单侧微注射氟西泮可降低大鼠平均膈肌活动。
Unilateral microinjection of flurazepam in nucleus tractus so-litarius (NTS) depressed the average phrenic activity.
目的研究苯二氮牻类药物奥沙西泮的降解产物。
目的 建立血、尿中硝西泮的代谢物 7-氨基硝西泮GC-ECD检测方法。
OBJECTIVE To determine the contents of 7-aminonitrazepam, the metabolite of nitrazepam in plasma and urine by GC-ECD.
结论该化合物为奥沙西泮的降解产物,在国内首次报道,为《中国药典》中奥沙西泮的质量标准提高提供了科学依据。
CONCLUSION the compound was reported in domestic literature for the first time, providing reference for the improvement of oxazepam standard of Chinese pharmacopoeia.
目的通过测定大鼠对氟西泮抗痫耐受性和依赖性时海马中一氧化氮合酶(NOS)蛋白表达及活性的变化,探讨一氧化氮(NO)在此过程中可能的作用。方法建立大鼠对氟西泮抗痫耐受性和依赖性的模型。
Aim To study the role of nitric oxide by measuring the expression and activity of nitric oxide synthase in hippocampus of rats tolerance and dependence to the anticonvulsant action of flurazepam.
目的通过测定大鼠对氟西泮抗痫耐受性和依赖性时海马中一氧化氮合酶(NOS)蛋白表达及活性的变化,探讨一氧化氮(NO)在此过程中可能的作用。方法建立大鼠对氟西泮抗痫耐受性和依赖性的模型。
Aim To study the role of nitric oxide by measuring the expression and activity of nitric oxide synthase in hippocampus of rats tolerance and dependence to the anticonvulsant action of flurazepam.
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