2，5和2，6双取代氮茚类似物被用作蛋白激酶抑制剂。
2,5- and 2,6-disubstituted benzazole analogues are used as protein kinase inhibitors.
环腺苷酸结合蛋白激酶的调节亚基：一个磷酸化蛋白激酶磷酸化酶激酶。
Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
比如说，如果你真正着迷于蛋白激酶生物化学，你不一定要在肿瘤学范围内研究激酶。
If one is really, for instance, captivated by the biochemistry of protein kinases, you don't necessarily have to work on kinases in oncogenesis.
在许多炎症性疾病，如感染性休克(9)，与银屑病(10)，酪氨酸蛋白激酶的活动会表现出变化。
In many inflammatory diseases such as septic shock (9), and psoriasis (10) the change in protein tyrosine kinase activity has been shown.
病毒癌基因最常为逆转录病毒致癌基因的产物。通常具有转化和蛋白激酶活性。
Products of viral oncogenes, most commonly retroviral oncogenes. They usually have transforming and often protein kinase activities.
在小鼠模型中，GNA11突变诱导了自发转移性肿瘤，激活了丝裂原活化蛋白激酶途径。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
公司主要关注核苷酸化学，尤其侧重环状核苷酸为基础的各种蛋白激酶、磷酸二酯酶和离子通道等的抑扬调节剂。
The company has its focus on nucleotide chemistry with special emphasis on cyclic nucleotide-based modulators of respective protein kinases, phosphodiesterases and ion channels, etc.
对有肺癌的实验鼠进行实验，研究发现依赖性蛋白激酶1 (Cdk1)让DNA停止修复。
In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.
它结合并激活蛋白激酶c，对很多细胞和组织产生影响(1,2)。
It binds and activates protein kinase c, causing a wide range of effects in cells and tissues (1, 2).
结论：有氧运动能改善胰岛素抵抗，肝细胞中蛋白激酶B表达水平与胰岛素抵抗可能有关。
CONCLUSION: Aerobic exercise can improve the insulin resistance, the level of PKB expression in liver cells may be related with insulin resistance.
蛋白激酶是数量最多的一类激酶，作用和修饰特定蛋白的活性。
The largest group of kinases are protein kinases, which act on and modify the activity of specific proteins.
受体酪氨酸蛋白激酶是细胞信号转导进行的关键信号酶，在生长因子调控细胞生长、发育与功能的过程中起着重要的生理作用。
Receptor tyrosine protein kinase is one of key kinases in cell signal transduction and plays an important role in the process of cell growth, development and functions regulated by growth factors.
目的：寻找猪血小板中蛋白激酶CK2可能的天然底物。
Objective:To search for natural substrates of protein kinase CK2 in pig platelets.
目的：观察体外藤黄菌素对重组人蛋白激酶CK2的抑制效果及进行酶动力学分析以确定其抑制作用类型。
AIM: to observe the inhibitory effect of luteolin on recombinant human protein kinase CK2 holoenzyme and to confirm the inhibitory type by its enzyme kinetic analysis in vitro.
目的：研究提高细胞培养温度对仔猪肝细胞一磷酸腺苷激活蛋白激酶(AMPK)活性及脂质代谢产物的影响。
Objective: to study the influence of high cell incubating temperature on AMP-activated protein kinase (AMPK) activity and lipid metabolites of piglets hepatocytes in vitro.
就近十年来国内外学者对植物蛋白激酶的发现，家族分类，磷酸化过程及其生理功能等方面的研究进行综述。
It is systematically reviewed that the discovery of the plant protein kinase, including the research survey, family classification, the process of phosphorylation and the circadian function.
目的检测乳腺癌中死亡相关蛋白激酶(DAPK)表达，探讨其与细胞凋亡的关系及其在乳腺癌中的作用。
Objective: to investigate the expression of death associated protein kinase (DAPK) and the relationship between DAPK and cell apoptosis in breast carcinoma.
心舒康可降低压力负荷增加大鼠心肌组织蛋白激酶的高表达，从而逆转其左心室肥厚。
Xinshukang may decrease the high expression of myocardium protein kinase in rats with increasing pressure load and reverse the left ventricular hypertrophy.
蛋白激酶在植物生长、激素调节和生物与非生物逆境胁迫反应中起着重要的作用。
Protein kinases play important roles in plant growth and development, hormone response as well as in response to abiotic and biotic stress.
目的：探讨心肌缺氧时AMP激活的蛋白激酶（AMPK）激活对葡萄糖转运子4（GL UT4）移位和葡萄糖摄取的作用。
Objective: To investigate the effects of AMP activated protein kinase (AMPK) activation on translocation of glucose transporter 4(GLUT4) and glucose uptake in hypoxic rat myocardium.
近来的研究显示，某些类型遗传损伤是很多肿瘤细胞的共同原因，导致蛋白激酶从细胞内部运动到细胞膜的表面。
Recent research has shown that certain types of genetic damage, common to many cancer cells, lead to the movement of PKB from the interior of the cell to its surface membrane.
目的观察阻断肾素血管紧张素系统对糖尿病大鼠肾组织蛋白激酶C（PKC）活性的影响。
Objective To investigate the effects of blocking renin-angiotensin system on protein kinase C (PKC) activity in diabetic rat kidney.
目的：研究细胞外信号调节蛋白激酶（ERK）信号通路在癫痫大鼠脑内的表达规律及其意义。
Objective: To investigate the expression of extracellular signal regulated protein kinase(ERK) signal transduction pathway and its significance in the rat brain after epileptic seizures.
因此人们尝试着取得一些基因水平的测试蛋白激酶突变表达的方法。
So people will try and get some sort of gene-based test to measure the expression-mutation of these kinases.
目的：探讨丝裂原活化蛋白激酶在非小细胞肺癌中的表达及其临床意义。
To investigate the expression and activation of mitogen-activated protein kinases in non-small cell lung cancer and its clinical significance.
目的探讨丝裂素活化蛋白激酶（MAPK）在动脉球囊损伤后内膜增殖过程中表达的变化。
Objective To observe the changes in mitogen-activated protein kinase (MAPK)activity and gene expression after coronary artery balloon injury in rabbits.
目的观察木犀草素对HL- 60细胞内蛋白激酶C活性的影响。
Objective To observed the influence of luteolin on protein kinase C activity in human leukemic cells (HL-60).
目的探讨丝裂素活化蛋白激酶(MAPK)在肾性高血压致心肌肥大中的作用。
Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.
目的探讨丝裂素活化蛋白激酶(MAPK)在肾性高血压致心肌肥大中的作用。
Objective to investigate the effect of mitogen-activated protein kinase (MAPK) on pathogenesis in myocardium hypertrophy of renal hypertension rats.
应用推荐