基于药物基因学，300名患者中的93%被FDA认定变异将影响药物的使用；
Regarding pharmacogenes, 93% of the 300 patients carried variants recognized by the FDA to affect drug use;
除了基因组学、蛋白质组学和代谢组学，科学家还在使用化学基因组学，这是一种逆转标准的药物发现过程的方法。
As well as genomics, proteomics and metabolomics, scientists are also using chemical genomics, an approach that reverses the standard drug discovery process.
一个回报丰厚的领域就是药物基因组学。
这一模式是随着基因学研制出新一代的药物而重复出现。
This is a pattern seen again and again with the new generation of drugs that genomics has helped to create.
药物基因组学能改进疟疾药物政策吗？
基因学的热衷者们对发表在《柳叶刀》上的该研究论文大肆追捧，认为这是最终为开发出个性化药物所迈出的重要一步。
Genomics enthusiasts hailed the paper, published in the Lancet, as an important step toward personalized medicine.
但是CuraGen的股票，博士和Rothberg的财富，迅速下降，当投资者意识到，基因组学是不会导致新的药物过多。
But CuraGen's shares, and Dr. Rothberg's wealth, fell rapidly when investors realized that genomics was not going to lead to a plethora of new drugs.
但是他说，对这些基于小鼠内的基因学研究的一类新型药物下结论还为时过早。
But he said it is too early to draw conclusions about this new class of drugs based on a genetic study in mice.
即便是生产和推广已经成功的药物基因组学产品的产家也在不断面临着困难。
Even companies manufacturing and marketing already successful pharmacogenomic drug-test combinations continue to face difficulties.
药物基因组学：预示了充满希望的未来以及回顾性的临床试验设计，FDA可能会为实现管理型决策的目的而批准后者。
Pharmacogenomics: Delivering on the Promise considers prospective versus retrospective clinical trial design and when, if ever, the FDA might allow the latter for regulatory decision-making purposes.
药物基因组学：将基因组学应用于药物遗传学的学科。
Pharmacogenomics --- The application of genomic information or methods to pharmacogenetic problems.
《国际循环》：药物基因组学对高血压预防和治疗策略有何影响？
International Circulation: How does pharmacogenomics affect hypertension prevention and treatment strategies?
胚胎干细胞已成为组织工程、发育生物学、药物开发及基因研究的热点。
Embryonic stem cells have been the focus in tissue engineering, developmental biology, drug development and gene research.
近年来，毒代动力学以及毒理基因组学的飞速发展，解决了传统动物毒性实验中所面临的很多问题，逐步完善了药物安全评价体系。
In recent years, the great development of toxicokinetics and toxicogenomics solved many problems in animal experiments, and consummated the system of assessment of drug safety.
结论：抗精神病药物的神经生物学作用机制可能是一种通过药物作用的“基因治疗”方法。
CONCLUSION: the neurobiological mechanism of antipsychotic drugs may be a method of gene therapy through the effect of drugs.
药物基因组学是研究遗传学与药物反应的相互关系。
Pharmacogenomics is defined as the study of the association between genetics and drug response.
药物基因组学是运用个体或群体的遗传信息来预测某种药物的安全性、毒性和有效性的科学。
Pharmacogenomics is the study of how to predict a drugs reliability, toxicity, and effectiveness based on an individual or a populations genetic information.
本文对基因芯片技术在药学研究(包括中药、药理毒理学和药物基因组学)的应用进行了综述。
Gene chip technology and its applications in pharmaceutical studies, including traditional Chinese medicine, pharmacology and toxicology and pharmacogenomics were reviewed in this paper.
在人类基因组计划完成以及新的生物技术推动下，传统的药物发现模式正在向基因组学为基础的现代药物发现模式转变。
Due to the completion of human genome project and the advent of new technologies, the traditional drug discovery is shifting to genomics-based drug discovery.
药物基因组学帮助我们鉴定个性化药效反应的侧面信息，为同类个体选择最佳的治疗方案。
Pharmacogenomics allows us to identify sources of an individual's profile of drug response and predict the best possible treatment option for this individual.
近几年，国内外学者利用超声联合微泡造影技术所产生的生物学效应，实现了微泡造影剂携载药物和基因对肿瘤的靶向治疗。
Resently years, researchers utilize biological effects generated by microbubble contrast agent combined ultrasound techniques to implement therapy of tumor by microbubble carrying drug and gene.
近年来，随着基因组计划的顺利进行，基因组学对药物设计有着巨大的冲击和影响。
In recent years, with the successful progress of Human Genome Project, genomics shows increasing influence on drug design.
FDA认识到药物基因组学的重要性并且鼓励其在药品研发中使用。
FDA recognizes the importance of pharmacogenomics and encourages its use in drug development.
药物基因组学是一门年轻的学科领域。
药物基因组学在临床药物治疗学和新药开发中具有重要的意义。
Pharmacogenomics plays an important role in clinical pharmaceutics and new drug research and development.
本文介绍了药物基因组学的概念、研究内容和方法及其在临床个体化用药中的应用及意义。
The article introduced the concept, content, methods of pharmacogenomics and its applications in establishing clinical individualized medication.
本文介绍了药物基因组学的概念、研究内容和方法及其在临床个体化用药中的应用及意义。
The article introduced the concept, content, methods of pharmacogenomics and its applications in establishing clinical individualized medication.
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