本文重点介绍目前主要的诱导分化剂在临床上的应用。
This article emphatically introduces the clinical application of differentiation inducer.
本研究旨在探讨诱导分化剂与细胞毒化疗药抗胶质瘤的联合效应。
This study was designed to investigate anti tumor effects of differentiation inducing agent in combination with cytotoxic chemotherapeutic drug against glioma.
结论苯丁酸钠和其它诱导分化剂联合应用可能是部分血液肿瘤有效的诱导分化治疗方法。
Conclusion Phenylbutyrate combined with other differentiation agents may be an effective differentiation therapy in a proportion of hematological malignancies.
分化诱导剂被广泛应用于肿瘤的研究，在肿瘤的预防和治疗方面取得一定的进展，其中以维甲酸类药物效果肯定。
Agents that induce cell differentiation have been widely used in tumor research and achieved progress in the prevention and treatment of tumor. among them, retinoid drug shows confirmative effect.
通过诱导芽分化和诱导愈伤两种途径，研究不同植物生长调节剂及浓度，对外植体萌发和生根的影响。
By the two pathway of inducing bud differentiation and wound, study on different plant growth regulator and concentration affect germination of explant and root.
中药在诱导干细胞分化为心肌细胞方面的研究较新，随着研究深入，将会有越来越多的中药诱导剂被发现。
It is new for traditional Chinese medicine to induce stem cell differentiation into cardiomyocytes. With deep research, more and more traditional Chinese medicine inducer will be found.
目的：临床试验中对组蛋白脱乙酰基酶阻滞剂(HDACi)的研究目的在于诱导细胞分化，生长停止，和肿瘤细胞的凋亡。
Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.
结论：APS有可能成为既能促进正常造血，又能抑制白血病等肿瘤细胞增殖，并诱导其凋亡或分化的天然诱导剂。
Conclusion: APS may not only promote normal hematopoiesis, but also inhibit the proliferation of leukemia cell and it can be a natural inducer for therapy of malignant tumor.
还对分化诱导剂、拓扑异构酶抑制剂、抗微管药和生物反应调节剂的筛选方法进行了评述。
In addition, the paper reviewed screening methods for differentiation inducers, DNA topoisomerase inhibitors, antimicrotubule drugs and biological response modifiers.
目的：研究肿瘤细胞分化诱导剂尿多酸肽(CDA - II)对人胃癌细胞的体外抑制作用。
Objective: to study the inhibitory effect of Uroacitide (CDA-II) on human gastric cancer cell in vitro.
目的探讨建立高效、快速分化诱导剂筛选模型。
Objective To establish a model for the rapid screening of differentiation-inducing agents.
结论：本法无需添加化学诱导剂，为一种简便、经济的诱导体外培养小鼠es细胞分化为心肌细胞的方法。
CONCLUSION: a simple and economical method was established to induce mouse es cells cultured in vitro to differentiate into cardiomyocytes without using any chemical reagents.
诱导分化是指在分化诱导剂的存在下，恶性肿瘤细胞的形态、生物学或生物化学方面的诸多标志均向正常细胞的方向分化，甚至完全转变成正常细胞。
By derived differentiation, we mean that under the effect of differentiation inducer, malignant tumor cell has the tendency to differentiate to normal cell, even became normal cells.
结论：釉基质蛋白可作为一种成骨诱导剂，能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
结果表明川芎嗪能定向诱导小鼠骨髓间充质干细胞分化为神经元样细胞，是较理想的诱导剂。
These results suggested that the mouse bone marrow-derived mesenchymal stem cells could be differentiated into neuron-like cells in vitro with the induction of tetramethylpyrazine.
结果表明川芎嗪能定向诱导小鼠骨髓间充质干细胞分化为神经元样细胞，是较理想的诱导剂。
These results suggested that the mouse bone marrow-derived mesenchymal stem cells could be differentiated into neuron-like cells in vitro with the induction of tetramethylpyrazine.
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