现在对这种病已有针对性疗法，Gleevec大体是过去十年中效果最显著的药物，它能使另一融合基因BCR-ABL的编码蛋白失去活性。
There is already a targeted treatment for this disease. Gleevec, probably the most remarkable anti-cancer drug of the past decade, disables the protein encoded by another fused gene, BCR-ABL.
本文论述了基因重组融合蛋白纯化过程和存在的问题。
The paper describes process of recombinant fusion protein in purification and existing problems.
结论GRA7基因在大肠埃希菌中以gst融合蛋白的形式得到表达。
Conclusion The GRA7 gene may be expressed as a GST fusion protein in E. coli.
构建含蛋白转导结构域(PTD)与脑源性神经营养因子(BDNF)融合基因的质粒，并在大肠肝菌中表达。
To construct a recombinant plasmid containing protein transduction domain (PTD) and brain derived neurotrophic factor (BDNF) fusion gene and express in e.
目的构建以融合蛋白形式在大肠杆菌中高效表达心钠素的重组质粒，稳定高效地获得基因工程产品心钠素。
Objective To construct recombinant plasmid with human atrial natriuretic peptide (ANP) gene in fusion form for stable and high level expression of genetic engineering product ANP in E. coli system.
研究目的：克隆表达人肠激酶轻链编码基因，以期应用于融合蛋白的切割与纯化。
Objective: To clone and express the gene of human enterokinase light chain which would be used in the cleavage and purification of fusion proteins.
目的：表达人免疫相关鸟苷三磷酸酶基因(IRGM) a全长融合蛋白，制备高质量的兔抗人IRGM多克隆抗体。
Aim: To express the whole length fusion protein of human IRGMa and prepare high quality rabbit anti-human immune-related gene guanosine triphosphate (IRGM) polyclonal antibody.
结果：成功克隆了CAT的基因片段，并在大肠杆菌中得到其融合蛋白的表达。
Results: The CAT gene was cloned correctly and it's fusion protein was expressed in E.
目的构建克隆载体，分析隐匿性乙型肝炎病毒S基因的突变情况，构建其原核融合蛋白表达载体。
Objective To construct the clone vector of S gene in occult hepatitis B virus infection. To analyse its mutations and to construct its prokaryotic expression vector.
目的：MCPR 1是我室利用消减杂交技术克隆出来的新基因，本研究利用融合蛋白制备mcpr1的多克隆抗体。
Objective: To prepare polyclonal antibodies of MCPR1, which is a novel Mouse Cleft Palate Relate gene cloned by subtractive hybridization method at our department.
结果：将编码人单核细胞趋化蛋白—1（MCP—1）基因克隆至融合表达载体pGEX—2T中，DNA测序证实正确。
Results: A gene fragement encoding MCP-1 was cloned into the fusional expression vector PGEX-2T. DNA sequencing indicated that it was correct.
结果从活化的人白细胞中克隆到IDO基因编码区全长，并构建了IDOEGFP融合蛋白表达载体。
Results The full-length coding sequence of IDO was cloned from activated human leukocytes and the expression vector for IDO-EGFP fusion protein was constructed.
将胰岛素原基因融合到金色葡萄球菌蛋白a的基因上，构建成大肠杆菌中基因融合的外分泌表达载体。
The secretion expression vector of fusion gene in E. coli has constructed by fussing the proinsulin gene to the gene of staphylococcal protein a.
目的：克隆长双歧杆菌ncc 2705株果糖结合蛋白bl 0033的基因，利用大肠杆菌表达GST -BL 0033融合蛋白并纯化。
Objective: to clone the gene of fructose binding protein BL0033 from Bifidobacterium longum NCC2705, and express and purify fusion protein GST-BL0033 in e.
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion proteins.
这项实验发现大鼠的血液干细胞与小鼠的Purkinjie神经元相融合后，停止表达血细胞蛋白，转而表达大鼠神经元特异性基因产物。
This showed nuclei from rat blood stem cells that had fused to Purkinje cells in mice stop expressing blood cell proteins and begin to express rat neuron-specific gene products.
激光共聚焦显微镜观察完整的和去除蛋白激酶A磷酸化位点的线粒体融合素2基因在细胞中的定位。
Laser confocal microscopy was used to observe the locations of Mfn2 gene with and without PKA in cells.
本发明还提供了编码该融合蛋白的基因。
所述接合可以(例如)通过与外壳蛋白的基因融合来实现，或者通过共价、非共价或亲和方式结合来实现。
Conjugation can be, for example, by genetic fusion with the coat protein, or binding via covalent, non-covalent or affinity means.
本发明公开了一种抗乙肝病毒融合蛋白及其编码基因与应用。
The present invention discloses one kind of anti-hepatitis B virus fusion protein and its coding gene and application.
结论：成功克隆葡糖基转移酶CAT基因并获得其融合蛋白的表达，为后续研究奠定了基础。
Conclusion: the target gene and its fusion protein was successfully expressed, which provide a base for the further research.
结论成功克隆人胰腺组织激肽原酶基因，并高效表达融合蛋白，为进一步开发基因工程药物打下基础。
CONCLUSION the fusion protein of the cloned kininogenase gene was highly expressed in E. coli and could be used for the development of its biological products.
目的：利用硫氧还蛋白融合表达系统表达胃癌相关基因gcrg2 13。
Objective: To express gastric cancer related gene GCRG213 using thioredoxin fusion expression system.
研究表明，嵌合基因的不同拼接方式对融合蛋白的活性可能有一定的影响。
It is suggested that the splicing ways of chimeric genes may affect the activities of fused proteins expressed by the chimeric genes.
目的：获得RECK基因GFP融合蛋白表达载体并使其在脑胶质瘤细胞SHG44中表达。
Objective: To obtain GFP-RECK expression vector and to express it in glioma cell line SHG44.
融合蛋白基因在巴斯德毕赤酵母中进行表达后通过阳离子交换层析、反向层析和凝胶过滤对表达产物进行了分离纯化。
HSA-AX15(R13K ) fusion protein was purified to homogeneity by cation exchange chromatography, re verse phase chromatography and gel filtration after expressed in pichia pastor is.
果与电镜和流式细胞光度计的实验结果一致，表明珠蛋白基因产物血红蛋白住杂交细胞中，能够表达并成为融合细胞的标志。
Results indicated that the resultant cybrid cells are characterized by the appearance of hemoglobin and its expression might be served as a marker for the cybrids.
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion prot...
基因工程抗体融合蛋白比传统的化学交联的抗体融合蛋白具有更多的优越性。
Genetically engineered antibody fusion proteins have more advantages over traditional chemical crosslinking antibody fusion prot...
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