• 结果中西降糖复方的降糖作用明显增强缓解高血糖带来的高脂血症等不良反应,且药物的毒性作用大大降低

    RESULT The compound prescription for reducing blood sugar had markedly enhanced effect, could relieve hyperlipemia caused by hyperglycemia and its toxicity was greatly reduced.

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  • 然而目前以化疗药物为主的方法很多健康细胞带来毒性往往病人造成严重作用

    However, current chemotherapy drugs administered in this fashion are toxic to many healthy cell types, often resulting in severe side effects for the patient.

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  • 病人(特别是老年病人)经常性使用一种以上治疗药物话,往往发生产生毒性药物相互作用

    When a patient, particularly the elderly is prescribed frequently to take more than one therapeutic agent, drug interactions resulting in toxicity will occur.

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  • 例外的是,这些药物临床明显药物作用——贝伐单抗可致高血压,吉非替尼厄洛替可有皮肤毒性

    Fortuitously, these drugs also have clinically obvious pharmacodynamic end points-hypertension for bevacizumab and skin toxicity for erlotinib and gefitinib.

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  • 结果四个方程来源于三类数学体系(统计,量效关系极值),它们能有效帮助我们评价药物等的临床作用毒性情况。

    Results: Four equations related with probability, dose-responses and extreme data are useful way to evaluate the effects and toxicity of drugs in the clinics.

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  • 叙述维生素药物作用及其婴幼儿中的应用提示注意维生素类药物的毒性反应

    The action of vitamin medicine and its application to infants are presented. It also called on the attention on toxic reaction of vitamin medicine.

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  • 用得不当;则可能毁了人类。病人特别是老年病人经常性使用一种以上治疗药物话;往往发生产生毒性药物的相互作用

    When a patient, particularly the elderly is prescribed frequently to take more than one therapeutic agent, drug interactions resulting in toxicity will occur.

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  • 药物代谢转运体药物作用靶点存在着基因多态性与药物疗效毒性个体差异有很大关系

    The genetic polymorphism of drug metabolizing enzyme, transporter and target greatly influence the individual difference of drug efficiency and toxicity.

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  • 药物代谢(DME)药物代谢解毒药物代谢活化中起重要的作用组织器官的药物效应和毒性易感性产生重要影响

    Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity.

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  • 目的探讨护理干预外用药物联合减少奥沙利铂引起神经毒性反应的作用

    Objective:To evaluate a combined intervention of nursing and dru gs on neurotoxicity in oxaliplatin chemotherapy for gastric cancer patients.

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  • 目的观察参芪扶正抗蒽环类药物化疗所致心脏毒性作用

    Objective To observe the heart protection effect of parenteral solution Shenqifuzheng in the chemotherapy with marcellomycin.

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  • 掌握有毒中药去除毒性方法配伍正确使用相杀作用,消除药物毒副反应

    Should have a method of detoxification of toxic Chinese medicines, the proper use of the compatibility slay role in removing the drug toxicity.

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  • 药物靶向肾脏不仅降低毒性,而且能增加药物肾脏作用效果

    Selective targeting of drugs to kidneys may enable an increased renal effectiveness combined with a reduction of extrarenal toxicity.

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  • 1997年来因医疗失误药物作用造成药物不良反应,即药物毒性反应造成的死亡人数已经超过原来的2上升了131%。

    The number of deaths from adverse drug reactions - negative responses to medicines resulting from medical error or side-effects - has more than doubled since 1997, rising by 131 per cent.

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  • 药物相互作用引起药物不良反应药源疾病常见原因有些恰当药物联合会造成严重毒性反应,甚至导致死亡

    Drug interaction is one of common cause for drug adverse reaction or drug induced disease. Sometimes, irrelevant compatibility of drugs may cause severe toxic reaction, or may induce death.

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  • 通过药物组合物包含LL - 37的生长培养基包括双层性极性脂质,具体为双乳糖基甘油二酯,降低LL - 37的细胞毒性作用

    The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.

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  • 这些药物可能经典镇痛剂内在镇痛活性潜在活性,或减低经典镇痛剂的毒性作用

    They may have an intrinsic analgesic activity or may potentiate the activity of classical analgesics or diminish their toxic effects.

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  • 体外培养原代细胞广泛用于药物代谢药物相互作用药物毒性的研究。

    Primary cultures of hepatocytes have been extensively used for evaluation of drug metabolism, drug-drug interactions and drug hepatotoxicities.

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  • 结果通过介入化疗药物治疗选择作用机制不同的各种肿瘤敏感性药物联合使用,使其细胞毒性作用协同作用增加

    Results Choosing the joint application of tumor sensitive drugs of different mechanism through the treatment of chemotherapeutics, can increase the synergy of cytotoxic effects without side effects.

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  • 目前恶性肿瘤药物治疗中是以化学药品为主,化学药品开发费用昂贵毒副作用,多不同程度的突变毒性

    Now, chemicals are the capital therapeutics to cure malignancy, but the exploitation cost of chemicals is expensive, it has big adverse reaction and most of it have mutagenesis noxious property.

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  • 第一、二抗组药易与多种药物发生相互作用而致心脏毒性不良反应,第三代抗组胺药联用不会导致严重的不良反应

    The third generation of antihistamines seems no such severe cardiotoxicity reported. This introduction discussed the adverse reactions of antihistamines commonly used as OTCs.

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  • 治疗方案能够防止HIV 病毒耐药产生减少单一作用靶点药物用药剂量降低相应毒性,最终治愈AIDS相关的病理学变化

    This approach could prevent the development of drug-resistant HIV strains and decrease the dosage and related toxicity of each single drug and lead to a cure for AIDS-associated pathologies.

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  • 这些疗法与药物疗法具有同等作用并且另有毒性好处

    These can be just as useful as drugs, and have the added benefit of being nonpoisonous.

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  • 药物代谢过程影响药物发挥作用产生毒性过程。

    The process of drug metabolism is such which may exert influence on the development of the effectiveness and the production of the toxicity of drugs.

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  • 食物药物相互作用降低增加药物效应,可能引起治疗失败药物毒性增加。

    Interactions between food and drug may alter the drug therapeutic effects, and result in treatment failures and increased toxicities.

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  • 迫切需要建立检测方法预测化疗药物病人个体疗效毒性作用。将胃癌细胞持续暴露于抗肿瘤药物,能够使得细胞获得耐药的表型。

    A method for predicting efficacy or toxicity of anticancer drugs for individual patients is one of the most critical issues to be solved in regard to cancer chemotherapy.

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  • 然而LDN和顺箔一起作用时,可以减少毒性显示LDN对于化疗药物所产生不良作用有缓解的效果。

    However, LDN in combination with cisplatin attenuated the toxicity of this chemotherapeutic agent, indicating that LDN was protective of the adverse events elicited by a chemotherapeutic drug.

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  • 摘 要:目的探讨蜂胶提取物抗肿瘤减轻化疗药物毒性作用

    Purpose: To study propolis extract antitumor effect and its lowering of the toxicity caused by chemotherapeutant.

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  • 摘 要:目的探讨蜂胶提取物抗肿瘤减轻化疗药物毒性作用

    Purpose: To study propolis extract antitumor effect and its lowering of the toxicity caused by chemotherapeutant.

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