志贺菌在与宿主肠道上皮细胞接触后，激活t3ss并将效应子蛋白注入真核宿主细胞内，引起细菌性痢疾。
Once Shigella makes contact with intestine epithelium, the T3SS is activated and effector proteins are injected into the cytosol of intestine epithelium to cause shigellosis.
细菌性痢疾，又称为志贺氏菌病，由志贺氏菌属细菌引起，轻症者症状轻微，重者突然发病，症状严重，可致命。
Bacillary dysentery (shigellosis) caused by shigella bacteria may be mild or may be sudden severe and fatal.
志贺菌属的细菌以人类为特异性宿主，感染人类肠上皮细胞，多导致痉挛性腹痛、腹泻、发烧等症状，是细菌性痢疾最为常见的病原菌。
Shigella spp. is human host-specific pathogens that infects intestinal epithelial cells. It is the causative agent of dysentery which is followed by cramps, diarrhea and fever.
志贺菌属的细菌以人类为特异性宿主，感染人类肠上皮细胞，多导致痉挛性腹痛、腹泻、发烧等症状，是细菌性痢疾最为常见的病原菌。
Shigella spp. is human host-specific pathogens that infects intestinal epithelial cells. It is the causative agent of dysentery which is followed by cramps, diarrhea and fever.
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