目的:建立快速推注的灰色药物动力学模型。
Objective: To establish the grey pharmacokinetics model of the fleetness intravenous infusion.
结论:灰色理论可用于建立静脉注射药物动力学模型。
Conclusion: the gray theories can be used for establishing the fleetness intravenous injection pharmacokinetics model.
结论:灰色理论可用于建立静脉注射药物动力学模型。
Conclusion: the gray theories can be used for establishing the fleetness intravenous injection pharmacokinetics mode...
结果:灰色物动力学模型比传统的药物动力学模型拟合精度高。
Results: The mimesis accuracy of Grey pharmacokinetics model was higher than that of traditional ones.
用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.
模型利用径向扩散,辅料络合作用和晶体药物的溶出度来表征多个动力学运输和络合过程。
The model characterizes many dynamic transport and complexation processes that include radial diffusion, excipient complexation and crystalline drug dissolution.
目的:研究莫西沙星在感染家兔模型中的药物动力学。
OBJECTIVE: To study the pharmacokinetics of moxifloxacin in a rabbit tissue cage model.
基于改进的单纯形算法和残数法,对药物动力学房室模型中的有关参数计算进行了研究。
By using improved simplex method and residuals method, a calculation based on the parameters of compartment model of pharmacokinetics is presented.
目的:建立一种根据血药浓度的微分特征计算静脉滴注双室模型药物动力学参数的新方法。
AIM: To establish a new method for calculating the pharmacokinetic parameters of bi-compartmental drugs based on the plasma level of the drug during the intravenous infusion phase.
对模型参数的最佳评价通过最小化模型模拟和实验测定间的药物释放动力学差别来获得。
Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.
肿瘤生物发光交错外流,而非内流,的药代动力学模型成为癌症药物治疗的更大障碍。
Pharmacokinetic Modeling of Tumor Bioluminescence Implicates Efflux, and Not Influx, as the Bigger Hurdle in Cancer Drug Therapy.
本文针对药物动力学的特点,利用控制模型,给出了对其稳定性分析的方法。
This paper established a control model and proposed the stabilization methods aimed at the characteristic of pharmacokinetics for bolus injection.
由非房室和房室模型评价药物动力学参数。
Pharmacokinetic parameters were assessed with noncompartment model and model-dependent method.
方法:根据反向累加生成GOM(1,1)的建模原理,给出快速静脉推注药物动力学的灰色模型。
Methods: Based on the theory of accumulated generating opposite-direction GOM (1, 1) of the set-up model, the grey pharmacokinetics model of fleetness intravenous infusion was made.
PCNONLIN程序进行药物动力学房室模型数据拟合和参数计算;
The modelling data were performed with a compartment pharmacokinetic modelling program (PCNONLIN).
方法:以大鼠在体肠灌流模型从吸收部位、药物浓度考察秦皮甲素的肠吸收动力学情况。
Method: the study was performed by intestinal perfusion model in rats to observe the effect of absorption sites and concentrations on absorption kinetics of aesculin.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
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