• 结论HPLC - ECD测定浓度,方法较简便准确灵敏度高,重现性好,适用于临床丙泊酚浓度监测动学研究

    CONCLUSION HPLC-ECD is rapid, simple, accurate and sensitive to determine propofol concentration in plasma. It is suitable for monitoring propofol and pharmacokinetic study.

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  • 目的测定国产进口拉西地平片剂浓度,进行动学参数比较

    OBJECTIVE: To determine the blood concentration of domestic and foreign lacidipine tablets, and compare their pharmacokinetic parameters.

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  • 结论:该法操作简便,结果可靠,适用于非诺贝特家兔血药浓度测定

    CONCLUSIONS This method is sensitive with constant result and rapid for determining fenofibric acid concentration in rabbits plasma.

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  • 克拉霉素浓度微生物进行测定

    The serum drug concentrations were measured by microbiological assay.

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  • 浓度采用高效液相色谱法测定

    Serum concentration of bifemelane was measured by HPLC.

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  • 采用HPLC MS法测定后不同时间红霉素红霉素浓度

    The concentrations of erythromycin propionate and erythromycin base in the plasma were determined by HPLC-MS.

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  • 方法2007年2008年血药浓度监测中随行质控样本测定进行统计学分析

    Methods Statistical analysis was conducted on Digoxin control data determined together with the patient samples of 2007 and 2008.

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  • 目的制备硝苯地平缓释片并测定释放度血药浓度

    OBJECTIVE: To prepare the long acting nifedipine tablet, determined dissolution rate and plasma concentration of nifedipine in dog.

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  • 药浓度采用微生物进行测定

    Plasma concentrations were measured by microbial method.

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  • 高效液相色谱法测定药浓度

    The blood concentrations were determined by HPLC.

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  • 目的建立西尼地平浓度液相色谱串联质LC-MS/MS)测定研究中国健康男性受试者口服西尼地平胶囊后动学特点。

    Objective:To establish a selective and sensitive LC-MS/MS method for the determination of cilnidipine in human plasma, and to study the pharmacokinetics in healthy volunteers.

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  • 方法利用荧光偏振免疫分析法(FPIA)对135癫痫病人进行PB浓度监测测定结果进行分析

    Methods: 135 epilepsy patients were monitored the PB blood concentrations by FPIA method and the result were analyzed.

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  • 采用HPLC测定中的浓度

    Drug concentrations in serum were assayed by HPLC.

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  • 方法采用原位,设计肠道冲洗实验,测定胰岛素肠道吸收效应药浓度

    Methods the intestinal absorption of insulin was evaluated by its hypoglycemic effect and serum insulin level using an in situ loop method with the washing treatment.

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  • 不同时间反相高效液相色谱测定吲哚美辛药浓度

    Then we collect the blood in different time point and assay the blood concentration of indomethacin by RP-HPLC.

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  • 目的研究HPLCFPIA两种方法测定英钠浓度相关性

    OBJECTIVE to study the relativity between serum phenytoin concentrations determined by HPLC and FPIA.

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  • 目的:采用高效液相色谱(hplc)测定硝苯地平临床治疗血药浓度

    Objective: to monitor the clinical therapeutic concentrations of nifedipine by HPLC method.

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  • 术后分时段动物浓度药浓度测定

    Then the drug concentrations were determined in blood and bone of animals at a series different time.

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  • 疗效不良反应分别简明精神病评定量表(BPRS)和副反应量表(TESS)进行评定,并测定治疗第1,2,4,6稳态药浓度

    Therapeutic efficacy was measured by BPRS and the adverse reaction was rated by TESS. Steady serum level was monitored within 1, 2, 4, 6 week.

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  • 采用HPLC-MS法测定奥曲肽血药浓度

    Octreotide concentration in plasma was detected by HPLC-MS.

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  • 方法:采用荧光偏振免疫法测定276癫痫患者丙戊酸药浓度分析结果

    METHODS: the serum concentrations of valproate in 276 patients were determined by fluorescence polarization immunoassay and the results were analyzed.

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  • 结果测定方法与给量相同情况下,肠溶片的血药浓度数据不完整

    RESULTS the concentrations were incomplete for enteric-coated Metformin Hydrochloride tablets after the same doses were administrated.

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  • 目的测定10个男性健康者11个时间盐酸雷尼替丁泡颗粒剂药浓度及其物动力学参数。

    OBJECTIVE: To determine serum concentration of ranitidine Hydrochloride Effervescent Granules in 10 normal male at 11 time points.

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  • 目的采用反相高效液相色谱法测定两性霉素B浓度,用于该治疗监测

    OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.

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  • 方法采取灌胃和外敷两种方式高效液相色谱法测定不同时项点浓度

    METHODS: Two ways of drug given intragastral and usum externum were adopted, and the blood concentration of tetrandrine was detected by high performance liquid chromatography.

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  • 结论:胶束电动毛细管电泳临床提供了一种高效快速测定浓度手段

    Thus monitoring of the drugs in human blood with electrokinetic capillary chromatography was demonstrated to be a new , rapid and highly efficient method for the clinical study.

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  • 方法18健康男性志愿者剂量口服盐酸帕罗西汀片,设计时间点取静脉血药浓度采用液相色谱质谱(HPLCMS测定

    METHODS A single oral dose of 40 mg paroxetine hydrochloride was given to 18 healthy volunteers. The concentrations of paroxetine in plasma were assayed by HPLC-MS method.

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  • 方法测定48女性癫痫病人prl水平同时监测药浓度了解生殖内分泌功能状况

    Methods We measured serum PRL levels in 48 female patients, and monitored the blood concentration of AEDs in order to know the state of reproductive endocrine functions.

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  • 采用高效液相色谱紫外检测法测定西沙必利血药浓度分析西沙必利致心律失常作用浓度相关性

    The HPLC method was used to determine the cisapride plasma concentration. Analyze the relationship between the effect of cisapride facilitating arrhythmia and its plasma concentration.

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  • 方法采用高效液相色谱法测定血药浓度

    METHODS The plasma levels were determined by HPLC.

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