第二阶段的成功治疗依赖于可穿过血脑屏障达到寄生虫的一种药物。
Treatment success in the second stage depends on a drug that can cross the blood-brain barrier to reach the parasite.
这主要是因为它是一种大分子物质，要穿过保护大脑免受血液中可能有害化合物入侵的血脑屏障很困难。
This is mainly because it is a large molecule, and has difficulty passing through the blood-brain barrier which protects the brain from potentially harmful compounds in the blood.
特布他林穿过胎盘屏障和胎儿的血脑屏障，可能导致自闭症系列障碍和其他精神障碍。
Terbutaline crosses the placental barrier and blood-brain barrier of the fetus, which may lead to an autistic-spectrum disorder and other developmental disorders.
和血脑屏障相同，它是选择性可透的，阻挡血液中的有害物质进入到精致的感光层。
Like the blood-brain barrier, this is only selectively permeable, keeping any toxins in the blood from reaching the delicate photoreceptors.
这是第一次有新的生物药剂能有效的通过血脑屏障，进入大脑。
It's the first time new 'biological' medicines have been delivered effectively across the blood-brain-barrier to the brain.
在第二阶段，寄生虫穿过血脑屏障感染中枢神经系统。
In the second stage the parasites cross the blood-brain barrier to infect the central nervous system.
我们用自然分类系统可发出了跨过血脑屏障的药物技术。
We’ve shown that a natural system could be exploited to deliver drugs across the blood-brain barrier.
我们用自然分类系统可发出了跨过血脑屏障的药物技术。
'We've shown that a natural system could be exploited to deliver drugs across the blood-brain barrier.
这将意味着，大脑疾病的治疗可以无需穿过血脑屏障，也无需与大脑接触。
This would mean that a condition that affects the brain could be treated with something that does not cross the blood-brain barrier and does not come into contact with the brain.
现在loannou实验室正在研究这种现象能够透过血脑屏障使脑细胞中的溶酶体释放溶菌酶去清除生理废物。
Now the Ioannou lab is studying whether this signal can also be transmitted across the blood-brain barrier to the lysosomes in brain cells to tell them to empty their stored waste products.
为此，Renslo博士与其同事已经在分析并尝试修饰氨噻唑的分子结构，以使之能通过血脑屏障。
Dr Renslo and his colleagues have therefore been analysing and modifying the chemical structure of aminothiazoles to see if this can enable them to cross the blood-brain barrier.
它具有优越的生物利用度和运输跨越血脑屏障进入细胞。
It has superior bioavailability and transports well across the blood brain barrier and into cells.
目的：研究脑创宁对闭合性脑外伤模型小鼠血脑屏障的保护作用。
Objective: To research the protective effects of Naochuangning on blood brain barrier in closed cerebral trauma mice.
但是喝红酒并不能增血糖和胰岛素的水平，因为白藜芦醇在脑中不能有效地通过血脑屏障。
But drinking red wine is not likely to improve blood sugar and insulin levels because resveratrol does not cross the blood-brain barrier very efficiently.
发现一种可以穿越血脑屏障的药物是阿尔茨海默氏病和其他脑部神经疾病药物研制中的障碍。
Finding a drug that can cross the blood-brain barrier is the bane of drug development for Alzheimer's disease and other neurological disorders of the brain.
在急性脑缺血的超早期，完整的血脑屏障(BBB)使许多治疗药物无法在有效治疗时间窗内进入脑组织发挥作用。
In the super early phase of acute cerebral ischemia, many therapeutic drugs cannot penetrate into the complete blood-brain barrier (BBB) and enter brain tissues within the effective time window.
尽管胆固醇整天被认为是个对人体有害的物质，但它却是脑的重要成分，是通过血脑屏障的常客。
That made the aminothiazoles look more like cholesterol—which despite its malign everyday reputation is an important component of brains and routinely crosses the blood-brain barrier.
结论高机械指数的体表超声辅以高剂量超声造影剂在经颅脑超声造影中可导致血脑屏障通透性增加，但在造影检查后，这种改变可自行恢复。
Conclusions the combine use of the high MI ultrasound and the high dosage of the ultrasound contrast agent can enhance the permeability of the BBB, but this change is reversible.
这是第一次有新的生物药剂能有效的通过血脑屏障，进入大脑。
'It's the first time new' biological 'medicines have been delivered effectively across the blood-brain-barrier to the brain.
垂体柄或漏斗与其它脑室周围器官一样有着血脑屏障外器官的特性。
This structure also known as the infundibulum is often grouped with other "circumventricular organs" which share the property of being outside the blood-brain-barrier.
目的制备盐酸他克林(THA)的酰化前体药物以提高其透过血脑屏障(BBB)的能力。
Aim to synthesize acylated prodrug of tacrine hydrochloride (THA) to improve the infiltration ability across the blood brain barrier (BBB).
结果（1）烧伤大鼠和NE刺激后的烧伤大鼠血脑屏障通透性增加，与对照组比较差异有统计学意义（P<0.01）。
Results (1) Permeability of blood brain barrier was increased in burn and burn with NE stimulating rats, with significantly statistical difference compared with normal control group (P<0.01).
目的：氟桂利嗪是通过血脑屏障的细胞钙超载阻滞剂。
AIM: Flunarizine is a blocker for calcium overload of cells, which could pass blood brain barrier.
结论在高原状态下去甲肾上腺素可使血脑屏障通透性显著增高，诱发高原脑水肿加重。
Conclusion It is suggested that noradrenalin may enhance the permeability of blood brain barrier and trigger the aggravation of high altitude cerebral edema.
结论再灌注损伤早期皮质神经元、胶质细胞、细胞骨架和血脑屏障即发生变化。
ConclusionCortical neurons, neuroglia cells, cytoskeleton and blood-brain barrier changed at early stage of reperfusion damage.
其中18例多发性硬化病人中，有7例出现寡克隆条带，2例出现血脑屏障受损。
Of 18 patients with multiple sclerosis, there were 7 patients displayed oligoclonal band and 2 patients presented blood-brain barrier impairment.
移植物内已建立了局部神经环路，血脑屏障已形成。
It had built local circuit and blood - brain barrier in the graft.
环氧化酶- 2 (COX - 2)及其代谢产物可通过对脉管系统、血脑屏障和神经元本身的损伤，参与脑缺血再灌流后损伤的机制。
Cyclooxygenase-2 (COX-2) and its metabolic products can be involved in the mechanism of the ischemic brain injury through destructing the vascular system, blood-brain barrier and the neuron.
环氧化酶- 2 (COX - 2)及其代谢产物可通过对脉管系统、血脑屏障和神经元本身的损伤，参与脑缺血再灌流后损伤的机制。
Cyclooxygenase-2 (COX-2) and its metabolic products can be involved in the mechanism of the ischemic brain injury through destructing the vascular system, blood-brain barrier and the neuron.
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