诱导多能干细胞的医学应用的质疑。
Medical applications of induced pluripotent stem cells called into question.
解决此问题可借助于诱导多能干细胞，或称iPS。
A way around the problem is something called an induced pluripotent stem cell, or iPS.
源于自体的诱导多能干细胞通常被认为是没有免疫排斥问题的。
Whereas it has been generally assumed that these autologous cells should be immune-tolerated by the recipient from whom the iPSCs are derived, their immunogenicity has not been vigorously examined.
更加迫在眉睫的问题与控制原始捐赠和源于诱导多能干细胞的组织培养有关。
More immediate concerns have to do with control of the original donation and tissue grown from iPS cells.
新型合作关系会认可细胞提供者和实验人员双方对于培养和维持诱导多能干细胞的贡献。
New partnerships could acknowledge the contributions of both the cell provider and the laboratories that grow and sustain ips cell lines.
在基因表达控制有关的外在因素中，诱导多能干细胞与起源细胞间有着高度的相似性。
There were also significant similarities between iPSCs and cells of origin in factors related to the epigenetic control of gene expression.
而且，重组细胞表现出诱导多能干细胞的特征；这些细胞可以自我复制也可以分化为多种类型的细胞。
Still, the reprogrammed cells showed the defining characteristics of induced pluripotent stem cells; they could both differentiate into various cell types and generate more of themselves.
我们必须要认识到，诱导多能干细胞技术涉及到所有相关的复杂问题，并且游离于现存的法律和政策之外。
"We have to recognize all the complicated issues that iPS research is engaging and get a sense of how existing laws and policies play out," Caulfield said.
我们必须要认识到，诱导多能干细胞技术涉及到所有相关的复杂问题，并且游离于现存的法律和政策之外。
“We have to recognize all the complicated issues that iPS research is engaging and get a sense of how existing laws and policies play out, ” Caulfield said.
在生育门诊，诱导多能干细胞能使家长选择符合他们要求的胚胎，而在饱受争议的辅助生育技术下，这么做并不容易。
In fertility clinics, iPS cells could enable prospective parents to choose embryos for desired traits more easily than they can with conventional assisted-reproduction technologies.
已有一些证据证实诱导多能干细胞在基因表达方面，并不与胚胎干细胞完全相同，它仍保留有其来源组织的一些细胞记忆。
And there is some evidence that iPS cells aren't exactly like embryonic stem cells in their gene expression, retaining a subtle cellular memory of the tissue they came from.
为了证明是否捐赠的细胞基因表达类型确实持续存在，麻省研究小组对诱导多能干细胞基因型一致的大鼠细胞进行了研究。
To discover whether donor cell patterns of gene expression truly persisted, the MGH team studied cells from genetically identical mice originally generated from iPSCs.
然而令Loring惊喜的是，相应的人类基因确实能把这两种动物的细胞转换成称为诱导多能干细胞(iPS细胞)的类胚胎干细胞。
To Loring's surprise, however, the corresponding human genes did transform both animals' cells into embryonic-like stem cells called induced pluripotent stem cells (iPS cells).
对不同种类动物的诱导多能干细胞研究时发现，不同细胞起源引起的诱导多能干细胞差异大于不同动物种类引起的诱导多能干细胞差异。
Examining iPSCs generated from different animals revealed that differences based on the cell of origin were even greater than differences based on the animal of origin.
欧卡农教授告诉法新社，他们研究小组早起也曾用帮助一只小鼠恢复其活动能力，与注射所谓的诱导多能干细胞进入高位截瘫的猿猴的治疗方法类似。
Okano's research team, which earlier helped a mouse recover its mobility in a similar treatment, injected so-called induced pluripotent stem (iPS) cells into a paralyzed marmoset, he said.
这些发现说明，相对于胚胎干细胞的后代，从诱导多能干细胞分化来的某些细胞中异常的基因表达会在同基因的受体身上引起T细胞依赖的免疫反应。
These findings indicate that, in contrast to derivatives of ESCs, abnormal gene expression in some cells differentiated from iPSCs can induce T-cell-dependent immune response in syngeneic recipients.
同时，波士顿儿童医院的科研人员也做了相似的研究，研究结果已在《自然》杂志上发表。他们认为，细胞的记忆确实影响诱导多能干细胞的分化能力。
A similar study from researchers at Children's Hospital Boston, published simultaneously in the journal Nature, also finds that cellular "memory" affects the differentiation potential of iPSCs.
一些道德家建议说，组织捐赠者应保留这样的权利，即能够分享诱导多能干细胞系作为疾病模型，药物测试平台以及治疗方案所带来的潜在的巨大商业利益。
Some ethicists suggest that tissue donors deserve a share of the tremendous commercial potential of iPS cell lines as disease models, drug-testing platforms or treatments.
在未来，人类男性诱导性多能干细胞可能在试管中产生卵母细胞。
In the future, it may also be possible to generate human oocytes from male iPS cells in vitro.
脂肪干细胞为多能干细胞，能在体外定向诱导分化为成骨细胞。
Adipose-derived stem cells are multipotential stem cell and can be induced to osteoblast in vitro.
科学家已经把来自猪的细胞诱导转变成了多能干细胞——这种细胞就像胚胎干细胞一样，有能力发育成身体中的任何类型的细胞。
Scientists have managed to induce cells from pigs to transform into pluripotent stem cells - cells that, like embryonic stem cells, are capable of developing into any type of cell in the body.
科学家已经把来自猪的细胞诱导转变成了多能干细胞——这种细胞就像胚胎干细胞一样，有能力发育成身体中的任何类型的细胞。
Scientists have managed to induce cells from pigs to transform into pluripotent stem cells - cells that, like embryonic stem cells, are capable of developing into any type of cell in the body.
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