目的探讨凝血酶(TB)对血脑屏障通透性的影响及其可能机制。
Objective To explore the effect of thrombin (TB) on the blood brain barrier(BBB) permeability and its possible mechanism.
亚低温能有效抑制脑梗死后AQP4的表达和血脑屏障通透性的增加。
Mild hypothermia may relieve cerebral edema after cerebral infarct since it can inhibit AQP4 expressions and increase blood brain-barrier permeability.
前言:目的:考察脑创宁对闭合性脑外伤小鼠脑水肿、血脑屏障通透性的作用。
Objective: To research the effect of Naochuangning on cerebral edema and the permeability of blood brain barrier in closed cerebral trauma mice.
血脑屏障通透性增高是造成血管源性脑水肿和炎症反应等病理学变化的主要环节。
The increase of blood-brain barrier (BBB) permeability is a key link in causing the pathological changes in vasogenic brain edema and inflammatory reaction.
结论在高原状态下去甲肾上腺素可使血脑屏障通透性显著增高,诱发高原脑水肿加重。
Conclusion It is suggested that noradrenalin may enhance the permeability of blood brain barrier and trigger the aggravation of high altitude cerebral edema.
血红素氧合酶诱导剂、抑制剂对非梗塞侧的血脑屏障通透性没有影响(P>0.05)。
There was no significant changes in BBB permeability among hemin, ZnPP and saline groups in noninfarcted side(P>0.05).
目的:探讨机械性脑干损伤早期脑组织中一氧化氮含量和血脑屏障通透性的改变及其意义。
Objective: To study the significance of early changes of nitric oxide level in brain tissue and the permeability of blood brain barrier after mechanical injury in brainstem.
此外,根据线性溶剂化方程建立了定量结构-活性关系用于预测药物肠吸收、血脑屏障通透性和皮肤透过性。
Quantitative structure-activity relationships also have been established to predict drug intestinal absorption, permeation of skin and blood-brain barrier.
结果(1)烧伤大鼠和NE刺激后的烧伤大鼠血脑屏障通透性增加,与对照组比较差异有统计学意义(P<0.01)。
Results (1) Permeability of blood brain barrier was increased in burn and burn with NE stimulating rats, with significantly statistical difference compared with normal control group (P<0.01).
结论高机械指数的体表超声辅以高剂量超声造影剂在经颅脑超声造影中可导致血脑屏障通透性增加,但在造影检查后,这种改变可自行恢复。
Conclusions the combine use of the high MI ultrasound and the high dosage of the ultrasound contrast agent can enhance the permeability of the BBB, but this change is reversible.
酸枣仁汤能增加血液及脑组织NOS含量,促进NO的生成,提示其可能通过舒张毛细血管,增大血脑屏障通透性,从而提高酸枣仁汤对脑组织的作用。
And it could promote NO and NOS synthesis and secretion and might relax capillary vessel and raise the permeability of blood-brain barrier and enhance its effect on brain tissue.
结论冰片可提高血脑屏障对丙戊酸钠的通透性,但对血药浓度影响较小。
ConclusionBorneol can enhance the permeability of blood-brain barrier to sodium valproate, but has small influence on blood concentration.
目的探讨犬脑枪弹伤后血脑屏障(BBB)通透性改变及意义。
Objective To study the change in blood-brain barrier (BBB) permeability in dog with craniocerebral gunshot injury and its significance.
同时他还说:“这个研究结果强调了这样一个事实——血脑屏障的通透性改变是发生象实验性变应性脑脊髓炎(一种多发性硬化病的动物模型)这类中枢神经系统感染性疾病的重要因素。”
"This puts an emphasis on the fact that blood brain permeability changes are an important aspect of the development of a CNS inflammatory disease like EAE, an animal model of MS," he says.
用伊文思蓝测定血脑屏障的通透性。
The Evans blue EB was used to test the permeability of blood brain barrier BBB.
研究表明,当中枢神经系统遭受损伤或患某种急性疾病时,血脑屏障受到破坏或通透性发生改变,患者血清中MBP的含量明显增高。
Some researches have revealed the increase of serum MBP concentration in the patients suffered from trauma or acute disease of CNS, while the blood-spinal or blood-brain barrier was destructed.
结论黄体酮可以降低缺血再灌注大鼠脑组织AQP4的表达,从而降低血脑屏障的通透性,减轻脑水肿。
Conclusion Progesterone could alleviate cerebral edema via reducing permeability of blood brain barrier by the inhibition on protein expression of AQP4.
结论黄体酮可以降低缺血再灌注大鼠脑组织AQP4的表达,从而降低血脑屏障的通透性,减轻脑水肿。
Conclusion Progesterone could alleviate cerebral edema via reducing permeability of blood brain barrier by the inhibition on protein expression of AQP4.
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