目的：研究原代分离的大鼠胰岛对葡萄糖刺激的胰岛素分泌反应性。
Objective To study the insulin secretion responsiveness induced by glucose stimulation in isolated rat islets.
通常是很简单的-通常是简单的使GLP - 1增多，葡萄糖刺激的胰岛素分泌就增加。
It used to be very simple - it used to be that you simply increased the amount of GLP-1 which makes you secrete more insulin in response to glucose.
离体胰岛胰岛素的分泌依赖于孵育液中的葡萄糖浓度，CDS明显刺激胰岛素的释放。
Insulin secretion of the isolated islets was dependent on the glucose concentration of incubation medium. CDS could stimulate insulin secretion significantly.
离体胰岛胰岛素的分泌依赖于孵育液中的葡萄糖浓度，CDS明显刺激胰岛素的释放。
Insulin secretion of the isolated islets in incubation medium was glucose concentration-dependent positively. The CDS could stimulate insulin secretion of the islets significantly.
研究显示，高蛋白饮食可增进正常个体胰岛素分泌，导致骨骼肌胰岛素抵抗，刺激内源性葡萄糖的产生。
Researches have shown that high-protein diet can enhance insulin secretion, induce insulin resistance in skeletal muscle, and stimulate endogenous glucose production.
这就意味着这些患儿的胰岛素分泌由于葡萄糖刺激而受损，这也是新生儿糖尿病病情进展的原因。
That means that there is impaired insulin secretion in this person with glucose, and that is why they develop diabetes in the neonate.
通过葡萄糖刺激胰岛素释放实验，对胰岛分泌功能的检测，得出结果，实验组与对照组胰岛分泌功能无明显差异。
According to glucose stimulating test, there was no significant difference on in vitro insulin secreting function of NICC between the experiment and control group.
结果：（1）随着刺激的葡萄糖、H2O2浓度升高，INS-1细胞内ROS浓度和分泌的胰岛素逐渐升高。
Results: Concentrations of ROS in INS-1 cells and secreted insulin increased along with increased glucose or H2O2 exposure.
结论：ROS、PTEN及P -AKT参与了葡萄糖刺激INS - 1细胞分泌胰岛素的信号通路，成为介导胰岛素分泌的信号分子。
Conclusion: ROS, PTEN and p-AKT are involved in the signaling pathway of glucose-stimulated insulin secretion in INS-1cell, as signaling molecules in insulin secretion.
结论：ROS、PTEN及P -AKT参与了葡萄糖刺激INS - 1细胞分泌胰岛素的信号通路，成为介导胰岛素分泌的信号分子。
Conclusion: ROS, PTEN and p-AKT are involved in the signaling pathway of glucose-stimulated insulin secretion in INS-1cell, as signaling molecules in insulin secretion.
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