• 增加药物溶解度溶出速率齐墩果酸制剂研究中的主要措施。

    One of the most powerful means in the development of oleanolic acid new dosage forms is to increase its solubility and drug dissolution velocity.

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  • 纳米不仅能提高药物溶解度具有体积小等优点,因而药物静注纳米混悬剂的研发日趋增多

    Nanoparticles not only enhance the solubility of drug, but also lower the volume of injection. These have led to increasing research and development activities for intravenous nanosuspensions.

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  • 介绍了静脉注射脂肪乳剂提高药物溶解度稳定性减轻药物不良反应缓释靶向给基因治疗等方面研究进展。

    The progress of drug loaded intravenous lipid emulsions in enhancing drug solubility and stability, reducing side effects, sustained release, targeted delivery and gene therapy is introduced.

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  • 表面活性剂通过增加药物的吸湿性、溶解度分散性来增加溶解速率

    Surfactants increase the dissolution rate by increasing the wetability, solubility, and dispersibility of the drug.

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  • 结果通过一些特殊传递方法策略可以解决树碱类药物所存在溶解度稳定性、毒性不良反应问题

    Result the problems of camptothecin such as solubility, stability and side effects could be solved by special delivery methods and strategies.

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  • 大分子载体系统可以用来提高这些这些药物溶解度

    MacromoIecular carriers can be used to augment the solubility of such drugs.

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  • 目的通过诺氟沙星-PVP沉淀物研究提高药物出度和增大溶解度提供一些参考

    Objective: The authors studied norfloxacin PVP coprecipitate in order to provide references for difficult soluble drug to improve dissolution.

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  • 由于CH331一种新型抗癌药物性质研究的报道几乎没有,因此首先测定了其不同介质中的溶解度以达到更好的效果

    Since CH331 is a novel antitumor agent, data is lacking on its physical and chemical character. It is necessary to study its solubility in different media for effective encapsulation.

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  • 药物溶解度与其吸收密切相关

    There exists an important relationship between the water solubility of drugs and their absorption.

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  • 结果:同一药物不同显示各自不同的结构图形、溶解度生物有效度的特性。

    Results:Each polymorphic form solid has it's x ray powder diffraction pattern and this different solid form shows different stability, formulability and bioavailability.

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  • 纳米混悬液可增大难药物溶解度提高药物有效性安全性等。

    Nanosuspensions not only solve the problems of poor solubility and bioavailability but also improve the efficacy and safety of drugs.

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  • 纳米混悬液可增大难药物溶解度提高药物有效性安全性等。

    Nanosuspensions not only solve the problems of poor solubility and bioavailability but also improve the efficacy and safety of drugs.

    youdao

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