方法:采用干酵母致大鼠发热、蓖麻油致小鼠腹泻、醋酸致小鼠扭体及体外抑菌等药理模型。
Methods: The pharmacological models of pyrexia induced by yeast in rats, diarrhea induced by castor oil in mice, writhes induced by acetic acid in mice and bacteriostatic test in vitro were applied.
方法:采用温浴甩尾法和扭体法镇痛试验、毛细血管通透性试验、组胺致瘙痒等药理模型。
Methods: analgesic test with water bath, writhes induced by acetic acid, tickling induced by histamine and capillary permeability increase tests were applied.
对近年现代药理学研究左金丸治疗消化系统疾病的机制、药理模型、药效成分等进展进行了概述。
This paper summarizes the modern pharmacological progress on formula of Zuojin Pills from several aspects of mechanism of digestive system disease, model of pharmacology, effective component, etc.
以临床药理模型为基础的新药研发及评估, 孙鹤博士,旅美中国药学家学会,美国食品和药物管理局专家审批官。
Pharmacometrics Model Based New Drug Development and Evaluation, He Sun, Ph. D. , Food and Drug Administration, Association of Chinese-American Pharmaceutical Scientists, MD, USA.
方法:采用相应的药理学模型研究当玛- 5胶囊在镇痛、止泻、小肠吸收、胃蛋白酶活力、抗溃疡等方面的作用。
Methods: Appropriated animal models were used to observe the effect of Dangma 5 Capsule on analgesic, anti diarrhea, intestinal absorption, pepsin activity and anti ulceration.
局部的讨论根除是生物体hiv潜伏感染后的模型,具有多种药理作用的研究方法延迟刺激原病毒基因的表达。
Topical to the discussion of HIV eradication is the biology behind latent infection as well as models for the study of latency and pharmacological approaches to stimulate proviral gene expression.
在这两种模型中通过基因消融血管内皮生长因子- A也发现侵袭性增加,证实药理抑制剂的结果。
Increased invasiveness is also seen by genetic ablation of the Vegf-A gene in both models, substantiating the results of the pharmacological inhibitors.
采用肾上腺素诱发清醒家兔心律失常和结扎冠状动脉造成麻醉大鼠心律失常模型进行药理试验。
Its antiarrhythmic effect is evaluated in conscious rabbit and anesthetized rat models of arrhythmia induced by epinephrine and coronary ligation.
应用动物模型研究了纯化毒素的药理活性。
The pharmaceutical activities of the purified toxins were studied with animal models.
前期的药理试验证明,其水提物对大鼠实验性肝缺血再灌注损伤模型(IR)有明显的保肝作用,而且进一步的研究表明主要起作用的成分为核苷类。
The primary experiment has revealed that its aqueous extract has obvious effects of liver protection based on IR model, and that the main functional components are nucleosides.
对山茱芡环烯醚菇总普和总三菇酸部分,用大鼠、小鼠糖尿病模型进行了降糖作用的药理实验,结果表明,二部分单用均有降糖作用,但合用效果更明显。
The pharmacological results revealed that both the active parts of iridoids and triterpenes acid had effects on decreasing blood glucose, though the joint use showed the better results.
方法口服给药,采用乙醇致小鼠胃粘膜损伤模型、冰醋酸致大鼠胃溃疡模型、醋酸致小鼠疼痛模型、二甲苯致小鼠耳肿胀模型等考察受试物的药理学作用。
Methods To investigate the pharmacological effect of IYC in rats and mice by oral administration, peptic ulcer and gastric mucosal damage model, ear swelling one, stomache one, and so on were adopted.
利用行为敏化模型,率先开展了曲马朵和槟榔嚼块提取物多药滥用的精神药理学研究。
Using behavioral sensitization animal models, poly-drug abuse about tramadol and betel quid extract was investigated in psychopharmacological profiles.
方法:采用应激性溃疡和慢性乙酸溃疡大鼠模型,观察舒胃散治疗慢性胃炎、胃溃疡的药理作用;
Methods:Taking some stress ulcer and chronic acetic ulcer rats as a model, observing Shuweisan s pharmacological action on treating chronic gastritis and stomach ulcer;
结论KM小鼠感染仙台病毒可作为副流感病毒感染的疾病模型,应用于药理学等生物医学研究中。
Conclusion SV_infected KM mice can be used in model of anti_parainfluenza virus infected disease and pharmacology researches.
昆明鼠物体识别模型具有简单、快速、可靠等特点,可以在安全药理学研究中用来检测化学药物对记忆的损伤。
The object recognition task in KM mice, which is simple, rapid, and reliable, should be of great use in safety pharmacology to detect amnesic properties of new compounds.
目的在中医药理论指导下建立SD大鼠阳虚便秘动物模型并对其进行评价。
Aim To establish and evaluate Sprague-Dawley (SD) rats model with yang-deficiency and constipation at the direction of traditional Chinese medicine theories.
体外培养的脐静脉内皮细胞做为研究血管的模型对研究药理学和血管疾病起着重要作用并将进一步提供信息。
In vitro culture of human VSMC as a model of vascular research has played a critical role and continue to provide information in the pharmacology and therapy of vascular diseases.
人血管平滑肌的体外培养可作为血管研究模型,为血管疾病的治疗和药理学研究提供信息,发挥重要作用。
In vitro culture of human vascular SMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.
目的体外构建黑素瘤细胞与角质形成细胞直接接触的混合培养模型,观察白消一号方对此模型中黑素瘤细胞的影响,探讨其治疗白癜风的药理作用。
Objective to construct the mixed cultivating model of keratinocytes and melanoma cells, and to observe the effect of Baixiao Yihao decoction on melanoma cells.
方法:本实验采用环磷酰胺所致白细胞减少的小白鼠动物模型,研究海洋生物多糖FW-1对模型小鼠外周血白细胞数,骨髓有核细胞数,免疫器官重量等指标的药理作用。
Results FW-1 could obviously increase the quantity of peripheral leukocytes of mice induced by CTX, so do the quantity of bone marrow cells and the weight of splenic organ and thymus.
目的观察三勒浆抗疲劳液对慢性疲劳大鼠模型的多因素影响作用,为深入探讨其药理学作用的机制奠定基础。
Objective to observe the effect of chronic fatigue rat model which influenced by Sanajon oral liquid, to study the pharmacology mechanism.
方法:制造大鼠佐剂性关节炎模型、小鼠迟发性超敏反应(DTH)模型和醋酸扭体疼痛模型,观察复方黑蚂蚁胶囊的药理作用。
Methods: the adjuvant arthritis model of rats (AA rats), delayed hypersensitivity (DTH) model and the pain model induced by acetic acid in mice were used.
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
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