结论：DZ选择性地抑制了AP在人体肝脏中的4羟基化代谢途径，提示DZ是一作用较强的、选择性的肝药酶抑制剂。
CONCLUSION:DZ inhibited the 4 hydroxytative metabolic pathway of AP, suggesting DZ may be a potent and selective microsomal enzyme inhibitor.
这种药物主要是通过抑制切割酶来起作用的，并且在2007年夏天该药已开始临床试验了。
That drug, which works by inhibiting the cutting enzyme, began human clinical trials in the summer of 2007.
依赖于半胱氨酸蛋白酶的激活，美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
噻嗪类药激活由钙激活的血管平滑肌钾通道，抑制血管组织中的各种碳酸酐酶。
Thiazides cause vasodilation by activating calcium-activated potassium channels in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
大鼠模型的研究发现BH4合成酶在损伤的神经元中被激活，而那些抑制这些酶活性的物质象镇痛药一样能够减少疼痛。
Tests in rat models found that the BH4-synthesizing enzymes were activated in injured sensory neurons and that substances known to inhibit those enzymes reduced pain, acting as analgesics.
通过本文的研究为以后开发糖苷酶抑制剂药及生物农药提供了一定的理论基础。
All of studies in this dissertation offer references to research and development of glycosidase inhibitor medicine and bio-pesticide.
我们比较了血管紧张素转换酶抑制剂雷米普利、血管紧张素受体拮抗剂替米沙坦以及两药联合对有血管性疾病或高位糖尿病患者的作用。
We compared the ACE inhibitor ramipril, the ARB telmisartan, and the combination of the two drugs in patients with vascular disease or high-risk diabetes.
血管紧张素转化酶抑制剂和血管紧张素受体拮抗剂联合用药治疗CKD是否比单药应用要好？
Is Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Combination therapy Better Than Monotherapy and Safe in Patients With CKD?
目的介绍选择性环氧化酶（COX）-2抑制剂与抗炎植物药研究概况。
Objective To review the research progress of selective cyclooxygenase-2 (COX-2) inhibitors and anti-inflammatory herbs.
还对分化诱导剂、拓扑异构酶抑制剂、抗微管药和生物反应调节剂的筛选方法进行了评述。
In addition, the paper reviewed screening methods for differentiation inducers, DNA topoisomerase inhibitors, antimicrotubule drugs and biological response modifiers.
蛋白酶体抑制剂可选择性地促进肿瘤细胞凋亡，逆转多药耐药。
Proteasome inhibitors can selectively promote the apoptosis of tumor cells and overcome MDR.
其研究结果将为合理设计新型顶体酶抑制剂，寻找男性口服避孕药奠定坚实基础。
These results provided a basis for the rational design of specific inhibitors to the target enzyme and the discovery of novel contraceptive agents with high potency.
抗肿瘤药罗米地辛是一种有效的组蛋白去乙酰化酶抑制剂，临床 上用于治疗皮肤T细胞淋巴瘤。
Romidepsin is a potent histone deacetylase inhibitor, and is used in the treatment of cutaneous T-cell lymphoma (CTCL).
该药与芳香化酶抑制剂联合使用治疗HER2和激素受体共同阳性乳腺癌的绝经后女性。
It is also approved for use in combination with an aromatase inhibitor for the treatment of postmenopausal patients with HER2 and hormone receptor co-positive metastatic breast cancer.
目的介绍抗高血压药血管紧张素转化酶抑制剂（ACEI）依那普利的研发及市场情况。
Objective To introduce the research and market development of enalapril as an angiotensin 1-converting enzyme inhibitor (ACEI) for treating hypertension.
酶抑制引言几乎所有的治疗药物是酶抑制剂，从老药，如阿司匹林与青霉素用于治疗艾滋病毒感染的最新化合物框标准。
Enzyme Inhibition INTRODUCTION Almost all therapeutic drugs are enzyme inhibitors, from old medicine box standards such as aspirin and penicillin to the newest compounds used to treat HIV infection.
有一部分药可以用于治疗特定的病毒，如蛋白抑制酶可以用来控制艾滋病感染，但这些数量相对较少，并且病毒易产生耐药性。
There are a handful of drugs that combat specific viruses, such as the protease inhibitors used to control HIV infection, but these are relatively few in number and susceptible to viral resistance.
环氧化酶-2抑制剂和大多数的非甾体类消炎药（NSAIDs）的抗心血管疾病的效果并没有肯定，还需进一步研究。
The effect of cyclooxygenase-2 inhibitors and most nonsteroidal anti-inflammatory drugs (NSAIDs) on cardiovascular risk is not completely determined and should be studied further.
结果说明杀虫剂与酯酶的药代动力学互作对混剂的酯酶的抑制作用方式和活性具有重要影响。
These results suggested that the toxicokinetic interactions between the insecticides and the easterases play an important role in the joint action of the insecticide-combinations on the enzyme.
本发明还提供了胆碱酯酶抑制剂在制备用于治疗口腔干燥症的对口腔粘膜局部给药的药物方面的用途。
The invention also provides a use of cholinesterase inhibitor in the treatment of xerostomia for topical delivery to the oral mucosa.
结果钙拮抗剂、肾上腺素受体阻滞药、血管紧张素转化酶抑制剂(acei)在用药金额、用药频度上分别占前三位。
Results the amount used DDDs of calcium antagonists, adrenergic receptor blockers and ACEI drugs were the head of three.
结果钙拮抗剂、肾上腺素受体阻滞药、血管紧张素转化酶抑制剂(acei)在用药金额、用药频度上分别占前三位。
Results the amount used DDDs of calcium antagonists, adrenergic receptor blockers and ACEI drugs were the head of three.
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