PF4属于造血负性调控因子，它抑制造血细胞增殖，但是它的这种作用是可逆的。
PF4 is a negative regulator of hematopoiesis and can inhibit hematopoietic cell proliferation but this effect is reversible.
结果多种致热性细胞因子和负调节介质共同作用，使机体温核集团对致热原作用发生指向性调控。
Pyrexia is an effect due to pyretic cytokine and negatively regulating factors, the reaction is about the regulatory increasing of temperature caused by the response of pyrogen from the body.
PF 4是造血负性调控因子，它是血细胞生成的抑制剂，特别是对巨核细胞的生成。
PF4 can inhibit newborn blood vessel production and is a negative regulator of hematopoiesis.
目前对saa病因的研究热点主要集中在t细胞亚群的异常、负性调控因子水平的改变、细胞凋亡等，现就这些方面的研究进行综述。
At present the cause of the SAA research focus mainly concentrated in the abnormal t cell subsets, a negative regulator of level changes and apoptosis, are reviewed on research in these areas.
目前对saa病因的研究热点主要集中在t细胞亚群的异常、负性调控因子水平的改变、细胞凋亡等，现就这些方面的研究进行综述。
At present the cause of the SAA research focus mainly concentrated in the abnormal t cell subsets, a negative regulator of level changes and apoptosis, are reviewed on research in these areas.
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