• 目的建立快速推灰色药物动力学模型

    Objective: To establish the grey pharmacokinetics model of the fleetness intravenous infusion.

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  • 结论灰色理论用于建立静脉注射药物动力学模型

    Conclusion: the gray theories can be used for establishing the fleetness intravenous injection pharmacokinetics model.

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  • 结论灰色理论用于建立静脉注射药物动力学模型

    Conclusion: the gray theories can be used for establishing the fleetness intravenous injection pharmacokinetics mode...

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  • 结果灰色动力学模型传统药物动力学模型精度

    Results: The mimesis accuracy of Grey pharmacokinetics model was higher than that of traditional ones.

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  • 两种乳腺癌细胞株模型评价纳米粒介导细胞药物释放动力学机理及纳米粒包囊阿霉素治疗效果

    Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.

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  • 模型利用径向扩散辅料络合作用晶体药物溶出度来表征多个动力学运输和络合过程

    The model characterizes many dynamic transport and complexation processes that include radial diffusion, excipient complexation and crystalline drug dissolution.

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  • 目的研究西沙感染家兔模型中的药物动力学

    OBJECTIVE: To study the pharmacokinetics of moxifloxacin in a rabbit tissue cage model.

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  • 基于改进单纯形算法残数,对药物动力房室模型中的有关参数计算进行了研究。

    By using improved simplex method and residuals method, a calculation based on the parameters of compartment model of pharmacokinetics is presented.

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  • 目的建立一种根据浓度微分特征计算静脉滴注模型药物动力学参数方法

    AIM: To establish a new method for calculating the pharmacokinetic parameters of bi-compartmental drugs based on the plasma level of the drug during the intravenous infusion phase.

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  • 模型参数最佳评价通过最小化模型模拟实验测定药物释放动力学差别获得

    Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.

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  • 肿瘤生物发光交错外流非内流,药代动力学模型成为癌症药物治疗更大障碍

    Pharmacokinetic Modeling of Tumor Bioluminescence Implicates Efflux, and Not Influx, as the Bigger Hurdle in Cancer Drug Therapy.

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  • 本文针对药物动力学特点,利用控制模型给出了稳定性分析方法

    This paper established a control model and proposed the stabilization methods aimed at the characteristic of pharmacokinetics for bolus injection.

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  • 非房室模型评价药物动力学参数

    Pharmacokinetic parameters were assessed with noncompartment model and model-dependent method.

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  • 方法根据反向累加生成GOM(1,1)建模原理,给出快速静脉推药物动力学灰色模型

    Methods: Based on the theory of accumulated generating opposite-direction GOM (1, 1) of the set-up model, the grey pharmacokinetics model of fleetness intravenous infusion was made.

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  • PCNONLIN程序进行药物动力模型数据拟合和参数计算;

    The modelling data were performed with a compartment pharmacokinetic modelling program (PCNONLIN).

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  • 方法大鼠灌流模型吸收部位药物浓度考察秦皮甲素肠吸收动力学情况。

    Method: the study was performed by intestinal perfusion model in rats to observe the effect of absorption sites and concentrations on absorption kinetics of aesculin.

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  • 结论建立了模型药物血管外给药零级释放一级释放药物动力学

    Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.

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  • 结论建立了模型药物血管外给药零级释放一级释放药物动力学

    Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.

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