目的:探讨CD 34在人鼻息肉组织中的表达及微血管密度的临床意义。
Objective: To study the clinicopathologic significance of microvessel density and the expression of CD34 in human nasal polyps.
胆囊结石,胆囊息肉,肝血管瘤。
Cholecystlithiasis, polyp of gallbladder, hemangioma of liver.
结果:血管内皮生长因子及其受体在正常鼻粘膜呈弱阳性,在鼻息肉呈强阳性表达。
Result: The expression of VEGF and VEGFR was weak in normal nasal mucous, and very strong in nasal polyps.
主要观察指标:鼻息肉组织和正常鼻黏膜组织血管内皮生长因子及其受体的表达。
MAIN OUTCOME MEASURES: The expression of VEGF and its receptors in polypous tissue and in normal nasal mucosa tissues.
VEGF在鼻息肉组织中主要定位于基底膜周围的炎性细胞和上皮细胞以及腺体、血管周围和血管壁内皮细胞。
VEGF is mainly located in the inflammatory cells and epithelial cells surrounding the basilar membrane and inflammatory cells and endothelial cells surrounding the vessels.
VEGF在鼻息肉组织中主要定位于基底膜周围的炎性细胞和上皮细胞以及腺体、血管周围和血管壁内皮细胞。
VEGF is mainly located in the inflammatory cells and epithelial cells surrounding the basilar membrane and inflammatory cells and endothelial cells surrounding the vessels.
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