药物的作用机制究竟是什么?
摘要:本文概述了抗病原真菌药物的作用机制、研究现状和发展趋势。
Abstract: The mechanism of action, investigative situation and development trend of antifungal drugs were summarized.
本文介绍了常用抗血小板药物的作用机制以及指南性建议和临床试验证据。
This article introduces the mechanism of currently available antiplatelet drugs as well as their practice guidelines and evidence from clinical trials.
不难想象,这些药物的作用机制与安慰剂效应产生时大脑中所发生的变化有相似之处。
It is not hard to imagine a similarity between the workings of these drugs and what happens in the brain when the placebo effect is operating.
这些药物的作用机制是阻断酪氨酸激酶启动信号级联反应,后者可以促进肿瘤细胞生长。
The drugs work by preventing an enzyme called tyrosine kinase from launching a signaling cascade that fuels tumor cell growth.
科学家称,这些药物的作用机制可能是通过缓解动物免疫系统过激,进而阻止对胰腺的损伤。
The scientists say that the drugs appeared to work by soothing the animals' over-active immune system, which in turn stopped damaging the pancreas.
药物的作用机制尚不清楚,可能的作用包括血管收缩、调节信号传导通路和促进内皮细胞凋亡。
The drugs' mechanism of action remains uncertain, but plausible theories include vasoconstriction, modulation of pro-survival signal transduction pathways, and endothelial cell apoptosis.
对化疗前后的肿瘤组织进行电镜观察,初步探讨在给予最佳局部化疗药物时化疗药物的作用机制;
The mechanism of VCR was investigated rudimently by comparing the electron microscope presentation of tumor before and after chemotherapy.
目的:介绍口服降糖药物的种类和主要作用,重点介绍胰岛素抵抗改善药物的作用机制和开发动态。
Objective: To introduce the types and main roles of oral hypoglycemic drugs, emphasizing on the action mechanism and developmental trends of insulin sensitizing agent.
一般认为,青蒿素类药物的作用机制与其结构中的内过氧桥有关,最近又提出一些与以往不同的观点。
It is generally agreed that artemisinins action mechanism is associated with the endoperoxide function, but some researchers have some other ideas.
与众不同之处在于这类药物的作用机制是基于肠促胰岛素GLP-1的,GLP-1是在餐后分泌的。
What makes it different is that it is based on the incretin hormone, GLP-1, which is secreted after a meal.
综述了近年来抗血栓药物中生化药物的作用机制,临床应用以及优缺点,为寻找安全、有效的新抗栓药物提供参考。
In this paper, the antithrombotic action and clinical application of biochemical drugs were introduced, the advantages and disadvantages of different biochemical drugs were also reviewed.
直到现在二甲胺四环素药物的作用机制仍不是十分清楚,SFVAMC神经康复学主要研究员Raymond A。
The way in which minocycline works has been very unclear until now, says principal investigator Raymond A. Swanson, MD, chief of neurology and rehabilitation at SFVAMC.
两类药物的作用机制是不同的,但至少我们知道DPP - 4抑制剂和磺脲类同样有效,我想这也是临床经验得到的共识。
There are differences in mechanism of action certainly but the bottom line is that we know it works as well as sulfonylureas and I believe that has been the consensus from clinical experience.
Julio Rosenstock博士表示目前用于2型糖尿病的药物往往会造成体重的增加,但是利莫那班与目前使用的口服糖尿病治疗药物的作用机制不同。
Rosenstock says current medications for type 2 diabetes are often associated with weight gain but Rimonabant has a different mode of action from the oral anti-diabetic medications presently used.
在这些细胞里,它们被一种尚未被人类完全认识的机制保护着从而免受药物作用。
In these cells it is protected from the drugs by mechanisms that are, as yet, not fully understood.
这是因为只要降压药物能够在大多数病人身上起作用,不会引起不良反应,其内在的分子机制并不令人感兴趣。
That's because as long as antihypertensive drugs work in the majority of patients without causing bad side effects, their underlying molecular mechanisms are not as interesting.
目标之一是试图弄清楚通过外科手术可以快速消除糖尿病的激素作用机制,若如此,未来研制的药物可能也会有同样的效果。
One goal is to try to figure out the hormonal mechanisms by which the surgery can quickly resolve diabetes, so that drugs might one day be developed to have the same effect.
两种药物相互作用产生这种结局的机制尚不清楚。
Exactly how the two drugs interact to produce this result is not yet clear.
但是,爱人的照片是在大脑内完全不同的区域里发生作用的——大脑原始的回报机制区域会发光,而那里正是上瘾药物发作时大脑会发光的区域,这也是为何类鸦片止痛药会发挥奇效。
But, the love photo acted in a totally different area of the brain-the primitive reward system region that lights up where addictive drugs work, and where pain-relieving opioids do their magic.
另外一些药物有不同的作用机制。
通过联合施用作用机制不同和药效时段不同的药物,ACTs加大了未被一种药物杀死的任何寄生虫被第二种药物杀死的可能性。
By combining drugs with different mechanisms of action and different time spans of activity, ACTs increase the likelihood that any parasites not killed by one drug will be killed by the second one.
正是这种双重作用机制使我们有理由相信PI- 88有潜力成为目前肿瘤治疗的新型替代药物。
It is by this dual mechanism of action that we believe PI-88 has the potential to be any exciting alternative to current cancer treatments.
棘白菌素是一类新型抗真菌药物,具有全新的作用机制。
The echinocandins are a new class of antifungals with a novel mode of action.
因此,可以设计靶向细菌叶酸合成机制的药物,不会在人身上引发副作用。
Therefore, it's possible to design drugs that target the bacterial folate machinery that would not lead to side effects in humans.
与其他的抗糖尿病药物比较,DPP - 4抑制剂有哪些独特的作用机制?
What is the special mechanism of action with the DPP-4 inhibitors that is unique among anti-diabetes therapies?
对端粒酶活性的抑制可能是两种药物发挥抗肿瘤作用的机制之一。
The inhibition of telomerase activity may be one of the mechanisms of the anti-cancer effect of the two drugs.
请您给我们介绍一下抗肝纤维化药物对于肝星状细胞的可能的作用机制?
Would you please give us a brief introduction on the possible strategies to target HSCs using anti-fibrotic agents?
请您给我们介绍一下抗肝纤维化药物对于肝星状细胞的可能的作用机制?
Would you please give us a brief introduction on the possible strategies to target HSCs using anti-fibrotic agents?
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