目的研究第一代药物洗脱支架治疗冠心病远期(5年)临床疗效。
Objective To study the incidence of major cardiovascular events by observing the clinical outcome of the first-generation drug-eluting stents (DES) 5 years after implantation.
药物洗脱支架置入是目前治疗冠心病的主要方式,但血栓形成仍是目前关注的主要问题。
The implantation of a drug-eluting stent is one of the main methods for treating coronary heart disease, but the occurrence of thrombogenesis after implantation remains a problem.
《循环》杂志提前在线刊物中的科学咨询也讨论了不同种类的支架,同时提到药物洗脱支架有利也有弊。
The Science Advisory, which appears in an advance online publication by the journal Circulation, also discusses different types of stents, noting that DES are both "good and bad".
新一代药物洗脱支架由可吸收多聚物为平台,具有与金属支架相当的的支撑力,以及良好的生物相容性。
Bioabsorbable polymers have been used as the platform of a novel coronary stent, which has strength comparable to stainless steel stents and biocompatibility with the vessel wall.
昨日一个热点会议发布,新的研究数据表明与药物洗脱支架(DES)有关的急性冠状动脉综合征死亡率不断增加。
NEW DATA showing increased mortality rates associated with drug eluting stents (DES) in acute coronary syndromes were presented in a Hot Line Session yesterday.
国际循环:目前对于无保护左主干病变,究竟是置入药物洗脱支架还是CABG治疗对患者获益更大还存在争议。
International Circulation: This leads into my next question. For patients with left main lesion or multi-vessel lesions, obviously there are different opinions on CABG or drug-eluting stents.
目的:探讨ST段抬高性心肌梗死患者经皮冠状动脉介入置入雷帕霉素药物洗脱支架内血栓形成的相关因素及预后。
Objective to study the related factors and prognosis of rapamycin drug-eluting stent thrombosis after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.
背景:与中心随机对照试验相比,在广泛的“真实世界”患者中应用更多的药物洗脱支架的安全性和有效性具有争议。
Background: The safety and efficacy of drug-eluting stents among more generalized "real-world" patients than those enrolled in pivotal randomized controlled trials are controversial.
接受药物洗脱支架的患者长病变和复杂病变比接受裸金属支架的患者多,而且接受双重抗血小板治疗1年的可能性较大。
DES recipients had longer and more complex lesions than BMS recipients and also were more likely to be receiving dual antiplatelet therapy at 1 year.
目的比较冠心病患者弥漫病变采用药物洗脱支架和金属裸支架治疗的近期和远期预后,分析影响这类病变介入治疗预后的危险因素。
Objective Compare drug-eluting stent (DES) to bare-metal stent(BMS) in prognosis on treating diffuse coronary lesions and analysis risk factor of treating complex and diffuse lesions in PCI.
目前,对于接受药物洗脱支架的患者,我们尝试维持双重抗血小板治疗在一年以上,因为我们非常关注晚期支架内血栓形成的可能性。
Right now, we try to keep dual anti-platelet therapy going for up to one year in patients who have a drug-eluting stent because we are very concerned about the possibility of late-stent thrombosis.
目前一项最大的药物洗脱支架(DES)与金属裸支架(BMS)长期研究显示,植入DES的患者死亡率并未高于植入BMS的患者。
Mortality rates in patients with drug eluting stents (DES) are no higher than with bare metal stents (BMS), according to the largest ever long-term study of DES and BMS.
对GRACE研究结果的评论中,Steg认为在通过长期试验进一步发现安全性证据之前,STEMI患者应谨慎使用药物洗脱支架。
Commenting on the GRACE findings, Steg said: "DES should be used cautiously in STEMI patients until there is further safety evidence from longterm trials."
这篇文章中说,对于药物洗脱支架置入的患者,支架内血栓形成是和早期停用抗血小板紧密相关的主要副作用,其死亡率为20%到50%。
The paper says that stent thrombosis is the "leading adverse event" associated with early antiplatelet discontinuation in patients with DES and carries a mortality rate of 20-45%.
冠脉旁路移植术组校正后死亡率低于药物洗脱支架组,在3支血管病变组(危险比0.80)和2支血管病变组(危险比0.71)均如此。
Adjusted mortality was lower with CABG than with DES, both in patients with 3-vessel disease (HR, 0.80) and in those with 2-vessel disease (HR, 0.71).
愈合的不均一性在有lst证据的药物洗脱支架中很常见,这种不均一性也证实了支架部分不完全愈合在LST发病的病理生理学上的重要性。
Heterogeneity of healing is a common finding in drug-eluting stents with evidence of LST and demonstrates the importance of incomplete healing of the stented segment in the pathophysiology of LST.
总共804名成功植入西罗莫司或紫杉醇药物洗脱支架的病人,检查了他们在服用了600mg负荷计量的氯吡格雷之后的治疗后血小板活性。
A total of 804 patients who had successful sirolimus- or paclitaxel-eluting stent implantation were assessed for post-treatment platelet reactivity after a loading dose of 600 mg of clopidogrel.
药物洗脱冠脉支架的长期安全性和有效性尚存疑问。
Background The long-term safety and efficacy of drug-eluting coronary stents have been questioned.
在基线水平两组之间血管造影结果相似。支架在两个月的时间内有完全相同的生物学可降解的多聚物涂层和洗脱药物。
Both groups had similar angiographic characteristics at baseline. The stents had an identical biodegradable polymeric coating and eluted drugs over a 2-month period.
在基线水平两组之间血管造影结果相似。支架在两个月的时间内有完全相同的生物学可降解的多聚物涂层和洗脱药物。
Both groups had similar angiographic characteristics at baseline. The stents had an identical biodegradable polymeric coating and eluted drugs over a 2-month period.
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