受体是药物筛选的重要靶标,基于受体的药物高通量筛选是药物筛选的主要类型之一。
The receptor is attractive as an important target for drug screening. Receptor-based high-throughput screening is one of the main techniques in modern drug discovery.
生物芯片是基因测序与表达、基因诊断、蛋白功能研究、药物高通量筛选的现代先进技术。
Biochip is an advanced technology for gene sequence determination, gene expression, gene diagnosis, protein function research, high through-put for candidate medicine.
本课题所研究的高通量药物筛选系统是集分离、分析和筛选于一体的自动化操作系统。
In our research, we make the high throughput screening system separate, analyze and filtrate drug at the same time.
这些光学特性使量子点在医学诊断、药物的高速筛选以及基因和蛋白质的高通量分析方面具有广泛的应用前景。
These advantages of the optical properties make them broad applications in medical diagnosis, high-speed screening drugs and high-throughput analysis of genes and proteins.
目的建立一种用于体外溶栓活性精确定量分析和高通量溶栓药物筛选鉴定的方法。
OBJECTIVE To establish a method for detecting and analyzing fibrinolysis activity in vitro and high throughput screening fibrinolysis drugs.
组合化学技术与高通量筛选技术相结合,在现代药物开发中已经起到了非常重要的作用。
Combined with high throughput screening, combinatorial chemistry has played a very important role in modern drug discovery.
本发明涉及一种适用于高通量药物筛选的蛋白质芯片,及其制备技术及其检测方法。
The present invention relates to a protein chip applicable to high-flux medicine screening process, its preparation technique and detection method.
方法建立稳定的GLP-1受体激动剂高通量筛选模型,从天然药物中筛选活性成分;在PC12细胞中验证GLP-1受体激动剂的功能及作用机制。
METHODS Natural products were collected to screen in the stable cell line of GLP-1 receptor, and the active component was identified in the PC12 cells.
药物鉴定:高通量筛选毒性药物和抗癌药物。
Drug Discovery: high-throughput screen for toxic and anticancer drugs.
荧光素酶报告基因分析技术在药物的高通量筛选中起着重要的作用。
Luciferase reporter gene technique plays an important role in high throughput screening.
探索高通量分析方法,进行氨基寡糖系列化合物的结构与代谢研究、药物动力学多合一筛选。
In exploring of high-throughput pharmacokinetic study, we profiled the isovalertatine family aminooligosaccharides and tried the cassette dosing in pharmacokinetic screening of drug candidates.
本发明的方法成本低、高通量、覆盖率高。可用于新型保护性抗原及药物靶标的筛选。
The method of the invention has low cost, high flux and high coverage rate, and can be used in the filtration of new protection antigens and medicine targets.
本发明的方法成本低、高通量、覆盖率高。可用于新型保护性抗原及药物靶标的筛选。
The method of the invention has low cost, high flux and high coverage rate, and can be used in the filtration of new protection antigens and medicine targets.
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