组蛋白赖氨酸的甲基化在真核基因表观遗传调控中起着关键作用。
Histone lysine methylation plays a key role in epigenetic regulation of eukaryotic genes.
表观遗传调控可以影响基因转录活性而不涉及DNA序列的改变。
An epigenetic event alters the activity of genes without changing their structure.
我们将研究在体细胞重编程过程中的转录调控和表观遗传调控机制。
We are eager to explore the underlying transcriptional and epigenetic mechanisms of somatic cell reprogramming.
这些修饰调控组蛋白- DNA相互作用，为核小体迁移的表观遗传调控添加了新的维度。
These modifications regulate histone-DNA interactions, adding a new dimension to the epigenetic regulation of nucleosome mobility.
这种独一无二的特性受到来自于转录因子和表观遗传调控因子二者间复杂相互作用的调控。
This unique property is controlled by a complex interplay between transcriptional factors and epigenetic regulators.
在这里我们已经建立了SUMO结合的新角色，在表观遗传调控中调控的蛋白质和蛋白质甲基化。
Here we've established a new role for SUMOylation, mediating the interaction between protein and protein methylation in epigenetic regulation.
在DNA甲基化的胞嘧啶碱基在许多真核生物的表观遗传调控提供了一层正常的生物学和疾病有着重要的意义。
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease.
以酵母为模式生物，利用表观遗传，分子遗传和生物化学等手段，研究表观遗传调控在维持基因组稳定性中的作用。
Using yeast as model organism, study the contribution of epigenetic regulation to the maintenance of genomic stability, by epigenetic, molecular genetic and biochemic approaches.
2007年的试验结果令人眼界大开：染色体上藏着许多以前不为人知的位点，那里结合着各种各样的蛋白——可能是基因调控和表观遗传效应的温床。
The 2007 pilot results were eye-opening: Chromosomes harbored many previously unsuspected sites where various proteins bound—possible hotbeds of gene regulation or epigenetic effects.
这是基因调控是由控制基因的表观遗传完成的，并没有改变dna。
This gene regulation is accomplished by epigenetic processes that control gene expression without altering DNA.
表观遗传学是研究基因调控。
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白赖氨酸甲基化在基因表达调控中的作用已成为表观遗传学研究的热点。
The role of histone lysine methylation in the gene expression regulation has turned into the hotspot of epigenetics.
与此同时，越来越多的研究表明，对于肿瘤干细胞的发生与功能维持，表观遗传学的调控机制可能发挥着极其重要的作用。
At the same time, more and more studies have suggested that epigenetic regulation may play important roles in cancer stem cell development.
已知表观遗传过程，例如DNA甲基化调控组织特异基因表达。
Epigenetic processes, such as DNA methylation, are known to regulate tissue specific gene expression.
通过回顾重编程的研究进展来探讨表观遗传学在重编程中的调控机制。
Here we reviewed the research process in reprogramming to explore how epigenetic works in the reprogramming.
炎症反应中t辅助细胞的分化，细胞因子、趋化因子等基因的表达都受到表观遗传的调控。
In inflammation responses, differentiation of t helper cells and gene expression of cytokine and chemokine are all regulated by epigenetics.
炎症反应中t辅助细胞的分化，细胞因子、趋化因子等基因的表达都受到表观遗传的调控。
In inflammation responses, differentiation of t helper cells and gene expression of cytokine and chemokine are all regulated by epigenetics.
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