• 例如糖皮质激素受体基因大脑特定区域持续表达提高了调节应激反应能力

    For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.

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  • 受体家族经典作用机制配基存在下结合基因应答元件,从而在转录水平上调节基因表达

    The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.

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  • HR蛋白细胞核受体阻遏物发现证明HR蛋白是通过毛发周期调节基因表达来发挥作用的。

    The discovery that the HR protein is a nuclear receptor corepressor indicated that HR function in hair cycling is by regulating gene expression.

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  • 目的通过调节辣椒受体1 (VR1)基因表达VR 1基因功能疼痛基因治疗进行基础研究

    Objective: By regulation of VR1 gene expression, fundamentally investigate function of VR1gene and pains gene therapy.

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  • 这个变异称为IVS5-13insC,造成HMGA1蛋白功能损伤,HMGA1蛋白是调节胰岛素受体基因INSR表达辅助因子。

    The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.

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  • 这个变异称为IVS5-13insC,造成HMGA1蛋白功能损伤,HMGA1蛋白是调节胰岛素受体基因INSR表达辅助因子。

    The variant, designated IVS5-13insC, impairs function of the HMGA1 protein, a cofactor for gene activation that regulates insulin-receptor gene (INSR) expression.

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