这是《计算生物学组》的网站。
生物信息学和计算生物学研究领域。
概论1：课程概论及计算生物学计算方面的简介。
Intro 1: Course overview and introduction to the computational side of computational biology.
蛋白质结构预测问题是计算生物学领域的核心问题之一。
Protein structure prediction has proven to be one of the central problems in the field of computational biology.
这是宾夕法尼亚大学计算生物学和信息学实验室的网站。
This is a web site of Computational Biology and Informatics Laboratory at University of Pennsylvania.
我们介绍的溶解酵素模型只能将分子从新的计算生物学领域分离出来。
The lysozyme model we describe only scratches a molecule off the surface of the new field of computational biology.
在计算生物学中，常采用离散傅立叶变换进行频谱分析。
It can be taken as a kind of discrete signal and do spectrum analysis by discrete Fourier transform.
下面的示例是一个字符串算法，与计算生物学中经常使用的算法相似。
The next example is a string algorithm, like those commonly used in computational biology.
有向基因组移位排序问题在计算生物学研究中占有重要位置。
Sorting genomes by translocations plays an important role in computational biology.
在计算生物学中的一个很重要的问题是如何自动地进行这个分类过程。
One of the most important problems in computational biology is how to automate this classification procedure.
他的公式发表在刚刚出版的“公共科学图书馆计算生物学”期刊上的一篇8页长的科学论文里。
His formula occupies eight pages in a scientific paper just published in a journal called Public Library of Science (PLoS) Computational Biology.
基因组重组是计算生物学的一个重要研究领域，是基因组在基因水平比较分析的基础。
Genome rearrangement is an important area of computational biology, and bases the comparison analysis of genomes at the level of genes.
这可以简单到检查已刊出文章中的表格，或是复杂到提出新的计算生物学算法及相关图形。
This can be as simple as checking a table in a published article or as complex as a new computational-biology algorithm and associated graphics.
在查克拉瓦蒂。堪德瑞，赫尔辛基大学计算生物学研究员的研究中，参与者被分成两个焦点小组。
In a study done by Chakravarthi Kanduri, Computational Biology Researcher at the University of Helsinki, participants were split into two focus groups.
他从1994年开始从事计算生物学的研究，兴趣主要集中在如何将机器学习应用于多维生物学数据的理解。
He has worked on computational biology problems since 1994, concentrating on machine learning applications in understanding multidimensional biological data.
而该研究所的主要研究项目有哺乳动物基因收集、遗传变异、基因组信息学和计算生物学、基因组技术等等方面。
And the main research programs of the institute include mammalian gene collection, genetic variation, genome informatics and computational biology, genome technology and so on.
比较基因组学的方法：基因组对应、基因识别和调控特征序列的发现〉。 《计算生物学杂志》，11卷， 第2-3期（2004年）： 319-55页。
Kellis, M. , et al. "Methods in comparative genomics: genome correspondence, gene identification and regulatory motif discovery. " Journal of Computational Biology 11, no. 2-3 (2004): 319-55.
该行业的传统模型主要基于化学和基础生物学，但如今正让道给基于生物技术、计算、高级化学以及将三者综合的新方法。
The industry's traditional model, based chiefly on chemistry and basic biology, is giving way to a new approach based on biotechnology, computing, advanced chemistry and combinations of the three.
很多这些过去的计算方法都是去利用一些已经知道几十年甚至几百年的生物学概念。
Many of these past computational approaches sought to apply biological ideas that had been known for decades or centuries.
说实话，在计算机科学的一些主要分支学科的命名上就可以看出生物学的影子，譬如人工神经网络，遗传算法和进化计算法等等。
Indeed, the names of major subfields of computer science-such as artificial neural networks, genetic algorithms, and evolutionary computation-attest to the influence of biological analogies.
有人认为，生物学与计算机不同，它更复杂也更困难，因为需要实验室的参与。
Some have argued that biology is different from computing in that it is more complicated and harder to do because lab work is involved.
首先看看他的成就：他发明了一项叫做聚合酶链式反应的技术，这项技术对于生物学的意义就如同晶体管对于计算机的意义。
First his accomplishments: he invented a process called PCR, which is every bit as important to biology as the transistor is to computers.
就像他们生物学中的同名物一样，计算机病毒复制时就是将自己俯身于宿主上（一个程序或是计算机），然后利用宿主的资源来复制自己。
Like their biological namesakes, computer viruses replicate by attaching themselves to a host (a program, or a computer) and coopting the host's resources to copy themselves.
计算系统生物学的一个早期的成功故事是在细胞周期调控上所做的工作。
One of the early success stories of computational systems biology was the work done on cell-cycle regulation.
植物能够对光照做生物学‘计算’，利用光照的信息来建立自身防御系统抵抗当季的流行疾病。
So the plants perform a sort of biological light computation, using information contained in the light to immunize themselves against diseases that are prevalent during that season.
药物小分子合成；计算机辅助药物设计；化学生物学。
Structure-based drug molecule design and organic synthesis; Chemical biology.
药物小分子合成；计算机辅助药物设计；化学生物学。
Structure-based drug molecule design and organic synthesis; Chemical biology.
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