• 方法:采用干酵母大鼠发热、蓖麻小鼠腹泻醋酸致小鼠扭体体外菌等药理模型

    Methods: The pharmacological models of pyrexia induced by yeast in rats, diarrhea induced by castor oil in mice, writhes induced by acetic acid in mice and bacteriostatic test in vitro were applied.

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  • 方法:采用温甩尾法扭体法镇痛试验毛细血管通透试验组胺致瘙痒等药理模型

    Methods: analgesic test with water bath, writhes induced by acetic acid, tickling induced by histamine and capillary permeability increase tests were applied.

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  • 对近年现代药理研究左金治疗消化系统疾病机制药理模型、药效成分进展进行了概述

    This paper summarizes the modern pharmacological progress on formula of Zuojin Pills from several aspects of mechanism of digestive system disease, model of pharmacology, effective component, etc.

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  • 以临床药理模型为基础新药研发评估, 孙鹤博士,旅美中国药学学会美国食品药物管理局专家审批官。

    Pharmacometrics Model Based New Drug Development and Evaluation, He Sun, Ph. D. , Food and Drug Administration, Association of Chinese-American Pharmaceutical Scientists, MD, USA.

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  • 方法采用相应药理模型研究- 5胶囊镇痛、止小肠吸收胃蛋白酶活力溃疡等方面的作用。

    Methods: Appropriated animal models were used to observe the effect of Dangma 5 Capsule on analgesic, anti diarrhea, intestinal absorption, pepsin activity and anti ulceration.

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  • 局部讨论根除生物体hiv潜伏感染模型,具有多种药理作用研究方法延迟刺激原病毒基因表达

    Topical to the discussion of HIV eradication is the biology behind latent infection as well as models for the study of latency and pharmacological approaches to stimulate proviral gene expression.

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  • 这两种模型通过基因消融血管内皮生长因子- A发现侵袭性增加证实药理抑制剂结果

    Increased invasiveness is also seen by genetic ablation of the Vegf-A gene in both models, substantiating the results of the pharmacological inhibitors.

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  • 采用肾上腺素诱发清醒家兔心律失常结扎冠状动脉造成麻醉大鼠心律失常模型进行药理试验。

    Its antiarrhythmic effect is evaluated in conscious rabbit and anesthetized rat models of arrhythmia induced by epinephrine and coronary ligation.

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  • 应用动物模型研究了纯化毒素药理活性

    The pharmaceutical activities of the purified toxins were studied with animal models.

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  • 前期药理试验证明提物大鼠实验性缺血再灌注损伤模型(IR)明显保肝作用而且进一步的研究表明主要作用成分类。

    The primary experiment has revealed that its aqueous extract has obvious effects of liver protection based on IR model, and that the main functional components are nucleosides.

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  • 茱芡环烯醚菇总普总三部分大鼠、小鼠糖尿病模型进行了降糖作用药理实验,结果表明,二部分单用均降糖作用,合用效果明显。

    The pharmacological results revealed that both the active parts of iridoids and triterpenes acid had effects on decreasing blood glucose, though the joint use showed the better results.

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  • 方法口服给药,采用乙醇小鼠粘膜损伤模型冰醋酸大鼠胃溃疡模型、醋酸致小鼠疼痛模型、二甲苯致小鼠肿胀模型考察受试物药理作用

    Methods To investigate the pharmacological effect of IYC in rats and mice by oral administration, peptic ulcer and gastric mucosal damage model, ear swelling one, stomache one, and so on were adopted.

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  • 利用行为模型率先开展曲马朵槟榔嚼块提取物多药滥用的精神药理研究。

    Using behavioral sensitization animal models, poly-drug abuse about tramadol and betel quid extract was investigated in psychopharmacological profiles.

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  • 方法采用应激溃疡慢性乙酸溃疡大鼠模型观察舒胃散治疗慢性胃炎胃溃疡药理作用

    Methods:Taking some stress ulcer and chronic acetic ulcer rats as a model, observing Shuweisan s pharmacological action on treating chronic gastritis and stomach ulcer;

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  • 结论KM小鼠感染仙台病毒作为副流感病毒感染的疾病模型,应用于药理生物医学研究中

    Conclusion SV_infected KM mice can be used in model of anti_parainfluenza virus infected disease and pharmacology researches.

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  • 昆明物体识别模型具有简单快速可靠等特点可以安全药理研究中用来检测化学药物对记忆损伤。

    The object recognition task in KM mice, which is simple, rapid, and reliable, should be of great use in safety pharmacology to detect amnesic properties of new compounds.

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  • 目的中医指导建立SD大鼠阳虚便秘动物模型对其进行评价

    Aim To establish and evaluate Sprague-Dawley (SD) rats model with yang-deficiency and constipation at the direction of traditional Chinese medicine theories.

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  • 体外培养静脉内皮细胞做为研究血管模型对研究药理血管疾病重要作用进一步提供信息

    In vitro culture of human VSMC as a model of vascular research has played a critical role and continue to provide information in the pharmacology and therapy of vascular diseases.

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  • 血管平滑肌体外培养作为血管研究模型血管疾病治疗药理学研究提供信息发挥重要作用

    In vitro culture of human vascular SMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.

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  • 目的体外构建黑素细胞角质形成细胞直接接触混合培养模型观察白消一号对此模型中黑素瘤细胞的影响,探讨其治疗白癜风的药理作用。

    Objective to construct the mixed cultivating model of keratinocytes and melanoma cells, and to observe the effect of Baixiao Yihao decoction on melanoma cells.

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  • 方法:本实验采用环磷酰胺所致白细胞减少白鼠动物模型,研究海洋生物多糖FW-1模型小鼠外周血白细胞数,骨髓有核细胞数,免疫器官重量指标的药理作用。

    Results FW-1 could obviously increase the quantity of peripheral leukocytes of mice induced by CTX, so do the quantity of bone marrow cells and the weight of splenic organ and thymus.

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  • 目的观察三勒浆抗疲劳慢性疲劳大鼠模型多因素影响作用,为深入探讨药理学作用的机制奠定基础。

    Objective to observe the effect of chronic fatigue rat model which influenced by Sanajon oral liquid, to study the pharmacology mechanism.

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  • 方法:制造大鼠佐剂关节炎模型小鼠迟发性超敏反应(DTH)模型醋酸扭体疼痛模型,观察复方黑蚂蚁胶囊的药理作用。

    Methods: the adjuvant arthritis model of rats (AA rats), delayed hypersensitivity (DTH) model and the pain model induced by acetic acid in mice were used.

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  • 近年来定量药理中涉及模型仿真预测新药研发治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。

    Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.

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  • 近年来定量药理中涉及模型仿真预测新药研发治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。

    Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.

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