目的:考察丹参素在大鼠各肠段的吸收动力学特征及不同药物浓度对其的影响。
OBJECTIVE: To investigate the absorption kinetics of danshensu at different intestine segments in rats and the influence of the drug concentration on the absorption kinetics.
无毒而高溶血活性的烷基糖苷可能用于制药和化妆品工业改变药物动力学过程和提高有效物的经皮吸收。
Alkyl glucoside without poison and with high haemolysis active can be used to change the dynamics process of effective matter and raise the skin absorption in the medicine and cosmetic industry.
药物在肠道的吸收呈现一级吸收动力学,吸收机制为被动吸收。
The results indicated that the absorption of carbamazepine complied with the passive transport mechanism and the first order kinetics.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
托吡酯吸收迅速完全,呈线性药物动力学特征,生物利用度高。
TPM can be absorbed quickly and completely, it takes on linely drug dynamical characteristic, has high-level organism usefulness.
目的分别考察芍药苷在大鼠各肠段的吸收动力学特征及不同药物浓度对其的影响。
OBJECTIVE To investigate the absorption kinetics of paeoniflorin at different intestine segments of rats and the influence of the drug solution concentration on the absorption kinetics.
方法:以大鼠在体肠灌流模型从吸收部位、药物浓度考察秦皮甲素的肠吸收动力学情况。
Method: the study was performed by intestinal perfusion model in rats to observe the effect of absorption sites and concentrations on absorption kinetics of aesculin.
方法:以大鼠在体肠灌流模型从吸收部位、药物浓度考察秦皮甲素的肠吸收动力学情况。
Method: the study was performed by intestinal perfusion model in rats to observe the effect of absorption sites and concentrations on absorption kinetics of aesculin.
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