鼻腔给药是一种极具潜力的药物转运系统。
除蛋白质类药物外,胞饮在药物转运过程作用不大。
Pinocytosis probably plays a minor role in drug transport, except for protein drugs.
本发明涉及碳纳米管作为载体在抗癌药物转运中的应用。
The invention relates to the application of carbon nanotubes in the transport of anti-cancer drugs as carriers.
肝脏药物转运体1B1基因多态性与他汀类药物致肌病有关;
The polymorphisms of liver drug transporter 1B1 genes are associated with myopathy induced by stating.
本文以风湿性疾病常用的治疗药物为主线,归纳了近年来影响药物疗效中有关药物代谢酶、药物转运体和药物作用靶点的基因组学研究进展。
The progress of pharmacogenomic research in the effects of drug treatment on rheumatic diseases could prevent adverse reactions, and provide reasonable guidance to clinical treatment.
对这些转运蛋白的研究使人们能深入地解析药物在血脑脊液屏障上的动态,更有效地调控药物转运行为,指导脑靶向与非脑靶向药物的研发设计。
Study on these transporters could attribute to elucidate the action of the drug at the BCSFB, regulate the drug transport behavior and guide the research & d…
由于核苷酸切除修复、药物转运和药物代谢通路在铂金药物功能中的重要性,这篇综述重点总结了这些通路中的基因表达和非癌细胞DNA变异与铂金疗效的关系。
We focused on several key pathways, including nucleotide excision repair, drug transport and metabolism. Both expression and germline DNA variation were evaluated in these key pathways.
《国际糖尿病》:为检验药物在改善胆固醇逆向转运(RCT)方面的效果,我们需要对RCT进行评估,在RCT检测方法我们面临的挑战是什么?
INTERNATIONAL DIABETES: We need to assess RCT (reverse cholesterol transport) in order to measure the effect of drugs on promoting RCT. What is the major challenge of the methods?
身体吸收、转运、代谢、或分泌一种药物或其代谢物的速率。
Pharmacokinetics --- The rate at which the body absorbs, transports, metabolizes, or excretes a drug or its metabolites.
口服是最常用的给药途径,其吸收涉及药物通过胃肠道上皮细胞膜的转运。
For oral administration, the most common route, absorption refers to the transport of drugs across membranes of the epithelial cells in the GI tract.
药物可通过被动扩散、易化被动扩散、主动转运或胞饮作用等方式穿越生物屏障。
Drugs may cross a biologic barrier by passive diffusion, facilitated passive diffusion, active transport, or pinocytosis.
专家们在文中写道:这项研究揭示了一种新型蛋白转运装置的属性,因此为抗疟药物研发者提供了一个新的靶点。
"This study reveals the identity of a novel protein trafficking apparatus... and hence, provides an 'Achilles heel' for anti-malaria drug developers," they wrote.
肠道转运体、肝脏药物代谢酶及肾脏在药物adme过程中发挥着重要作用。
Intestinal drug transporters, hepatic drug metabolic enzymes and the kidney play a very important role in the process of ADME.
与其它类型抗抑郁药物相比,抗抑郁药物物联合高效血清素转运体抑制剂与卒中风险增高相关。
Use of antidepressants with high inhibition of the serotonin transporter was associated with a greater risk for stroke than use of other types of antidepressants.
在接受放射性药物123i - FP - CIT注射3小时后,患者进行了单光子发射断层扫描(SPECT)成像评估基线多巴胺转运体功能。
Three hours after receiving an injection of the radiopharmaceutical 123i-fp-cit, patients underwent single-photon emission tomography (SPECT) scanning to assess baseline dopamine transporter function.
研究者还发现,柚皮素能拮抗药物摄取的关键转运体,OATP1A2,它能使药物从小肠转运到血液中。
The team also found that naringin appeared to block a key drug uptake transporter, OATP1A2, which has a role in transporting drugs from the small intestine into the bloodstream.
结论肾脏脂肪囊可以作为药物的贮存及向肾组织内转运的场所。
Conclusion The renal adipose capsule can be acted as the place of medicine storing and releasing into the kidney.
本文概述了近年来转铁蛋白在蛋白多肽药物口服给药中的作用及有关转运机制的研究进展。
In this paper, the progress of transferrin applied in protein and peptide peroral delivery is reviewed, and the transportation mechanism of transferrin is also discussed.
药物代谢酶、转运体及药物作用靶点存在着的基因多态性与药物疗效和毒性的个体差异有很大关系。
The genetic polymorphism of drug metabolizing enzyme, transporter and target greatly influence the individual difference of drug efficiency and toxicity.
本文对肾脏转运蛋白的分类、种属差异、以及可能产生的与抗生素有关的药物间相互作用进行综述。
This review focuses on the classification of renal transporters, species differences, and the possible drug-drug interactions caused by renal transporters.
结论:空白压敏胶对药物从贮库向皮肤转运有一定程度的阻滞作用。
CONCLUSION: the blank pressure sensitivity adhesive prevented drug from reservoir toward skin, and the transdermal enhancers enhanced the drug releasing speed.
结果纳米颗粒转运系统能够保护被转运的基因,有较高的转染效率,具有良好的靶向性,并且提高了药物的生物利用度,显示出一定的缓控释作用。
Results Nanoparticle carrier system can protect the genes, have a high carrying efficiency and a well targeting property, it also can improve the bioavailability, sustained and controlled release.
由于转运蛋白的特异性之间存在重叠,药物在肾小管分泌过程中产生的药物的相互作用将是今后临床上值得注意的问题。
Due to overlapping specificities of the transport proteins, drug interactions at the level of tubular secretion is an event that may occur in clinical situation.
A BCG2是半ATP结合盒转运体。它可以转运内源性物质和人工合成的抗肿瘤药物等多种底物。
ABCG2 is a half ATP-binding cassette (ABC) transporter that facilitates efflux of a wide variety of substrates ranging from natural products to synthetic anticancer drugs.
现从药物由鼻腔到脑的转运方式、影响因素、剂型、评价方法以及增强脑靶向性的方法等方面,对近年来鼻腔给药脑靶向性的研究进展进行综述。
Advances on drugs transport pathway from nasal cavity to brain, factors affecting the transport of drugs, types of dosage forms and evaluation tools of the brain-targeted nasal delivery system we...
现从药物由鼻腔到脑的转运方式、影响因素、剂型、评价方法以及增强脑靶向性的方法等方面,对近年来鼻腔给药脑靶向性的研究进展进行综述。
Advances on drugs transport pathway from nasal cavity to brain, factors affecting the transport of drugs, types of dosage forms and evaluation tools of the brain-targeted nasal delivery system we...
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