目的探讨新生小鼠中足细胞损伤对肾小球发育的影响及其机制。
Objective To study the effect of injured podocytes on glomerular maturation and its underlying mechanism in neonatal mice.
目的探讨全反式维甲酸（ATRA）对糖尿病大鼠足细胞损伤的保护作用。
Objective To investigate the protective effect of all-trans retinoic acid (ATRA) on podocyte lesion in diabetic rats.
结论：ORG患者存在足细胞损伤，并表现出足细胞相对密度下降和绝对数目减少两种类型。
Conclusion:A relative decrease of the density and an absolute decrease in the number of podocytes was observed in ORG patients, and varied at different stage of the disease.
结论ATRA可以减少糖尿病大鼠尿足细胞的排泄、降低尿蛋白，对肾脏足细胞损伤具有保护作用。
Conclusions ATRA can decrease the excretion of urinary podocyte and proteinuria. ATRA has a protective effect on podocyte lesion in diabetic rats.
结论ATRA可以减少糖尿病大鼠尿足细胞的排泄、降低尿蛋白，对肾脏足细胞损伤具有保护作用。
Conclusions ATRA can decrease the excretion of urinary podocyte and proteinuria. ATRA has a protective effect on podocyte lesion in diabetic rats.
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