双膦酸盐有趋骨性并有抗骨质疏松症活性。
Bisphosphonate have bone? Seeking affinity, some of them are used as drugs for osteoporosis.
目的设计并合成苯并吡喃酮酯衍生物并探索其趋骨性。
OBJECTIVE to design and synthesize benzopyrone ester derivatives and to test their bone affinity.
结论部分设计的苯并吡喃4酮衍生物具有比四环素更好的趋骨性。
Conclusion Some of the benzopyran-4-one derivatives synthesized have better bone affinities compared with tetracycline.
目的根据具有趋骨性的化合物的共同特征，设计并合成苯并吡喃4酮类化合物，检测它们的趋骨性。
Aim to design and synthesize benzopyran-4-one derivatives according to the common structural properties of compounds which have bone affinity and test their bone affinity.
结论骨靶向药物和载体具备低毒、稳定、趋骨性强等特点，能够直接到达病变部位发挥药效，具有很好的开发前景和临床应用价值。
Conclusion Bone-targeting drugs and carriers with low toxicity, high stability and strong bone affinity are valuable to be exploited and applied.
目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE To study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation.
目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE to study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation. METHODS Inhibitory zone diameter was measured by disc AGAR diffusion (DAD).
目的检测四环素类似物的体外抗菌活性，以观察类似物的抗菌和趋骨活性的相关性。
OBJECTIVE to study antibacterial activity in vitro and bone-affinity of tetracycline analogues to observe their correlation. METHODS Inhibitory zone diameter was measured by disc AGAR diffusion (DAD).
应用推荐