结论渗透促进剂可以不同程度地影响膜脂流动性和膜蛋白构象，提高胰岛素经舌下给药后的降糖效果。
CONCLUSION Penetration enhancers can change the fluidity of membrane lipid and the conformation of membrane protein in certain degrees, and increase the sublingual absorption of insulin.
当配体与特定的受体结合，他能稳定蛋白构象，通过打开(或关闭)分子开关控制细胞内不同的分子功能。
When ligands bind to a specific subset of receptors, the ligands stabilize specific protein conformations, turning on (or off) molecular switches that control diverse cellular functions.
一旦串联完成，蛋白质会自动形成正确的构象并发挥作用。
Once the string is complete, the protein snaps itself into the right shape and gets to work.
此外，在内质网中，钙网蛋白以非天然构象保存，并对其进行靶向降解(2,3)。
Furthermore, calreticulin retains proteins in non-native conformation within the er and targets them for degradation (2, 3).
萤光光谱法是研究蛋白质在水溶液中分子构象的一种有效方法。
Fluorescence spectroscopy is an effective method of study on protein conformation in aqueous solution.
本文在构造具有方向导向性的完全二叉树的基础上，提出了一种适合研究蛋白质构象的格子模型快速穷举搜索算法。
This paper presents a fast exhaustive search algorithm in order to search the protein conformation space based on the lattice model by constructing a directional binary tree.
首先，简要地介绍了遗传算法和一般的蛋白质构象搜索问题。
A general protein conformation searching and genetic algorithms are briefly introduced first.
目的确定葡萄球菌蛋白a胶体金分子特征性构象。
Objective To determine the characteristic conformation of Staphylococal protein A-gold.
蛋白质结构构象呈现明显的规律，研究其在特定构象空间的分布对蛋白质结构预测和模拟具有重要意义。
Research on conformational space of protein structure in which proteins take clear regulation plays a key role in protein structure prediction and simulation.
一般还认为乙二醇有稳定蛋白结构的作用，构象不稳定的蛋白可以尝试添加乙二醇来长晶体。
It is even thought that ethylene glycol can have a structure-stabilizing effect and may be useful in the crystallization of flexible proteins.
这一形式表明蛋白质变性是一个构象渐变的过程。
It indicates that protein denaturation is a sequential process for the conformational changes.
蛋白质的改性指的是用物理、化学或酶法改变蛋白质的构象和结构，从而改变其理化性质。
Modification of a protein usually refers to physical, chemical, or enzymatic treatments changing its conformation and structure and consequently its physicochemical and functional properties.
最近研究表明，信使RNA在蛋白质合成中，不但表现出一维序列上的对应，且在两者的空间构象上也表现出某些对应关系。
Recently, it has been proved that an mRNA molecule instructs the corresponding protein synthesizing not only in the primary structure but also in the conformation.
连接蛋白的表达和构象的改变影响裂隙连接的通透性，从而改变细胞间通讯。
Expression and aerial image of connexins in lens cells will affect gap junctional permeability and alter intercellular communication.
由于其独特的结构和性能，近年来在蛋白质结构模拟、分子链构象研究、生物医学等领域被广泛地加以研究。
Due to their unique structures and properties, synthetic polypeptides recently have been studied widely in the field of protein simulation, macromolecular conformational study and biomedicine.
有关研究也发现，声场作用会引起蛋白酶分子构象发生一定程度的变化。
Also the conformation of protease molecule was effected to some extent by sound field.
品状体结构蛋白的非酶糖基化引起晶状体构象变化在糖尿病性白内障的发生中起重要作用。
It is vital in the diabetic cataract formation that the non-enzymic glycosylation of the lens structural proteins by glucosamine induces conformational changes in the lens.
红外光谱和拉曼光谱是研究蛋白质构象的有力手段，因此在丝蛋白结构的研究中也有广泛的应用。
Both infrared and Raman spectroscopy are the powerful tools for the investigation of the protein conformations, so they are widely used in the study of silk proteins as well.
本文综述了声场对蛋白酶催化活力及分子构象的影响。
The effect of sound field on the catalysis activity and the molecular conformation of protease was discussed.
这些聚集态决定了引起各藻胆蛋白之间光谱特性差别的藻蓝胆素发色团的构象。
The assembling states lead to the different conformations of phycocyanobilins chromophores in C-phycocyanin and allophycocyanin which cause different spectral properties.
现已公认晶状体的透明性是由其蛋白质的天然构象来维持的。
Preservation of this organization is maintained by the fidelity of native proteins.
因此，蛋白质在吸附过程中，构象会发生变化，甚至导致失活。
Therefore the conformation of protein can change and even the protein can be inactivated in the process of adsorption.
以碱金属离子诱导桑蚕丝素蛋白溶液发生构象转变，研究了蛋白质初始结构对其矿化作用的影响。
In this study, we studied the effect of initial Bombyx mori silk fibroin structure on the protein biomineralization, where the structural transition was induced by the alkali metal ion treatment.
二十面体病毒衣壳结构蛋白具有不同的构象。
It was indicated that structural protein of icosahedral viruses capsid in fact take on various conformations.
该蛋白的二级结构包含螺旋构象10%、折叠构象17%、转角构象21%及无规则卷曲53%。
The second structure of LGBP has 10 % helix, 17 % sheet, 21 % turn and 53 % coil.
该蛋白的二级结构包含螺旋构象10%、折叠构象17%、转角构象21%及无规则卷曲53%。
The second structure of LGBP has 10 % helix, 17 % sheet, 21 % turn and 53 % coil.
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