除了肝脓肿和肉芽肿病外，药物肝毒性容易被忽视。
In addition to liver abscesses and granulomata, drug hepatotoxicity is likely underappreciated.
体外培养的原代肝细胞被广泛用于药物代谢、药物间相互作用和药物肝毒性的研究。
Primary cultures of hepatocytes have been extensively used for evaluation of drug metabolism, drug-drug interactions and drug hepatotoxicities.
这种情况通常出现在某些存在不可预知肝脏毒性的药物中，而且可能导致一些患者出现急性肝衰竭。
It is often associated with a drug of unpredictable liver toxicity, and may be the cause of acute liver failure in some patients.
研究发现至少20%的中毒性肝损伤摄取过一种以上的潜在肝损伤药物。
The study found that at least 20 percent of patients with DILI ingest more than one potentially hepatotoxic agent.
实验结果表明，酮康唑在一定剂量下可导致药物中毒性肝损伤。
The results indicate that Ketoconazole can cause drug toxic hepatic damage at a certain dosage.
目的：药物诱发肝毒性的新认识。
Objective: To reveal the new recognition of drug-induced hepatotoxicity.
结果：药物性肝炎多发生于长期、联合使用有肝毒性的药物而又无肝功监测的患者，多见于农民及工人。
Results:Most of the drug hepatitis happen in the patients with long-termly, combined use hepatotoxic drugs without liver function monitor, and most of the patients are peasants and workers.
结论；茴三硫治疗慢性病毒性肝炎、药物性肝炎等慢性肝损害，可以明显减轻患者症状，改善肝功能，其疗效与硫普罗宁效果相近，临床观察无明显不良反应。
Conclusion: anethol trithione can improve the symptoms and liver functions without unbearable side - effects in the patients with chronic hepatopathy as well as the tiopronin dose.
肝毒性主要集中在寒、热类，苦、辛类，归肝、脾、肾经类和有效成分中碱、甙类药物方面。
HTX mainly occurs among the herbs that are cold or heat in property, bitter or acrid in taste, distribute to liver, spleen or kidney channel and their ac including alkaloids, glycosides, etc.
药物诱导的肝毒性被证明存在于15%的患者中，但实际的发生似乎更为频繁。
Drug-induced hepatotoxicity was documented in 15% of patients but likely occurred more frequently.
结果：中药中寒温性药物、苦辛甘味药物、归肝肺经药物居多，有肝毒性中药也有这种趋势，肝毒性中药与一般中药在四气五味归经方面分布趋势大致相同。
Results:Herbs mainly occurs among the herbs that are cold or warm in property, bitter or acrid or sweet in taste, distribute to 1iver, lung channel. HTX Herbs trend it too.
结果：中药中寒温性药物、苦辛甘味药物、归肝肺经药物居多，有肝毒性中药也有这种趋势，肝毒性中药与一般中药在四气五味归经方面分布趋势大致相同。
Results:Herbs mainly occurs among the herbs that are cold or warm in property, bitter or acrid or sweet in taste, distribute to 1iver, lung channel. HTX Herbs trend it too.
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