目的探讨表皮生长因子受体与细胞增殖、转化的关系。
Objective to explore the relationship between epidermal growth factor receptor (EGFR) and cell proliferation and transformation.
结论：骨髓间质干细胞在大鼠心脏内可以转化为血管内皮细胞或分泌血管内皮生长因子，是治疗缺血性心血管疾病理想的细胞来源。
CONCLUSION: MSCs can be transformed into vascular endothelial cells or secrete VEGF in rat hearts, thus is the ideal cell source of therapy in ischemic cardiovascular disease.
目的：研究环氧化酶- 2 (COX - 2)抑制剂对人腹膜间皮细胞(HPMC)转化生长因子- 1 (TGF - 1)表达的影响。
Objective: to investigate the effects of cyclooxygenase-2 (COX-2) inhibitor on TGF-b1 expression in human peritoneal mesothelial cells (HPMC).
目的研究血小板源生长因子(PDGF)对肾小球系膜细胞(MC)表型转化的影响，并探讨丝裂素活化蛋白激酶(MAPK)信号转导途径在其作用中的调控机制。
Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.
最近一项使用表皮生长因子受体抑制剂的临床试验发现，患者的肿瘤细胞表达磷酸化或化学转化水平很高- Akt对这种疗法没有反应“Kwatra博士说。”
A recent clinical trial using an EGFR inhibitor found that patients whose tumors expressed high levels of phosphorylated - or chemically altered - Akt did not respond to treatment, Kwatra said.
最近一项使用表皮生长因子受体抑制剂的临床试验发现，患者的肿瘤细胞表达磷酸化或化学转化水平很高- Akt对这种疗法没有反应“Kwatra博士说。”
A recent clinical trial using an EGFR inhibitor found that patients whose tumors expressed high levels of phosphorylated - or chemically altered - Akt did not respond to treatment, Kwatra said.
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