药物动力学参数在性别间没有明显差异。
The main pharmacokinetic parameters showed no difference in genders.
由非房室和房室模型评价药物动力学参数。
Pharmacokinetic parameters were assessed with noncompartment model and model-dependent method.
结果:两种片剂药物动力学参数无显著差异。
RESULTS: There was no significant difference between the comparative pharmacokinetic parameters of the two kinds of tablets.
结果表明两者的各药物动力学参数均无明显差异。
The results showed that there was no significant difference in each pharmacokinetic parameters between them.
结论:中药药效决定于药物动力学参数及效应系数。
Conclusion: The effects of Chinese materia medica were all controlled by pharmacokinetic and pharmacodynamic coefficient.
目的:了解大剂量阿糖胞苷化疗后,患者的药物动力学参数及不良反应。
AIM:To observe the pharmacokinetics and adverse drug reaction (ADR) after high dose cytarabine maintenanced chemotherapy in 5 children with acute nonlymphocytic leukemia (ANLL).
目的:研究甲硝唑磷酸酯钾PMP及甲硝唑MTZ在家兔血中的药物动力学参数。
Objective: To study the pharmacokinetics of potassium metronidazole phosphate (PMP) and metronidazole (MTZ) in rabbits.
目的:建立一种根据血药浓度的微分特征计算静脉滴注双室模型药物动力学参数的新方法。
AIM: To establish a new method for calculating the pharmacokinetic parameters of bi-compartmental drugs based on the plasma level of the drug during the intravenous infusion phase.
目的:测定10个男性健康者11个时间点盐酸雷尼替丁泡腾颗粒剂的血药浓度及其药物动力学参数。
OBJECTIVE: To determine serum concentration of ranitidine Hydrochloride Effervescent Granules in 10 normal male at 11 time points.
对模型参数的最佳评价通过最小化模型模拟和实验测定间的药物释放动力学差别来获得。
Optimal estimates of the model parameters were obtained by minimizing the difference between model simulation and experimentally measured drug release kinetics.
获取有关酶动力学参数的细节对于药物开发和临床诊断都是至关重要的。
Acquiring details about the kinetic parameters of enzymes is crucial to both drug development and clinical diagnosis.
基于改进的单纯形算法和残数法,对药物动力学房室模型中的有关参数计算进行了研究。
By using improved simplex method and residuals method, a calculation based on the parameters of compartment model of pharmacokinetics is presented.
用药物累积法测定丁公藤注射液的表观动力学参数。
Apparent pharmacokinetic parameters of Dinggongteng Injection were determined with drug accumulation method.
大多数药物的药代动力学作用可用下列参数加以归纳。
The pharmacokinetic behavior of most drugs can be summarized by the following parameters.
根据血液动力学参数和临床表现分型标准,给予血管活性药物的治疗,对预后有了明确估计,对我们临床上开展心脏外科治疗有一定指导价值。
According to the hemodynamic parameters and the criterion for clinical typing, the vasoactive agents therapy can provide a precise prognosis and the therapy is of certain value in cardiac surgery.
PCNONLIN程序进行药物动力学房室模型数据拟合和参数计算;
The modelling data were performed with a compartment pharmacokinetic modelling program (PCNONLIN).
结论根据药效学参数并结合药代动力学参数,确定合适的给药间隔时间,可以安全、有效、经济地使用抗菌药物。
Conclusion Basing pharmacodynamic and pharmacokinetic parameters, to confirm appropriate interval time using medicine may use antimicrobials safely, rationally and economically.
结论根据药效学参数并结合药代动力学参数,确定合适的给药间隔时间,可以安全、有效、经济地使用抗菌药物。
Conclusion Basing pharmacodynamic and pharmacokinetic parameters, to confirm appropriate interval time using medicine may use antimicrobials safely, rationally and economically.
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