尾池小组确认的新罪魁祸首是一种脂源性的蛋白，叫做血管生成素样蛋白2。
The new culprit Oike's team identifies is a fat-derived protein called angiopoietin-like protein 2 (Angptl2).
“在健康运物和人群中，血管生成素样蛋白2准确的作用没有被证实，”他说。
"In healthy animals and people, the precise role of Angptl2 has not been clarified, " he said.
在人体中也是，他们发现在高体重指数和胰岛素水平的人群中血管生成素样蛋白2水平更高。
In humans, too, they find higher Angptl2 levels in the blood of people with higher body mass index and insulin levels.
然而，先天血管生成素样蛋白2缺少的大鼠正常出生和正常生长，显示了和先天正常的大鼠一样。
However, mice in which Angptl2 was deleted genetically were born normally and showed normal growth compared to genetically normal mice.
尾池说他认为作用在血管生成素样蛋白2的药物不仅有很大的治疗前景，而且可能只有很少副作用。
Oike says he thinks drugs that would act on Angptl2 not only have considerable promise, but are also likely to come with limited side effects.
然而，我们推测严重不利的副作用发生的可能性，是由于减少在动物和人群中血管生成素样蛋白2表达的治疗水平太低了。
Therefore, we speculate that the possibility of the occurrence of a serious unfavorable side effect due to treatments that decrease Angptl2 expression in animals or people is low.
目的通过测定人血清血管生成素样蛋白3 (angiopioetin - like protein 3, ANGPTL3)的含量，探讨ANGPTL3表达量与代谢综合征(metabolic syndrome,MS)的关系。
Objectives To study the relationship between angiopioetin-like protein 3 (ANGPTL3) and Metabolic syndrome (MS) by measuring the serum level of ANGPTL3 in MS patients.
目的通过测定人血清血管生成素样蛋白3 (angiopioetin - like protein 3, ANGPTL3)的含量，探讨ANGPTL3表达量与代谢综合征(metabolic syndrome,MS)的关系。
Objectives To study the relationship between angiopioetin-like protein 3 (ANGPTL3) and Metabolic syndrome (MS) by measuring the serum level of ANGPTL3 in MS patients.
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