• 结论蛋白106- 126肽段能够诱导分化后的PC 12细胞凋亡具有明确毒性作用

    Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.

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  • 结论:普乐林具有诱导HL - 60细胞分化凋亡的双重作用

    Conclusion PR exerts effect on differentiation and induces apoptosis in HL-60 cells.

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  • 结论HMBAHL60细胞作用主要促进分化诱导凋亡不是主要作用机制;

    Conclusion: Inducing differentiation is the primary effect of HMBA on HL60 cells, and inducing apoptosis is not.

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  • 目的研究蛞蝓粗提体外培养肺癌细胞H 14抑制以及诱导分化凋亡作用

    Objective: to study the inhibitive effect of Limax extract on H14 and inducement effect of apoptosis and differentiation of H14 cells in vitro.

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  • 结论ATRA并不能诱导HL-60细胞完成终端分化但是该药可以诱导白血病细胞向成熟方向分化而且分化的肿瘤细胞发生凋亡

    CONCLUSION: ATRA cannot induce HL 60 to achieve terminal differentiation, but the differentiation of HL 60 can be induced by ATRA and the differentiated leukemia cells are easy to apoptosis.

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  • 结论APS可能成为促进正常造血能抑制白血病等肿瘤细胞增殖诱导凋亡分化天然诱导剂。

    Conclusion: APS may not only promote normal hematopoiesis, but also inhibit the proliferation of leukemia cell and it can be a natural inducer for therapy of malignant tumor.

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  • 结论JWA基因实现ATRATPA诱导白血病细胞分化凋亡可能具有双重调节作用

    It is concluded that JWA may play double important roles in regulating ATRA and TPA-induced differentiation and apoptosis in leukemic cells.

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  • 近年来,出现了诱导分化凋亡治疗手段,在某些肿瘤治疗上取得了可喜效果

    Recently, leading differentiation and apoptosis were found, and of a few clinical practice had proved their effect.

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  • 目的临床试验组蛋白脱乙酰基酶阻滞剂(HDACi)研究目的在于诱导细胞分化生长停止肿瘤细胞凋亡

    Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.

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  • 结论苯丁酸钠明显抑制C6细胞增殖诱导细胞分化甚至诱发细胞凋亡

    Conclusions SPB can apparently inhibit the proliferation of C6 cells and can induce cell differentiation and even apoptosis of C6 cells.

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  • 结论:蟾蜍灵抑制nb 4细胞活力及诱导细胞发生凋亡,蟾蜍灵atra联合应用显著增强A TRA对NB 4细胞的诱导分化作用

    Conclusion the combination of ATRA with bufalin can significantly enhance the differentiation of NB4 cells in vitro culture by ATRA.

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  • 方法:分别NBT还原分析DNA电泳分析观察药物诱导分化凋亡作用;

    METHODS: NBT dye reduction ability was used as the biomarker of differentiation of NB4 cells. Apoptosis was assayed through genomic DNA gel electrophoresis.

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  • 吡格列酮还显著减轻PAN诱导细胞凋亡坏死恢复足细胞的分化功能

    Further, pioglitazone significantly decreased PAN-induced podocyte apoptosis and necrosis while restoring podocyte differentiation.

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  • 吡格列酮还显著减轻PAN诱导细胞凋亡坏死恢复足细胞的分化功能

    Further, pioglitazone significantly decreased PAN-induced podocyte apoptosis and necrosis while restoring podocyte differentiation.

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