对血管生成素及其相关蛋白的研究进展和分子生物学特性进行了综述。
The advantages and progresses of investigations on angiopoietins, angiopoietin related proteins and their molecular and biological properties have been reviewed.
血管生成素的核糖核酸酶活性很弱，但对它的血管生成活性是至关重要的。
Although the catalytic activity of angiogenin is rather weak, it is critical for its angiogenic properties.
尾池小组确认的新罪魁祸首是一种脂源性的蛋白，叫做血管生成素样蛋白2。
The new culprit Oike's team identifies is a fat-derived protein called angiopoietin-like protein 2 (Angptl2).
“在健康运物和人群中，血管生成素样蛋白2准确的作用没有被证实，”他说。
"In healthy animals and people, the precise role of Angptl2 has not been clarified, " he said.
行免疫组化及RT - P CR检测腹膜组织血管生成素及其受体的表达变化。
Vessel density of the peritoneum was detected, and the expression levels of angiopoietin and its receptor were examined in the peritoneum by immunohistochemistry and RT-PCR.
血管生成素是近年研究较多的血管生成因子，在血管生成和稳定性的维持中起着重要作用。
Angiopoietin is an important angiogenic factor. It plays a crucial role in formation and stability maintenance of blood vessels.
在人体中也是，他们发现在高体重指数和胰岛素水平的人群中血管生成素样蛋白2水平更高。
In humans, too, they find higher Angptl2 levels in the blood of people with higher body mass index and insulin levels.
然而，先天血管生成素样蛋白2缺少的大鼠正常出生和正常生长，显示了和先天正常的大鼠一样。
However, mice in which Angptl2 was deleted genetically were born normally and showed normal growth compared to genetically normal mice.
血管发生在实体肿瘤及血液系统恶性肿瘤进程中扮演重要角色。血管生成素是其重要的调节因素。
Angiogenesis plays an important role in solid tumors and hematologic malignancies. The angiopoietins act as essential regulators in this process.
结论尿毒症本身及腹膜透析液均会上调腹膜的血管生成素及其受体表达，且与血管新生密切相关。
Conclusion Uremia itself and peritoneal dialysate up-regulate the expression of angiopoietin and its receptor. Angiopoietin and its receptor are closely related with the angiogenesis.
尾池说他认为作用在血管生成素样蛋白2的药物不仅有很大的治疗前景，而且可能只有很少副作用。
Oike says he thinks drugs that would act on Angptl2 not only have considerable promise, but are also likely to come with limited side effects.
人血管生成素-1基因的克隆及表达载体的构建，为进一步研究其功能、活性和应用奠定了基础。
The cloning of human angiopoietin 1 gene and construction of it's expression vectors lay a good foundation of further study on the function, biological activity and application.
血管生成素2，一种炎症时血管通透性的调节因子，与德美两国急性胰腺炎患者持续器官衰竭有关。
Angiopoietin-2, a Regulator of Vascular Permeability in Inflammation, is Associated With Persistent Organ Failure in Patients With Acute Pancreatitis From the United States and Germany.
血管生成素一2高表达和E一钙粘附蛋白低表达有可能作为筛查高侵袭性、高转移能力的肝癌亚型的指标。
The high expression of Angiopoietin-2 and low expression of E-Cadherin maybe be regarded as an index screening liver carcinoma of strongly potential invasion and high frequent metastasis.
目的：本研究拟探讨冠脉严重狭窄患者血清血管生成素-1，血管生成素-2浓度与冠脉侧支形成的关系。
Manys studies showed that angiopoietin-1(ANG-1) could stimulate coronary collateral artery formation and angiopoietin-2(ANG-2) might inhibit angiogenesis by inhibition of ANG-1.
然而，我们推测严重不利的副作用发生的可能性，是由于减少在动物和人群中血管生成素样蛋白2表达的治疗水平太低了。
Therefore, we speculate that the possibility of the occurrence of a serious unfavorable side effect due to treatments that decrease Angptl2 expression in animals or people is low.
目的通过测定人血清血管生成素样蛋白3 (angiopioetin - like protein 3, ANGPTL3)的含量，探讨ANGPTL3表达量与代谢综合征(metabolic syndrome,MS)的关系。
Objectives To study the relationship between angiopioetin-like protein 3 (ANGPTL3) and Metabolic syndrome (MS) by measuring the serum level of ANGPTL3 in MS patients.
其中用于提高耐力的主要有促红细胞生成素、血管内皮生长因子等，用于提高肌肉力量的有胰岛素样生长因子-I、肌肉生长抑制素、生长激素、机械生长因子等。
In those gene doping, EPO and VEGF are used to enhance the endurance performance; IGF-I, myostatin, GH and MGF are used to improve muscle strength.
其中用于提高耐力的主要有促红细胞生成素、血管内皮生长因子等，用于提高肌肉力量的有胰岛素样生长因子-I、肌肉生长抑制素、生长激素、机械生长因子等。
In those gene doping, EPO and VEGF are used to enhance the endurance performance; IGF-I, myostatin, GH and MGF are used to improve muscle strength.
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