采用高效液相色谱(HPLC)测定硬膜外给药后血浆药物浓度。
High performance liquid chromatography (HPLC) was used to measure the plasma concentrations of local anesthetics following epidural administration.
化合物b 5、D2和D6在脑中的药物浓度与同时间的血浆药物浓度无明显差异。
The concentrations in brain and in plasma for compounds B5, D2, D6 demonstrated no significant differences.
血浆蛋白的结合作用会影响药物的分布，并影响药理活性和总血浆药物浓度间的表观关系。
Plasma protein binding influences distribution and the apparent relationship between pharmacologic activity and total plasma drug concentration.
目的：建立加兰他敏血浆药物浓度的HPLC - UV检测法，研究其在人体的药代动力学和相对生物利用度。
OBJECTIVE: to develop a HPLC-UV method to determine the concentration of galanthamine in human plasma and study its pharmacokinetic profiles and bioequivalence.
一些AUC相同而血浆浓度曲线形状不同的药物，具有相同的吸收分量和不同的吸收速率-时间。
Drug products that have similar AUCs but differently shaped plasma-level curves are equivalent in extent but differ in their absorption rate-time profiles.
采用HPLC法测定大鼠肝、肾和血浆中的药物浓度。
The drug concentration in liver, kidney and plasma was determined by HPLC.
达到分布平衡后，便可通过血浆浓度反映组织和细胞外液的药物浓度。
After equilibrium is attained, drug concentrations in tissues and in extracellular fluids are reflected by the plasma concentration.
姜黄素脂质体大鼠口服给药后，以高效液相色谱(hplc)法测定大鼠血浆中的药物浓度。
Drug concentration in rats plasma was detected by high performance lipid chromatography (HPLC) after curcumin liposomes administered to rats.
药物血浆浓度采用HPLC法测定；
高效液相色谱法测定血浆中布比卡因浓度及进行药物缓释作用测定。
HPLC method was used to detect the concentration and releasing effect of bupivacaine in blood serum.
用高效液相色谱法测定不同时间血浆和组织的药物浓度。
The levels of olaquindox in plasma and tissues were determined by HPLC.
采用固相萃取-高效液相色谱法测定大鼠血浆中药物浓度，计算药动学参数和生物利用度。
The blood samples were collected from the rats and the plasma concentration was measured by SPE-HPLC. The pharmacokinetic parameters and absolute bioavailability were evaluated.
结论：CHIP腹腔ddp浓度高，血浆峰值较低，以及高温作用，有利于化疗药物在局部对肿瘤细胞发挥作用，减少肾毒性和全身副作用。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
在高血压患者中，药物血浆浓度与血压-时间曲线相互对应，这表明药物浓度与降压疗效之间密切相关。
In patients with hypertension, the plasma drug concentration and blood pressure versus time curves mirrored each other, indicating a close relationship between concentration and effect.
单靠峰时血浆浓度来确定生物利用度会导致误解，因为药物一进入血流就会开始药物消除。
Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.
当这种弱酸性药物经口服给药时，胃与血浆之间的非解离型药物浓度梯度很大，从而有利于透过胃粘膜扩散。
When the weak acid is given orally, the concentration gradient for un-ionized drug between stomach and plasma tends to be large, favoring diffusion through the gastric mucosa.
在样品分析中，成功分离测定了注射药物的大鼠血浆中的布比卡因，实现了布比卡因血药浓度的快速监测。
When it was applied in sample analysis, bupivacaine was successfully separated and determined from the rat plasma after drug injection, and its concentration monitoring in plasma was carried out.
在样品分析中，成功分离测定了注射药物的大鼠血浆中的布比卡因，实现了布比卡因血药浓度的快速监测。
When it was applied in sample analysis, bupivacaine was successfully separated and determined from the rat plasma after drug injection, and its concentration monitoring in plasma was carried out.
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