目前已有80多个国家批准了复方蒿甲醚的注册。
目的观察蒿甲醚伍用伯氨喹治疗恶性疟的疗效和副作用。
Objective To evaluate the efficacy and side effects of artemether combined with primaquine in the treatment of falciparum malaria.
口服蒿甲醚对肝、肾功能、网织红细胞和心电图未见明显异常。
No apparent changes in hepatic and renal functions, reticulocyte count or electrocardiograph was evidenced after completion of artemether administrartion.
他们用青蒿素的一种衍生物——蒿甲醚代替青蒿素,协助改进了固定复方药。
They helped improve the fixed combination by replacing artemisinin with [one of its derivatives], artemether.
但是三种抗疟药——青蒿素、青蒿琥酯和蒿甲醚——栓剂的有效性从未进行过比较。
But the three types of antimalarial available in suppository form - artemisinin, artesunate and artemether - have never been compared for effectiveness.
结论:蒿甲醚具有诱导胃腺癌s GC- 7901细胞凋亡的作用。
Conclusion: ART possess induce SGC-7901cells apoptosis in vitro.
方法涂布法制备蒿甲醚贴剂,考察不同促进剂、药物的浓度对透皮速率的影响;
METHODS The patch was prepared through spreading method and the influence of different factors(enhancers and concentration)was investigated.
结果表明,实验值与计算值吻合良好,且蒿甲醚亚稳区宽度随不同的操作条件,发生相应的变化。
It is found that the experimental data of MSZW show good agreement with the calculated values, and the width of MSZW have different changes under different operating conditions.
结论:口服蒿甲醚,对山区感染较重的血吸虫病流行区有较好的预防效果,并可防止急性血吸虫病。
CONCLUSION: in schistosomiasis endemic area of mountainous type, oral Art exhibited a promising preventive effect on both reducing infection rate and controlling acute schistosomiasis.
方法采用双盲随机对比法,共收治恶性疟患者151例,其中蒿甲醚为50例,本芴醇为51例,复方蒿甲醚为50例。
Methods Of 151 patients, 50 patients were treated with artemether , 51 patients were treated with benflumetol and 50 patients were treated with combined regime(co-artemether).
青蒿素类药物是治疗疟疾的主要药物,其衍生物有青蒿琥酯、蒿甲醚和二氢青蒿素等,主要的作用机制是通过铁离子介导的细胞损伤。
Artemisinins are the major drugs of antimalarial. Its derivatives include artesunate, artemether, dihydroartemisinin and etc. Artemisinins exert their antimalarial activity by iron-mediated cleavage.
青蒿素类药物是治疗疟疾的主要药物,其衍生物有青蒿琥酯、蒿甲醚和二氢青蒿素等,主要的作用机制是通过铁离子介导的细胞损伤。
Artemisinins are the major drugs of antimalarial. Its derivatives include artesunate, artemether, dihydroartemisinin and etc. Artemisinins exert their antimalarial activity by iron-mediated cleavage.
应用推荐