蛋白酶是一类重要的药物靶点。
他们需要病情恶化的模型，使他们能够查明药物靶点。
They need to model the progression of the illness so they can pinpoint drug targets.
他们的研究可能发现新的癌症治疗的药物靶点。
Their findings could lead to new drug targets for cancer therapies.
研究乳腺癌骨转移可为将来临床的预防和治疗提供新的药物靶点。
The study on breast cancer bone metastasis can provide new drug target for clinical prevention and treatment.
对老药作用机制的广泛的研究将为新近发现的药物靶点提供更多的证据。
Intensive study of the mechanisms of action of older drugs has provided further validation of several recently identified drug targets.
在宿主-寄生虫疾病中，像结核病，非同源蛋白质作为药物靶点是首选。
In host-parasite diseases like Tuberculosis, non-homologous proteins as drug target are first preference.
只有一个药物靶点两个基因作为HIV关键的蛋白点：逆转录酶和蛋白酶。
All but one of the drugs target two of the genes that serve as blueprints for vital protein components of HIV: reverse transcriptase and protease.
蛋白偶联受体具有重要的生理功能和病理意义，已成为一类重要的药物靶点。
Protein-coupled receptors are a group of drug targets with important physiological functions and of pathological significance.
G蛋白偶联受体具有重要的生理功能和病理意义，已成为一类重要的药物靶点。
G Protein-coupled receptors are a group of drug targets with important physiological functions and of pathological significance.
深入探索血吸虫功能基因可为该病的诊断、疫苗和药物靶点研究提供基础和依据。
Schistosome genes research provides the basis for study of schistosomiasis diagnosis, vaccine and drug targets.
噬菌体展示技术是一种有效的药物靶点筛选工具，可用其筛选中药的药物靶点蛋白。
The Phage display technology(PDT) is technology that expresses exogenic polypeptide with shell protein of phage by inserting the exogenic DNA into the shell gene.
大多数有效的药物靶点能够通过蛋白质相互作用网络分析，在大量非同源蛋白质间识别。
Most potent drug target can be identifying among large number of non-homologous protein through protein interaction network analysis.
生物化学加速了人类对于新的药物靶点的认识和识别，对于药物合成和发现都极有意义。
Biochemistry accelerated human drug targets for new knowledge and identification, drug synthesis and discovery are very meaningful.
而弄清楚这些分子的结构有助于科学家们去研究那些由畸形蛋白质引起的疾病，并找出更好的药物靶点。
Figuring out such structures could help scientists learn more about diseases caused by malformed proteins and identify better drug targets.
这些特征使FRA成为备受关注的药物靶点，已开发出一些FRA靶向药物并进入临床试验。
These features make FRA an attractive drug target, and several FRA-targeted drugs have been developed and are in phases of clinical testing.
它们在研究基因表达、基因识别、寻找药物靶点和探讨蛋白质结构与功能上都有着广泛的应用。
Meanwhile, they are widely applied to gene expression, gene identification, searching for drug targets and studying structure and function of proteins.
PKB是一新的、良好的抗肿瘤药物靶点，以PKB为靶点的药物开发已成为当前研究的热点。
PKB is considered as a novel and excellent target for antitumor chemotherapy and much attention have been paid to drug development based on PKB target.
结论CD147反义核酸能抑制卵巢癌的转移和成瘤，因而有可能成为卵巢癌的治疗的药物靶点。
CONCLUSION CD147 antisense RNA can inhibit invasion and tumorigenesis of ovarian cancer cells and CD147 may become a new drug target of tumor therapy.
好的蛋白结构分辨率对于对于很多应用都是非常重要的，包括但不限于虚拟筛选药物靶点与对接程序和蛋白质设计。
Better resolution is important for a number of applications, including but not limited to virtual screening of drug targets with docking procedures and protein design.
鉴于Chk1的抑制作用能够引起许多肿瘤细胞系的死亡，它已经成为肿瘤治疗中心的药物靶点(9)。
Chk1 has emerged as a drug target for cancer therapy as its inhibition leads to cell death in many cancer cell lines (9).
研究提示由于Chk1被抑制后会导致很多癌细胞死亡，Chk1可以作为癌症治疗的药物靶点(9)。
Research studies have implicated Chk1 as a drug target for cancer therapy as its inhibition leads to cell death in many cancer cell lines (9).
首次发现作用于细菌外壁令人琢磨不透的药物靶点详尽图像给科学家提供足够的新信息以帮助设计新型抗生素。
The first detailed images of an elusive drug target on the outer wall of bacteria may provide scientists with enough new information to aid design of novel antibiotics.
柯西奥期待这些文章能够促使研究关注于对胆固醇对眼睛的作用问题上，这可以帮助科学家确定潜在的药物靶点。
Curcio anticipates that these papers will prompt more research aimed at understanding the role of cholesterol in the eye, which could help scientists identify potential drug targets.
华盛顿大学圣路易斯医学院的科学家发现了一个新的药物靶点，该靶点能有效改善一些疑难癌症的放射疗法的疗效。
Scientists at Washington University School of Medicine in St. Louis have discovered a new drug target that could improve the effectiveness of radiation for hard-to-treat cancers.
这些有潜在价值的用于HCC诊断和预后的分子标记物和治疗的药物靶点，能够给HCC的诊断和治疗带来新的动力。
These promising diagnostic and prognostic molecular biomarkers as well as therapeutic targets may bring new energy for the diagnosis and management of HCC.
在药物基因组学，临床生物信息学由生物信息学工具和药物靶点的鉴定、临床验证相关的蛋白质组学等多方面研究组成。
In pharmacogenomics, clinical bioinformatics includes elaborate studies of bioinformatics tools and various facets of proteomics related to drug target identification and clinical validation.
筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。
We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.
在MLL白血病一个临床前鼠模型中，抑制GSK3可提供有效性的令人鼓舞的证据，并标记了GSK3作为候选的癌症药物靶点。
Inhibition of GSK3 in a preclinical murine model of MLL leukaemia provides promising evidence of efficacy and earmarks GSK3 as a candidate cancer drug target.
尽管毒性不是很大，这些药物通常需要在癌症病人身上进行试验，因为该药物的靶点仅表现在病人身上。
Although not very toxic, these drugs often need to be tested in cancer patients, since the target of the drug is expressed only in these patients.
另外，在非肿瘤治疗领域，随着从分子生物学角度更好的理解疾病，对于特定靶点药物的研究有所增加。
Also, in nononcologic therapeutic areas understanding the molecular biology of the disease increases; thus, the chances of developing specific targeted drugs increase.
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