用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.
另外，我们的模型整合机制使药物从聚合物基质中释放的过程可以被定量分析。
Furthermore, our model incorporates mechanisms by which the processes underlying drug release from a polymer matrix can be quantitatively analyzed.
方法采用无膜溶出模型，考察释放面积、振荡频率对眼用凝胶溶蚀及药物释放的影响。
Methods The non-membrane model was introduced to observe the influence on the drug release and gel erosion for surface area and shaking frequency.
这项研究集中在药物从PLGA圆筒型微囊中释放的数学模型。
This study focuses on mathematical modeling of drug release from PLGA cylindrical millirods.
以组分的连续性方程为基础，建立了药物从多孔骨架聚合物系统中释放的数学模型。
A mathematical model describing the drug release from porous polymer was established by using the species continuity equation.
以维生素b12为模型药物，研究药物的释放性质。
Vitamin B12 was selected as a model drug and the in vitro release properties was studied.
提出一种新型的胶囊式药物释放微机电系统的设计模型。
模拟不同载药量对药物释放速率的影响并与其它数据进行比较，以此来验证此模型。
The effects of different drug loadings on the drug release rate were simulated and compared with other data to validate this model.
以茶碱为模型药物，模拟体外释放的结果表明，共聚物胶束对茶碱的体外释药可分为突释、缓慢释放、平衡释放三个阶段。
The vitro release result which used theophylline as model drug showed, the release behavior can divide to sharp release , relaxedly release and equilibrium release periods.
对模型参数的最佳评价通过最小化模型模拟和实验测定间的药物释放动力学差别来获得。
Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.
并选用盐酸黄连素为模型药物进行包衣片剂的体外释放试验。
Berberine chloride was chosen as model drug to prepare coating tablets.
目的：以磷酸川芎嗪为模型药物制备了脉冲释放片，并考察其体外释放的影响因素。
Objective: to prepare tetramethylpyrazine phosphate pulsed-release tablets and subsequently to characterize factors to affect the pulsed release of tetramethylpyrazine phosphate in-vitro.
目的用人工神经网络模型定量的预测HPMC的量和其固有黏度对药物释放的影响。
Objective To use ANN to quantitatively predict the influence of the amount of HPMC and its internal viscosity on allopurinol release from HPMC sustained release tablets.
在模型中引入相对渗透速度来刻画药物释放过程中不同机理的影响，并用摄动方法对方程进行了求解。
The relative permeating rate was introduced to describe the effects of the different physical processes. An asymptotic solution has been obtained by using the perturbation theory.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
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