这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
此外,组蛋白乙酰转移酶的活性对HIV的增殖是必要的,至少一个科学小组建议组蛋白乙酰转移酶或相似的酶做为靶点也许是抑制病毒一个新方式。
In addition, hat activity is necessary for the multiplication of HIV, leading at least one scientific group to suggest that targeting HATs or similar enzymes might be an new way to thwart the virus.
结果:桑黄能提高肝损伤大鼠的蛋白质合成能力,显著降低血清氨基酸转移酶水平和胶原成分含量。
Results: Synthesis of protein was improved and the serum levels of aminotransferases and collagen were significantly decreased in prophylactic group.
目的探讨脑血栓病人卵磷脂胆固醇酰基转移酶(LCAT)活性与脂蛋白成分的相关性。
Objective To explore the relation between the activity of lecithin-cholesterol acyltransferase(LCAT) and the composition of lipoprotein in cerebral thrombosis patients.
目的为建立能稳定表达人葡糖醛酸转移酶UDPGT1A9蛋白的CHL UDPGT1A9转基因细胞系,并鉴定其对药物的葡糖醛酸缀合活性。
AIM To establish a cell line CHL UDP glucuronosyltransferase gene (UDPGT1A9) which will stably express human UDPGT1A9 protein and determine the activity of expressed UDPGT1A9 in drug glucuronidation.
不同蛋白质修饰剂对环糊精葡萄糖基转移酶进行修饰。
The effects of some protein modification reagents on the activity of cyclodextrin glucanotransferase (CGTase) have been studied.
DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
组蛋白乙酰转移酶和组蛋白去乙酰酶活性共同决定了组蛋白的乙酰化水平。
The level of his-tone acetylation is determined by the activities of histone acetyltransferases and histone deacetylases.
组蛋白乙酰化与基因转录等生物效应有密切的关系,组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。
Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.
本文主要就组蛋白乙酰转移酶调节基因转录以及组蛋白去乙酰化酶抑制剂促进记忆形成的作用机理进行综述。
In this paper, we reviewed the mechanisms on histone acetyltransferases regulating gene transcription and histone deacetylase inhibitors promoting memory formation.
结论:成功克隆葡糖基转移酶CAT基因并获得其融合蛋白的表达,为后续研究奠定了基础。
Conclusion: the target gene and its fusion protein was successfully expressed, which provide a base for the further research.
其中之一就是S-亚硝基化,我们已经和霍普金斯的一个研究组合作了一些研究,结果一种蛋白,谷氨酰胺转移酶2,似乎能被这一S-亚硝基化过程所影响。
One area is S-nitrosylation, where we've been doing some work with a group at Johns Hopkins, the protein, transglutaminase2, seems to be effected by this process S-nitrosylation.
本研究是对推测的小麦组蛋白乙酰转移酶及脱乙酰化酶基因功能研究的首次报道。
This is a first report about function study of histone acetyltransferase and deacetylase in wheat.
本发明涉及某些法呢基:蛋白质转移酶的抑制剂,它作为抗肿瘤剂是有用的。
The present invention relates to certain inhibitors of farnesyl: protein transferase which are useful as antineoplastic agents.
此外,肌动蛋白还能与染色质改构复合物和乙酰转移酶复合物相互作用,在染色质结构的调整方面也发挥重要作用。
Furthermore, nuclear actin has been found to be associated with chromatin remodeling and histone acetyltransferase complexes, suggesting a role for actin in chromatin remodeling.
方法采用美国标准化委员会的标准化文件EP10 T2 ,选择具有代表性的丙氨酸氨基转移酶(ALT)、血清总蛋白(TP) ,采用酶法测定ALT ,双缩脲法测定TP。
Method U. S Standardization Com mission's standard file EP10-T2 was used to select representative ALT and TP. AL T was determined with the enzyme reaction, TP was determined with biuret reaction .
三种不同类型的DGAT蛋白序列相似性比较低,但是均含有一个酰基转移酶保守结构域,而同一类型的DGAT蛋白C端高度保守。
The DGAT proteins of three different types share lower similarity, but all of them have an acyltransferase domain, while the DGAT proteins of the same type appear to be conserved in the C-terminal.
目的鉴定日本血吸虫中存在的腺嘌呤磷酸核糖转移酶,分析其蛋白结构特征。
Objective To identify adenine phosphoribosyltransferases in Schistosoma japonicum and analyze their structural features.
的突变在诊断或复发时获得的,和导致截断保守的氨基酸残基的组蛋白乙酰转移酶结构域的基因或有害的替代。
The mutations were either present at diagnosis or acquired at relapse, and resulted in truncated alleles or deleterious substitutions in conserved residues of the histone acetyltransferase domain.
专一性检测H3-K9组蛋白甲基转移酶活性/抑制性。
Specific measurement of activity/inhibition of H3-K9 histone methyltransferases.
专一性检测H3-K9组蛋白甲基转移酶活性/抑制性。
Specific measurement of activity/inhibition of H3-K9 histone methyltransferases.
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