大肠杆菌启动子能起始基因的转录,它主要由两段比较保守的序列片断- 10框、- 35框和它们之间一段长度可变的碱基序列组成。
Escherichia coli promoter, which could initiate transcription of a gene, was mainly consisted of two conserved sequences, -10 box and -35 box, and spacer between them, whose length is changeable.
转录靶向性利用一些肿瘤过表达某些特定基因,所以使用此基因特异性启动子可以驱动治疗基因达到靶向性治疗目的。
Transcriptional targeting takes advantage of the fact that some cancer cells express a subset of exclusive genes, and USES these cancer-specific promoters to express the desired transgenes.
目的:预测人类BMP - 2基因启动子位置和可能的转录因子结合位点。
Objective: to predict the promotor position and transcription factor binding sites of human BMP-2 gene.
目的:克隆并应用计算机分析小鼠lass1基因启动子,为进一步研究在细胞衰老过程中LAG1基因的转录调控奠定基础。
AIM: to clone and analyze the mouse LASS1 gene promoter, so as to lay a foundation for the further research of the transcriptional regulation of LAG1 gene in cell senescence.
目的研究MTS1基因arf启动子基础转录调控区的转录激活及其与E2 F1转录因子之间的关系。
Objective to study the effect of E2F1 transcription factor on the transcriptional activity of basic transcriptional regulatory region in the ARF promoter of MTS1 gene.
目的:CTCF是一种多功能的转录因子,参与启动子调控、绝缘子功能和遗传印记等过程。
Objective: CTCF is a multifunctional transcription factor, which plays many roles in promoter regulation, insulator function and genetic imprinting.
牛、羊的转录启动区具有TATA型看家基因启动子特征。
Their transcription promoter regions have the characteristics of TATA-promoter.
结果表明:在双基因逆转录病毒载体介导的小鼠骨髓细胞的基因转导中,IRES与内部SV40启动子相比,更能保证双基因的共同表达。
Results showed that IRES was superior to SV40 promoter for guarantee of genes co expression in bicistronic retrovirus mediated gene therapy.
目的:克隆nkx3.1基因启动子并检测其启动子活性,为研究NKX3.1基因转录调控的基本机制奠定基础。
AIM: To study the basic mechanism of transcriptional regulation, NKX3.1 gene promoter was cloned and its promoter activities in prostate cancer cell lines and other cancer cell lines were tested.
真核生物基因顺式作用元件分为启动子、增强子、沉默子,是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
本发明提供包含CY P启动子的核酸序列,该启动子操作性连接编码异源蛋白质的核酸以增强该核酸的转录。
A nucleic acid sequence including a CYP promoter operably linked to nucleic acid encoding a heterologous protein is provided to increase transcription of the nucleic acid.
在NOS1基因启动子区鉴定了两个正调控区域和两个负调控区域,同时TS A可上调不同长度启动子的转录活性。
Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.
目的构建磷脂酰肌醇蛋白聚糖3 (GPC3)启动子荧光素酶报告基因载体,并验证其转录活性。
ObjectiveTo construct glypican-3 (GPC3) promoter luciferase reporter gene vector, and to analyze its transcriptional activity.
机理研究认为营养因子除了作用于基因启动子外,还涉及转录后的调节。
The nutritional factors not only act on gene promoters but also affect the post_transcriptional processes. This is a major area of nutritional physiology in the…
机理研究认为营养因子除了作用于基因启动子外,还涉及转录后的调节。
The nutritional factors not only act on gene promoters but also affect the post_transcriptional processes. This is a major area of nutritional physiology in the…
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