综述了喜树碱及其衍生物的小分子、大分子和轭合物前药的研究进展,为新型喜树碱前药的合理药物设计提供一定参考。
The recent progress in low molecular, high molecular and couplet prodrugs of CPTs was reviewed in classified manner, provide a reference for the design of prodrugs of CPTs.
本文主要综述了基于特定分子设计的有机大分子导向下的无机纳米粒子的分级有序自组装。
The hierarchical self-assembly of inorganic nanoparticles mediated by the tailed organic macromolecules has been reviewed.
对大分子前药的设计与合成,载体、活性药物和连接基的选择进行了论述。
The design and synthesis of macromolecular prodrugs, choice of polymer carrier, active drug and linker are introduced.
[摘要]研究人员描述了一种用来设计蛋白的计算方法,蛋白设计物能结合到大分子标的物表面上一个区域。
We describe a general computational method for designing proteins that bind a surface patch of interest on a target macromolecule.
设计将扭曲、非共平面的杂萘联苯结构引入聚芳酰胺亚胺的大分子主链,获得了耐高温、可溶解的新型聚芳酰胺亚胺。
A series of new aromatic poly(amide imide)s PI-P IV containing phthalazinone moieties are synthesized from the novel diamines I - IV by direct Yamazaki polycondensation.
设计将扭曲、非共平面的杂萘联苯结构引入聚芳酰胺亚胺的大分子主链,获得了耐高温、可溶解的新型聚芳酰胺亚胺。
A series of new aromatic poly(amide imide)s PI-P IV containing phthalazinone moieties are synthesized from the novel diamines I - IV by direct Yamazaki polycondensation.
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