results showed that IRES was superior to SV40 promoter for guarantee of genes co expression in bicistronic retrovirus mediated gene therapy.

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  • 目的克隆nkx3.1基因启动检测启动子活性,为研究NKX3.1基因转录调控基本机制奠定基础。

    AIM: To study the basic mechanism of transcriptional regulation, NKX3.1 gene promoter was cloned and its promoter activities in prostate cancer cell lines and other cancer cell lines were tested.

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  • 真核生物基因顺式作用元件分为启动增强沉默调节基因转录特定DNA序列

    Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.

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  • 本发明提供包含CY P启动子核酸序列,该启动子操作性连接编码异源蛋白质的核酸增强核酸的转录

    A nucleic acid sequence including a CYP promoter operably linked to nucleic acid encoding a heterologous protein is provided to increase transcription of the nucleic acid.

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  • 在NOS1基因启动区鉴定了调控区域两个调控区域,同时TS A上调不同长度启动转录活性

    Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.

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  • 目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动荧光素酶报告基因载体验证转录活性

    ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.

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  • 机理研究认为营养除了作用基因启动外,涉及转录调节。

    The nutritional factors not only act on gene promoters but also affect the post_transcriptional processes. This is a major area of nutritional physiology in the…

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  • 机理研究认为营养除了作用基因启动外,涉及转录调节。

    The nutritional factors not only act on gene promoters but also affect the post_transcriptional processes. This is a major area of nutritional physiology in the…

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