换句话说,就像斗牛士的斗篷一样,血凝素的头部将免疫攻击的目标从病毒相对更脆弱的地方转移开。
Like a bullfighter's cape, in other words, the heads of haemagglutinin deflect the immune attack away from more vulnerable parts of the virus.
我们产生的多数抗体是与病毒表面蛋白血凝素的球状头部结合的。
Most of the antibodies we produce bind to the globular heads of a surface protein on the virus called haemagglutinin.
我们只需要提供病毒的血凝素中的保守柄——也就是不变的那部分。
We would only provide the conserved stalk-or the conserved portion-of the virus's hemagglutinin.
血凝素是一种病毒蛋白,能帮助流感病毒侵入宿主细胞。
Hemagglutinin is a viral protein that enables the flu virus to enter host cells.
“血凝素是一个诱饵”,波士顿哈佛医学院的免疫学家韦恩·马拉斯科说,“这些球状头部可以有很多变异还不对病毒产生不好的影响。”
"Haemagglutinin's a decoy," says Wayne Marasco, an immunologist at Harvard Medical School in Boston. "Those globular heads can undergo many mutations without the virus suffering any ill effects."
我们只需要提供病毒的血凝素中的保守柄——也就是不变的那部分。
We would only provide the conserved stalk -or the conserved portion-of the virus's hemagglutinin.
报道还指出,EB治疗是通过与流感病毒血凝素结合,抑制病毒复制,从而阻止了流感病毒与细胞的黏附。
Eb treatment inhibited viral replication by binding to influenza virus hemagglutinin, thereby preventing attachment of influenza virus to cells, the report indicates.
以大肠杆菌表达的传染性法氏囊病病毒(IBDV)衣壳蛋白vp2致敏绵羊红细胞,建立间接血凝试验(IHA)。
An indirect hemagglutination assay (IHA) was set up using sheep erythrocytes sensitized with capsid protein VP2 of infectious bursal disease virus (IBDV) which were expressed in Escherichia coli.
大多数中和抗体识别血凝素,这是主要表面糖蛋白的流感病毒。
Most neutralizing antibodies recognize hemagglutinin , which is the major surface glycoprotein of influenza viruses.
鹅副黏病毒d 1分离株能致死鹅胚、鸭胚和鸡胚,致死率达到100%,感染的尿囊液能产生较高的血凝效价。
The D1 isolate of goose paramyxovirus caused 100% mortality of goose, duck and chicken embryos. Infected allantoic fluid could produce high titer of hemagglutinin test.
由此推断,血凝素可能是病毒衣壳上的一种糖蛋白。
Therefore, it was inferred that the hemagglutinin might be a glycoprotein on the virus capsid.
结果半成品配制前,200批单价病毒液灭活试验全部通过,单价病毒液中较高的血凝素含量会影响灭活试验的判断。
Results All of 200 monovalent pools passed the test for inactivation before preparation of final bulk. The higher content of HA in monovalent pools could affect viral inactivation.
用MDCK细胞进行病毒分离,用血凝抑制试验对分离到的病毒标本进行分型鉴定。
Viral isolation was preformed in MDCK cells and hemagglutination inhibition assay was used for subtype identification.
血凝素(A)蛋白为病毒最重要的表面抗原,具有亚型特异性,同时可以诱导特异性抗体的产生。
Hemagglutinin (ha) is the most important surface antigen of virus and has subtype speciality, which induce the peculiar antibody.
方法:体外抗病毒实验采用鸡胚法,以血凝反应为测定指标。
METHOD: In vitro, the hemagglutination reaction of Feiduqing Granules were tested in the chicken embryo culture.
流感病毒血凝素受体结合位点的氨基酸可以影响受体结合特性。
Aminoacids in the receptor binding sites of hemagglutinin have been shown to be associated with the receptor binding specificity.
病毒对1%的鸡红细胞无凝集作用,并在鸡胚内干扰了B_1系新城疫病毒的血凝素的形成;
The virus could not agglutinate 1% of the chicken erythrocytes and interfered with the development of the hemagglutinins by the B-1 strain of Newcastle disease virus in the chicken embryos.
阐明2006年四川省流行的B型流感病毒血凝素抗原性及其基因变异情况。
To identify the antigenic characteristics and genetic variations of hemagglutinin genes from Influenza B virus, which circulated in Sichuan Province in 2006.
同时还建立了用反向间接血凝抑制(RIHI)试验检测人和动物血清轮状病毒抗体的方法。
Reverse indirect hemagglutination inhibition (RIHI) test was used in the detection of rotavirus serum antibody in cattle.
目的改构高致病性禽流感病毒血凝素基因,建立有效的原核表达体系。
Objective To modify the HA1 gene of high pathogenic avian influenza virus (HPAIV) and to build an efficient prokaryotic expression system of it.
目的构建H5N1亚型禽流感病毒株密码子优化的血凝素(HA)DNA疫苗并研究其免疫原性。
Objective To study the immunogenicity of a DNA vaccine expressing the codon optimized HA gene from an H5N1 avian flu viral isolate, A/Viet Nam1203/04 (H5-VN).
方法通过鸡胚尿囊腔传代自普通级小鼠肺脏分离病毒,经血凝实验、血凝阻断实验和结构基因序列测定对分离得到的病毒进行鉴定;
MethodsThe virus was isolated from conventional mice lungs through chicken embryo passages and identified by haemoglutination test, haemoglutination blocking test and constitution genes sequencing.
研究人员通过该方法设计出来的蛋白,能够结合到广泛流行性病毒1918H1N 1蛋白血凝素(HA)主干上的一个保守的表面区域。
The method was used to design proteins that bind a conserved surface patch on the stem of the influenza hemagglutinin (ha) from the 1918 H1N1 pandemic virus.
研究人员通过该方法设计出来的蛋白,能够结合到广泛流行性病毒1918H1N 1蛋白血凝素(HA)主干上的一个保守的表面区域。
The method was used to design proteins that bind a conserved surface patch on the stem of the influenza hemagglutinin (ha) from the 1918 H1N1 pandemic virus.
应用推荐