目的研究酮康唑对沙奎那韦的体外代谢和药物代谢动力学的影响。
Aim to investigate the effect of ketoconazole on the metabolism in vitro and pharmacokinetics of saquinavir.
目的研究汉族健康志愿者单剂量静脉滴注盐酸头孢吡肟后的药物代谢动力学。
Objective To study the pharmacokinetics of cefepime after a single intravenous administration in Han healthy Chinese volunteers.
短期和长期安全性评价和预测非常重要,同样重要的还有佐剂本身的药物代谢动力学评价。
Short-term and long-term safety evaluation and prediction are important, as is the evaluation of the pharmacokinetics of the adjuvant alone.
这些试验中的相关的药物代谢动力学和机械学的研究将会考虑到优化药物定量和监测。
Linked pharmacokinetic and mechanistic studies within these trials will allow for optimizing drug dosing and monitoring.
增加身体脂肪含量和减少全身含水量和肌肉数量,可以解释许多药物代谢动力学的变化。
Increased body fat and decreased total body water and muscle mass account for many of the pharmacokinetic changes.
专家咨询和2002年6月GACVS的会议资料表明,乙基汞与甲基汞的药物代谢动力学情况是很不一样的。
Expert advice and data presented to the GACVS in June 2002 indicate that the pharmacokinetics of ethyl and methyl mercury are quite different.
摘要 :本文简要综述了蟾毒它灵的相关研究进展,其研究主要集中在提取分离、抗肿瘤作用机理、药物代谢动力学、毒性及合成等方面。
Abstract : This paper reviews the research progress on bufotalin. It mainly focused on extraction and isolation, anti-tumor mechanism, pharmacokinetics, toxicity, synthetic and so on.
本文综述了右旋美托咪啶的药理学、药物代谢动力学及其在重症监护病室中的临床应用,包括对谵妄的防治、药物本身的安全性和其特殊的可唤醒镇静效应。
This article reviewed the pharmacology, pharmacokinetics and its application in ICU, including its application in prevention and control of delirium, drug safety and its arousal sedation effects.
巴格列酮已经经过一系列临床前期药效药理学、安全药理学、药代动力学或毒性动力学和药物代谢研究的评估。
Balaglitazone has been evaluated in a series of preclinical efficacy pharmacology, safety pharmacology, pharmacokinetic/toxicokinetic, and drug metabolism studies.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
肾脏疾病对高原型排泄分数药物的代谢动力学影响较大。
Renal diseases produce greater effects on the kinetics of drugs with a high fraction excreted unchanged.
探索高通量分析方法,进行氨基寡糖系列化合物的结构与代谢研究、药物动力学多合一筛选。
In exploring of high-throughput pharmacokinetic study, we profiled the isovalertatine family aminooligosaccharides and tried the cassette dosing in pharmacokinetic screening of drug candidates.
探索高通量分析方法,进行氨基寡糖系列化合物的结构与代谢研究、药物动力学多合一筛选。
In exploring of high-throughput pharmacokinetic study, we profiled the isovalertatine family aminooligosaccharides and tried the cassette dosing in pharmacokinetic screening of drug candidates.
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