结论HPLC - ECD测定血浆丙泊酚浓度,方法较简便、准确,灵敏度高,重现性好,适用于临床丙泊酚血药浓度监测及药动学研究。
CONCLUSION HPLC-ECD is rapid, simple, accurate and sensitive to determine propofol concentration in plasma. It is suitable for monitoring propofol and pharmacokinetic study.
目的:测定国产与进口拉西地平片剂的血药浓度,进行药动学参数比较。
OBJECTIVE: To determine the blood concentration of domestic and foreign lacidipine tablets, and compare their pharmacokinetic parameters.
结论:该法操作简便,结果可靠,适用于非诺贝特酸家兔血药浓度的测定。
CONCLUSIONS This method is sensitive with constant result and rapid for determining fenofibric acid concentration in rabbits plasma.
克拉霉素的血药浓度用微生物法进行测定。
The serum drug concentrations were measured by microbiological assay.
血药浓度采用高效液相色谱法测定。
采用HPLC MS法测定给药后不同时间丙酸红霉素和红霉素碱的血药浓度。
The concentrations of erythromycin propionate and erythromycin base in the plasma were determined by HPLC-MS.
方法对2007年及2008年的血药浓度监测中随行质控样本测定值进行统计学分析。
Methods Statistical analysis was conducted on Digoxin control data determined together with the patient samples of 2007 and 2008.
目的:制备硝苯地平缓释片并测定释放度和犬血药浓度。
OBJECTIVE: To prepare the long acting nifedipine tablet, determined dissolution rate and plasma concentration of nifedipine in dog.
血药浓度采用微生物法进行测定。
用高效液相色谱法测定血药浓度。
目的:建立西尼地平血药浓度的液相色谱串联质谱(LC-MS/MS)测定法,研究中国健康男性受试者口服西尼地平胶囊后的血浆药动学特点。
Objective:To establish a selective and sensitive LC-MS/MS method for the determination of cilnidipine in human plasma, and to study the pharmacokinetics in healthy volunteers.
方法:利用荧光偏振免疫分析法(FPIA)对135例癫痫病人进行PB血药浓度监测,并对测定结果进行分析。
Methods: 135 epilepsy patients were monitored the PB blood concentrations by FPIA method and the result were analyzed.
采用HPLC测定血清中的血药浓度。
方法采用原位肠袢法,设计肠道冲洗实验,测定胰岛素肠道吸收后的降血糖效应和血药浓度。
Methods the intestinal absorption of insulin was evaluated by its hypoglycemic effect and serum insulin level using an in situ loop method with the washing treatment.
于不同时间点取血,以反相高效液相色谱法测定吲哚美辛的血药浓度。
Then we collect the blood in different time point and assay the blood concentration of indomethacin by RP-HPLC.
目的研究用HPLC和FPIA两种方法测定苯妥英钠血药浓度的相关性。
OBJECTIVE to study the relativity between serum phenytoin concentrations determined by HPLC and FPIA.
目的:采用高效液相色谱(hplc)法测定硝苯地平临床治疗血药浓度。
Objective: to monitor the clinical therapeutic concentrations of nifedipine by HPLC method.
术后分时段对动物血药浓度和骨药浓度测定。
Then the drug concentrations were determined in blood and bone of animals at a series different time.
疗效和不良反应分别用简明精神病评定量表(BPRS)和副反应量表(TESS)进行评定,并测定治疗第1,2,4,6周的稳态血药浓度。
Therapeutic efficacy was measured by BPRS and the adverse reaction was rated by TESS. Steady serum level was monitored within 1, 2, 4, 6 week.
采用HPLC-MS法测定奥曲肽血药浓度。
方法:采用荧光偏振免疫法测定276例癫痫患者的丙戊酸血药浓度并分析结果。
METHODS: the serum concentrations of valproate in 276 patients were determined by fluorescence polarization immunoassay and the results were analyzed.
结果在测定方法与给药量相同的情况下,肠溶片的血药浓度数据不完整。
RESULTS the concentrations were incomplete for enteric-coated Metformin Hydrochloride tablets after the same doses were administrated.
目的:测定10个男性健康者11个时间点盐酸雷尼替丁泡腾颗粒剂的血药浓度及其药物动力学参数。
OBJECTIVE: To determine serum concentration of ranitidine Hydrochloride Effervescent Granules in 10 normal male at 11 time points.
目的:采用反相高效液相色谱法测定两性霉素B的血药浓度,用于该药的治疗药物监测。
OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.
方法:采取灌胃和外敷两种给药方式,高效液相色谱法测定不同时项点的血药浓度。
METHODS: Two ways of drug given intragastral and usum externum were adopted, and the blood concentration of tetrandrine was detected by high performance liquid chromatography.
结论:胶束电动毛细管电泳为临床提供了一种高效、快速测定血药浓度的新手段。
Thus monitoring of the drugs in human blood with electrokinetic capillary chromatography was demonstrated to be a new , rapid and highly efficient method for the clinical study.
方法18名健康男性志愿者,单剂量口服盐酸帕罗西汀片,在设计的时间点取静脉血,血药浓度采用液相色谱质谱(HPLCMS)法测定。
METHODS A single oral dose of 40 mg paroxetine hydrochloride was given to 18 healthy volunteers. The concentrations of paroxetine in plasma were assayed by HPLC-MS method.
方法测定48例女性癫痫病人血清prl水平,同时监测血药浓度及了解生殖内分泌功能状况。
Methods We measured serum PRL levels in 48 female patients, and monitored the blood concentration of AEDs in order to know the state of reproductive endocrine functions.
②采用高效液相色谱紫外检测法测定西沙必利血药浓度,分析西沙必利致心律失常作用与药物浓度相关性。
The HPLC method was used to determine the cisapride plasma concentration. Analyze the relationship between the effect of cisapride facilitating arrhythmia and its plasma concentration.
方法采用高效液相色谱法测定血药浓度。
应用推荐