目的:提高临床对血药浓度监测工作的重视程度。
OBJECTIVE:To promote the attention on the blood concentration monitoring in clinical.
目的:探讨血药浓度监测对个体化、合理化用药的重要作用。
Objective to discuss the importance of blood concentration monitoring in more individualized and rationalized administration of Digoxin.
那是否需要对其进行常规的血药浓度监测?如何纠正其毒副反应。
Is it necessary to routinely test magnesium concentration and if toxicity occurs how should it be treated?
本方法准确快速,适用于加替沙星的药动学研究及临床血药浓度监测。
The method is accurate and rapid. It can be used to study pharmacokinetics of gatifloxacin mesylate and to monitor the plasma drug concentration.
其他设有临床药学室、血药浓度监测室、药学讯息资料室、药剂实验室等。
Besides, we also have clinical pharmacy department, blood concentration determination department, pharmaceutical information reference room, pharmaceutical laboratory.
因此,5-FU血药浓度监测和毒副反应严重程度的预测具有重要的临床意义。
So monitoring serum concentration and predicting toxicity of 5-FU mean clinical sense.
结论:本方法灵敏、准确、简单、快速,可用于临床血药浓度监测和药动学研究。
CONCLUSION: This method is sensitive, accurate, simple and fast, which can be used as the clinical monitoring of blood concentration of cilostazol and its pharmacokinetics study.
方法:以荧光偏振免疫法(FP IA)对194例癫痫患儿进行血药浓度监测。
Method: The serum concentrations of 194 children with epilepsy was monitored by fluorescence polarization immunoassay (FPIA).
结论该方法操作简便、快速、准确、稳定,可用于临床病人霉酚酸血药浓度监测。
Conclusion Homogeneous phase enzyme immunoassay is a simple, accurate and stable method for monitoring the MPA level in blood of patients in clinical practice.
方法对156例接受丙戊酸单药或联合用药治疗的门诊癫痫患者进行血药浓度监测。
METHODS 156 epileptic outpatients received valproic acid as monopharmacy or in combination with either the antiepileptic drug were monitored during their clinical routine care.
方法对2007年及2008年的血药浓度监测中随行质控样本测定值进行统计学分析。
Methods Statistical analysis was conducted on Digoxin control data determined together with the patient samples of 2007 and 2008.
排泄延迟更易出现于使用高剂量药物时。在血药浓度监测下使用大剂量MTX安全可行。
Application of high-dose MTX therapy under the monitoring of blood MTX concentration is safe and feasible.
目的通过血药浓度监测了解常规应用抗癫药患者的血药浓度情况,为临床合理用药提供参考。
Objective To investigate the situation in the clinical use of antiepileptic drugs(AEDS) so as to rationalize their clinical use.
目的:通过血药浓度监测,提高对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗的有效性和安全性。
OBJECTIVE: to improve the efficacy and safety of high dose methotrexate (HDMTX) chemotherapy in the treatment of children with acute lymphoblastic leukemia through blood concentration monitoring.
结论:可以通过血药浓度监测结果及临床观察相结合作为新生儿破伤风治疗过程中地西泮加减剂量的主要依据。
Conclusions: in therapy of neonatal tetanus, the dosage of diazepam should be increased or decreased according to the monitoring result of blood concentration and clinical observation.
目的:通过对90例氨茶碱血药浓度监测结果的分析,提出个体化给药建议,使氨茶碱在临床上使用更安全有效。
Objective: To put forward individual dose proposal by the analysis on blood drug concentration of Aminophylline of 90 cases for its safe and efficient clinical usage.
方法:利用荧光偏振免疫分析法(FPIA)对135例癫痫病人进行PB血药浓度监测,并对测定结果进行分析。
Methods: 135 epilepsy patients were monitored the PB blood concentrations by FPIA method and the result were analyzed.
结论:进行甲氨蝶呤血药浓度监测有利于掌握好甲氨蝶呤和四氢叶酸钙的救援剂量,从而保证化疗的有效性和安全性。
CONCLUSIONS: MTX serum concentration monitoring is helpful for mastering the rational rescue dosage of MTX and calcium folinate so as to ensure the efficacy and safety of the chemotherapy.
结论老年心衰病人的个体药代动力学参数波动范围大,个体差异更为突出,临床应在血药浓度监测的基础上实行最佳个体化给药。
Conclusions there is a significant individual variation in the pharmacokinetic parameters, therefore, the dose should be individualized on the basis of blood drug concentration monitoring.
结论HPLC - ECD测定血浆丙泊酚浓度,方法较简便、准确,灵敏度高,重现性好,适用于临床丙泊酚血药浓度监测及药动学研究。
CONCLUSION HPLC-ECD is rapid, simple, accurate and sensitive to determine propofol concentration in plasma. It is suitable for monitoring propofol and pharmacokinetic study.
方法:采用荧光偏振免疫法对2 6例服用苯妥英钠、74例服用卡马西平、14 4例服用丙戊酸钠的患者血药浓度监测结果及临床疗效分析、评价。
Method: The serum concentration of oral phenytoin, carbamazepine and valproic acid were determined in 26,74 and 144 epileptic patients by fluorescence polarization immunoassay, respectively.
因此,监测他克莫司血药浓度非常重要,因为可判断临床疗效、避免毒副作用。
Hence, it is of the utmost importance to monitor tacrolimus blood concentration, thereby ensuring clinical effect and avoiding toxic side effects.
结论:本方法简便快速、定量准确,可用于MMF临床药动学研究,也可用于mpa血药浓度的常规监测。
Conclusion: This method is simple, quick, accurate and can be used for the monitoring of the plasma concentration of MPA routinely and for the study on the clinical pharmacokinetics of MMF.
结论监测血药浓度,及时调整给药剂量,对控制儿童患者癫痫失神发作至关重要。
Conclusions Monitoring serum concentration and adjusting drug dosage in time are very important for controlling petit mal in children with epilepsy.
目的:采用反相高效液相色谱法测定两性霉素B的血药浓度,用于该药的治疗药物监测。
OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.
结论:在丙戊酸治疗药物监测中,要关注影响丙戊酸血药浓度的因素,确保患者用药安全有效。
CONCLUSION: in therapeutic drug monitoring of valproate, it should be concerned about the impact factors of valproate concentration to ensure the safety and efficacy in patients.
结论:胰肾移植术后应常规性的监测FK5 0 6血药浓度,随时调整其合理用量。
Conlution: After simultaneous pancreas kidney transplantation, the FK506 concentration in blood should be monitored on a routine basis and its dosage should be adjusted accordingly.
方法指导癫痫患者规律用药,并做好服药期间药物毒副反应的观察,定期监测血象、肝功能及血药浓度等。
Methods Epileptic patients were instructed to regularize dose, taking. Dosing side, effects were observed, and routine blood tests, liver function and drug concentration of serum were monitored.
结论:此方法简单、快速、准确,可用于药物中毒时的血药浓度分析及药物监测。
CONCLUSION: This method is simple, rapid, and accurate. It can be used in poison analysis and therapeutic drug monitoring.
在样品分析中,成功分离测定了注射药物的大鼠血浆中的布比卡因,实现了布比卡因血药浓度的快速监测。
When it was applied in sample analysis, bupivacaine was successfully separated and determined from the rat plasma after drug injection, and its concentration monitoring in plasma was carried out.
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